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1.
Oncogenic Kras G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 + T cells dependent manner.
bioRxiv
; 2023 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36824971
2.
KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells.
Cancer Cell
; 41(9): 1606-1620.e8, 2023 09 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37625401
3.
Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib.
Cancer Res
; 80(21): 4840-4853, 2020 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32928921
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