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1.
Depletion of plasma thymidine results in growth retardation and mitochondrial myopathy in mice overexpressing human thymidine phosphorylase.
J Biol Chem
; 299(3): 103002, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36773803
2.
Nucleic acid-triggered tumoral immunity propagates pH-selective therapeutic antibodies through tumor-driven epitope spreading.
Cancer Sci
; 114(1): 321-338, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36136061
3.
Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii.
Int J Clin Oncol
; 28(5): 613-624, 2023 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-36961615
4.
Phase I study of TAS-121, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, in patients with non-small-cell lung cancer harboring EGFR mutations.
Invest New Drugs
; 37(6): 1207-1217, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30790152
5.
TAS0612, a Novel RSK, AKT, and S6K Inhibitor, Exhibits Antitumor Effects in Preclinical Tumor Models.
Mol Cancer Ther
; 23(2): 174-186, 2024 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37906695
6.
TAS-121, A Selective Mutant EGFR Inhibitor, Shows Activity Against Tumors Expressing Various EGFR Mutations Including T790M and Uncommon Mutations G719X.
Mol Cancer Ther
; 18(5): 920-928, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30872380
7.
TAS6417/CLN-081 Is a Pan-Mutation-Selective EGFR Tyrosine Kinase Inhibitor with a Broad Spectrum of Preclinical Activity against Clinically Relevant EGFR Mutations.
Mol Cancer Res
; 17(11): 2233-2243, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31467113
8.
TAS6417, A Novel EGFR Inhibitor Targeting Exon 20 Insertion Mutations.
Mol Cancer Ther
; 17(8): 1648-1658, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29748209
9.
Targeted deletion of both thymidine phosphorylase and uridine phosphorylase and consequent disorders in mice.
Mol Cell Biol
; 22(14): 5212-21, 2002 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-12077348
10.
Preparation of anti-orotate phosphoribosyltransferase antibody and its application to immunochemical detection in human tumor cells.
Int J Mol Med
; 16(2): 245-9, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16012756
11.
[Preparation of anti-OPRT antibody for immunochemical detection].
Gan To Kagaku Ryoho
; 32(5): 653-8, 2005 May.
Artículo
en Japonés
| MEDLINE | ID: mdl-15918566
12.
[Gamma-hydroxybutyric acid, a metabolite of UFT, shows anti-angiogenic activities and antitumor effect].
Gan To Kagaku Ryoho
; 29(1): 89-94, 2002 Jan.
Artículo
en Japonés
| MEDLINE | ID: mdl-11816484
13.
The novel VEGF receptor/MET-targeted kinase inhibitor TAS-115 has marked in vivo antitumor properties and a favorable tolerability profile.
Mol Cancer Ther
; 12(12): 2685-96, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24140932
14.
The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells.
Int J Oncol
; 36(5): 1193-200, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20372793
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