Asunto(s)
Cromatografía Líquida de Alta Presión/métodos , Hemoglobina Glucada/análisis , Hemoglobinas Anormales/análisis , Análisis Químico de la Sangre/métodos , Diabetes Mellitus Tipo 2/sangre , Diabetes Mellitus Tipo 2/genética , Hemoglobina Glucada/química , Hemoglobina Glucada/genética , Hemoglobinas Anormales/química , Hemoglobinas Anormales/genética , Humanos , Estándares de ReferenciaAsunto(s)
Artefactos , Cromatografía Líquida de Alta Presión/métodos , Diabetes Mellitus Tipo 2/sangre , Hemoglobina Glucada/análisis , Hemoglobinas Anormales/genética , Automatización de Laboratorios , Glucemia/análisis , Diabetes Mellitus Tipo 2/diagnóstico , Diabetes Mellitus Tipo 2/genética , Reacciones Falso Negativas , Hemoglobinas Anormales/análisis , Heterocigoto , Humanos , Masculino , Polimorfismo de Nucleótido Simple , Análisis de Secuencia de ADN , HermanosRESUMEN
We assess the repeatability and relative validity of a Spanish beverage intake questionnaire for assessing water intake from beverages. The present analysis was performed within the framework of the PREDIMED-PLUS trial. The study participants were adults (aged 55-75) with a BMI ≥27 and <40 kg/m², and at least three components of Metabolic Syndrome (MetS). A trained dietitian completed the questionnaire. Participants provided 24-h urine samples, and the volume and urine osmolality were recorded. The repeatability of the baseline measurement at 6 and 1 year was examined by paired Student's t-test comparisons. A total of 160 participants were included in the analysis. The Bland-Altman analysis showed relatively good agreement between total daily fluid intake assessed using the fluid-specific questionnaire, and urine osmolality and 24-h volume with parameter estimates of -0.65 and 0.22, respectively (R² = 0.20; p < 0.001). In the repeatability test, no significant differences were found between neither type of beverage nor total daily fluid intake at 6 months and 1-year assessment, compared to baseline. The proposed fluid-specific assessment questionnaire designed to assess the consumption of water and other beverages in Spanish adult individuals was found to be relatively valid with good repeatability.