RESUMEN
Chronic wounds affect over 6.5 million Americans and are notoriously difficult to treat. Suboptimal oxygenation of the wound bed is one of the most critical and treatable wound management factors, but existing oxygenation systems do not enable concurrent measurement and delivery of oxygen in a convenient wearable platform. Thus, we developed a low-cost alternative for continuous O2 delivery and sensing comprising of an inexpensive, paper-based, biocompatible, flexible platform for locally generating and measuring oxygen in a wound region. The platform takes advantage of recent developments in the fabrication of flexible microsystems including the incorporation of paper as a substrate and the use of a scalable manufacturing technology, inkjet printing. Here, we demonstrate the functionality of the oxygenation patch, capable of increasing oxygen concentration in a gel substrate by 13% (5 ppm) in 1 h. The platform is able to sense oxygen in a range of 5-26 ppm. In vivo studies demonstrate the biocompatibility of the patch and its ability to double or triple the oxygen level in the wound bed to clinically relevant levels.
RESUMEN
This work presents a solution-processed gravure printed antenna on robust transparent nanopaper for potential Radio Frequency Identification (RFID) application. The nanopaper, having excellent dimensional stability in water, was obtained by glutaraldehyde treatment with hydrochloric (HCl) acid as a catalyst. For the first time, a device consisting of RF components for RFIDs was printed on stable nanopaper via a well-developed scalable method: gravure printing. Insertion losses of -37.9 dB and -38.85 dB for the 100 lpi and 120 lpi antennas respectively were demonstrated at the maximum gain of 683.75 MHz. The RF-based responses from the printed antenna demonstrated the feasibility of using printing technology, such as gravure printing, to fabricate flexible RFID antennas for various electronic device applications. This study paves the way for the development of low cost, disposable devices comprised of biodegradable and earth abundant materials to promote greener electronics.