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1.
J Orthop Sci ; 2024 Feb 07.
Artículo en Inglés | MEDLINE | ID: mdl-38331600

RESUMEN

BACKGROUND: In the treatment of patients with calcified midline thoracic disc herniation (CMTDH), the posterior video-assisted transpedicular surgery (VATPS) technique is employed. Both anterior and posterior surgical approaches for treating CMTDH carry a significant risk of surgical complications and potential morbidity. This technical note introduces a surgical procedure that avoids the drawbacks associated with these approaches. METHODS: The VATPS technique presents a comprehensive approach for treating thoracic disc herniation, combining both microscopic and endoscopic stages. The microscopic phase entails a small thoracoscopic incision, muscle release, hemilaminotomy, facet joint resection, and vertebra removal, culminating in creating a corpectomy cavity for endoscope access. Careful separation of adhesions between the dura and ligaments marks this stage. Transitioning to the endoscopic phase, an endoscope is inserted into the cavity, allowing for precise visualization and separation of residual adhesions, removal of calcified disc fragments using specialized instruments, and ensuring complete discectomy. RESULTS: Fourteen patients underwent VATPS for CMTDH. During the procedure, evoked responses were reduced in one patient. However, no postoperative neurological deficits were observed. We also noted significant improvements in the Oswestry Disability Index (ODI) and the Visual Analog Scale (VAS) scores when comparing the preoperative and postoperative assessments. CONCLUSION: VATPS, a minimally invasive technique, offers excellent anterior visibility comparable to that of the anterolateral approach, all while avoiding the adverse effects associated with thoracotomies and the complications resulting from spinal cord encroachment often seen in the posterolateral approach. Moreover, it is a safer alternative to conventional endoscopic posterior thoracic surgery. The cavity formed within the vertebral corpus provides ample working space for the use of an endoscope.

2.
Turk J Med Sci ; 53(5): 1458-1464, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-38813028

RESUMEN

Background/aim: Cervical spondylosis is a progressive disease that causes degenerative changes affecting the spine, intervertebral discs, facets, and ligaments. With anterior and posterior surgical interventions, effective treatments can be applied in cervical spondylotic myelopathy (CSM). The relationship between regional and global spinal alignment and functional and pain outcomes was examined and it was revealed that these parameters play a significant role in obtaining good results. The aim of this study was to compare the perioperative and follow-up results of patients with CSM who underwent laminoplasty or laminectomy with fusion. Materials and method: CSM patients who were operated on between 2015 and 2020 and had at least 2 years of clinical and radiological follow-up were analyzed retrospectively. The patients were divided into 2 groups as the laminoplasty group and the laminectomy with fusion group, according to a simple random method. Demographic, clinical, radiological, and perioperative parameters were examined. Measurements were made by an independent observer using Surgimap and 2 years was considered to be sufficient time for the spine to take its final shape. Result: A total of 112 patients, including 68 males and 44 females, were included. Of these patients, 69 were in the laminectomy with fusion group, and 43 were in the laminoplasty group. Patient ages ranged from 39 to 85 years. The mean follow-up period was 36.28 months. In both groups, at the 3-month follow-up, a statistically significant improvement in the clinical parameters (neck disability index, visual analogue scale, modified Japanese Orthopaedic Association scores) was observed. When the preoperative cervical radiological parameters were evaluated, no statistically significant difference was found between the groups. The C2-C7 lordotic angles and the cervical SVA values were increased in the postoperative period, for both groups (p < 0.001). Although it is noteworthy that the increases were higher in the laminectomy with fusion group, no statistically significant difference was found between the groups. Conclusion: Deformity in a spinal segment may indirectly affect another segment. Being aware of the compensatory mechanisms and radiological parameters will help in determining the effective treatment plan.


Asunto(s)
Vértebras Cervicales , Laminectomía , Laminoplastia , Fusión Vertebral , Espondilosis , Humanos , Femenino , Masculino , Laminoplastia/métodos , Laminectomía/métodos , Espondilosis/cirugía , Espondilosis/diagnóstico por imagen , Persona de Mediana Edad , Anciano , Fusión Vertebral/métodos , Vértebras Cervicales/cirugía , Vértebras Cervicales/diagnóstico por imagen , Estudios Retrospectivos , Adulto , Anciano de 80 o más Años , Resultado del Tratamiento , Equilibrio Postural/fisiología
3.
Langmuir ; 38(33): 10098-10113, 2022 Aug 23.
Artículo en Inglés | MEDLINE | ID: mdl-35946525

RESUMEN

Adsorption is a widely used method for pollution removal and for the recovery of valuable species. In recent years, the use of metal-organic compounds among the adsorbents used in adsorption studies has increased. In this study, the performance of the water-insoluble Fe complex as a metal organic framework (MOF-Fe-Ta) of water-soluble tannic acid, which is not used as an adsorbent in uranium recovery and removal, was investigated. For the characterization of the new synthesized material, Fourier transform infrared, scanning electron microscopy, and X-ray diffraction analyses were performed. The changes in the adsorption process based on various parameters were investigated and discussed. The point of zero charges value of the adsorbent was found as 5.52. It was noticed that the adsorption increases as the pH increases. Analyzing the effect of concentration on adsorption, we determined which model explained the adsorption better. The monolayer capacity of the adsorbent determined in light of the Langmuir model was reported as 0.347 mol kg-1. The Freundlich constant, namely the ß value obtained in the Freundlich model, which is a measure of surface heterogeneity, was found to be 0.434, and the EDR value, which was found from the Dubinin-Raduskevich model and accepted as a measure of adsorption energy, was 10.3 kJ mol-1. The adsorption was kinetically explained by the pseudo-second-order model and the adsorption rate constant was reported as 0.15 mol-1 kg min-1. The effect of temperature on adsorption was studied; it was emphasized that adsorption was energy consuming, that is, endothermic and ΔH was found as 7.56 kJ mol-1. The entropy of adsorption was positive as 69.3 J mol-1 K-1. As expected, the Gibbs energy of adsorption was negative (-13.1 kJ mol-1 at 25 °C), so adsorption was considered as a spontaneous process. Additionally, the power and mechanism of the interaction between studied adsorbent and adsorbate are explained through density functional theory computations. Computationally obtained data supported the experimental studies.

4.
Cent Eur J Public Health ; 29(3): 183-186, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-34623116

RESUMEN

OBJECTIVES: The modern rise of vaccine rejection in society can alter the current progress that has been made towards the control and prevention of certain diseases, possibly even resulting in epidemics involving these preventable diseases. The aim of this study is to analyse the knowledge, attitude and behaviours of parents in Malatya city who rejected childhood vaccines. METHODS: This descriptive, cross-sectional study was conducted between September-November 2019. The study includes parents who rejected vaccines and are registered in the family medicine clinics of Malatya city - total of 453 participants. The objective was to include all parents and avoid a sampling procedure. However, only 151 (33%) parents agreed to participate. These parents who rejected vaccines were individually contacted by phone. Descriptive data was represented by number (n) and percentage (%). The chi-square test was utilized in the statistical analysis of data and p < 0.05 was considered significant in all evaluations. RESULTS: Mothers in the study group had a mean age of 26.07 ± 3.64, while the fathers were on average 30.03 ± 4.59 years of age; 98% of parents were aware of the health risks that vaccine rejection presented; 93% of parents were not satisfied with the explanation, insight, and advice that the healthcare personnel provided regarding vaccines. All parents of the study group stated the following: vaccines should not be administered because other children in their close environment acquired a disease as a result of vaccination, vaccines can harm the immune system of children - not yet fully developed, vaccines are unsafe and endanger the health of children. CONCLUSIONS: It can be said that parents who have obtained a lot of false information possess altered decisions and views on vaccinations, to the point where they accept the risks presented by preventable diseases. In addition, individuals lose trust following negative experiences with vaccination.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Vacunas , Adulto , Niño , Estudios Transversales , Femenino , Humanos , Padres , Turquía
5.
Pak J Med Sci ; 37(4): 1201-1205, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34290808

RESUMEN

OBJECTIVE: Problematic cell phone use is common among young age groups which include university students, and may be accompanied by social anxiety and eating disorders. We aimed to examine the relationship between problematic cell phone use, social anxiety and eating disorders among university students. METHODS: The universe of this cross-sectional study consists of 28,669 students receiving education at a Inonu University between October 2017 - November 2017. With a confidence interval of 95% and power of 80%, the sample size was calculated to be 308. The survey forms used in the study included students' sociodemographic characteristics, data regarding cell phone usage, Problematic Mobile Phone Use Scale, Liebowitz Social Anxiety Scale and Eating Attitudes Test. The statistical analyses were conducted using Student t, One Way ANOVA, Spearman Correlation Test and Binomial Logistic Regression Analysis. RESULTS: The students in the study group demonstrated a 46.1% rate of problematic cell phone use. The students' Problematic Mobile Phone Use Scale total scores showed a significant correlation with smoking, and daily duration and purpose of cell phone use (p<0.05). CONCLUSION: University students demonstrate high rates of problematic cell phone use; in addition, individuals who use cell phones for increased hours or for certain purposes display higher total scores on the Problematic Mobile Phone Use Scale. Students should be educated on limiting problematic cell phone use.

6.
J Cancer Educ ; 35(4): 718-723, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-30937881

RESUMEN

Health workers play an important role in the early detection of cancer and encouraging people to participate in screening tests. This study aimed to analyze the knowledge, attitude, and practice of health workers regarding cancer screening and to determine variables that affect their behavior in undergoing in screening tests. This descriptive study was conducted among 475 health workers (84 assistant doctors, 306 nurses, 65 midwives, and 20 other professionals) in a university hospital. The questionnaire included sociodemographic questions (age, profession, years of experience, and family history of cancer) and questions about the workers' knowledge, attitude, and practice regarding cancer screening. It was found that half of the participants had inadequate knowledge of cancer screening methods (50.3% for Pap smear, 57.5% for mammography, 68.4% for colonoscopy, and 54.3% for fecal occult blood). Although the attitudes of the health workers were mostly positive (above 90% for all screening tests), their practice of screening methods was low (for example 25.7% of them practiced mammography and 4.2% pap smear). Older health workers, those with a family history of cancer, and those with more than 11 years of experience tended to participate in cancer screening tests more often than health workers who were younger, had no family history of cancer history, and whose experience was less than 10 years (p < 0.05). A health worker's profession was not an important factor in their practice of undergoing screening tests (p > 0.05).


Asunto(s)
Detección Precoz del Cáncer/estadística & datos numéricos , Conocimientos, Actitudes y Práctica en Salud , Personal de Salud/psicología , Hospitales Universitarios/normas , Neoplasias/prevención & control , Adulto , Detección Precoz del Cáncer/psicología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Neoplasias/diagnóstico , Neoplasias/epidemiología , Encuestas y Cuestionarios , Turquía/epidemiología , Adulto Joven
7.
Pediatr Transplant ; 23(4): e13406, 2019 06.
Artículo en Inglés | MEDLINE | ID: mdl-30932299

RESUMEN

LKT is the only effective treatment for PH1 because it replaces both the source (liver) and the target (kidney) of the disease. Most studies report on LKT in patients with PH1 from deceased donors. This study reports on five patients who underwent LKT from a single living  donor between April 2017 and March 2018. Combined LKT was performed for 1 patient and sequential LKT for the remainder. The median age of the patients at the time of diagnosis and transplantation was 5.5 (0.3-18) and 10 (6-21) years, respectively. All patients received left lateral liver segment transplantation, except one patient who received right liver lobe transplantation. No liver graft loss was observed, and liver function tests were stable at the final evaluation of all patients. Renal function tests of the patients were also stable at the final assessment, except for the young adult patient. None of the patients suffered from acute rejection. One patient died at the second month following liver transplantation due to severe pneumonia and sepsis. This study concludes that combined or sequential LKT from a single living donor can be safely performed and provides encouraging results for even the youngest and smallest patients with PH1.


Asunto(s)
Hiperoxaluria Primaria/cirugía , Trasplante de Riñón/métodos , Trasplante de Hígado/métodos , Obtención de Tejidos y Órganos/métodos , Adolescente , Niño , Preescolar , Femenino , Humanos , Lactante , Donadores Vivos , Masculino , Neumonía/complicaciones , Estudios Retrospectivos , Sepsis/complicaciones , Resultado del Tratamiento , Adulto Joven
8.
Med Princ Pract ; 26(2): 125-131, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-27829248

RESUMEN

OBJECTIVE: The present study was undertaken to investigate the prognostic value of the frontal planar QRS-T angle in patients without angiographically apparent coronary atherosclerosis. SUBJECTS AND METHODS: Three hundred and seven patients with normal coronary arteries on coronary angiography were included. The absolute difference between the frontal QRS- and T-wave axes was defined as the frontal planar QRS-T angle, and patients were divided into 3 subgroups based on the frontal planar QRS-T angle (<45, 45-90, and >90°). Demographic, clinical, laboratory, and angiographic data were compared between groups. Based on the regression analysis results, patients were recategorized into 4 groups according to their luminal calibers of left main coronary artery (LMCA) and history of hypertension (HT) (nonhypertensive LMCA ≤4.13 mm, nonhypertensive LMCA >4.13 mm, hypertensive LMCA ≤4.13 mm, and hypertensive LMCA >4.13 mm). RESULTS: The median value of the frontal planar QRS-T angle of all participants was 38°. Subjects with the widest frontal planar QRS-T angle were older (p = 0.027), were hypertensive (p = 0.001), and had higher corrected QT values (p = 0.001). Patients with the widest frontal planar QRS-T angle had larger LMCA and left anterior descending coronary artery diameters compared to subjects with a normal and borderline frontal QRS-T angle (p = 0.004 and p = 0.028, respectively). Corrected QT, HT, and LMCA diameter were found as independent predictors of the frontal planar QRS-T angle. Subjects with HT and a larger luminal caliber of LMCA had the widest frontal planar QRS-T angle. CONCLUSION: Patients with a history of HT and a larger luminal caliber of LMCA had the widest frontal planar QRS-T angle. Since HT-induced electrophysiological changes are still not well established and we observed that changes in the luminal caliber of coronary arteries are associated with an abnormal frontal QRS-T angle, the frontal QRS-T angle could serve as a marker of ventricular repolarization heterogeneity in hypertensive patients in addition to keeping track of arrhythmic events, even before overt disease.


Asunto(s)
Aterosclerosis/diagnóstico , Aterosclerosis/epidemiología , Vasos Coronarios/diagnóstico por imagen , Electrocardiografía , Hipertensión/epidemiología , Adulto , Factores de Edad , Anciano , Aterosclerosis/diagnóstico por imagen , Aterosclerosis/fisiopatología , Angiografía Coronaria , Femenino , Humanos , Hipertensión/fisiopatología , Masculino , Persona de Mediana Edad , Factores de Riesgo , Factores Socioeconómicos
9.
Artículo en Inglés | MEDLINE | ID: mdl-27405125

RESUMEN

The purpose of this study was to determine the knowledge levels of Inonu University medical faculty students regarding Ebola. This descriptive, cross sectional study was conducted between November and December, 2014 at Inonu University Medical Faculty. After the researchers performed the literature review, a questionnaire comprising 39 questions was prepared, and the students were asked to fill them out. Nine hundred and eighty-four of 1,298 students (75.8%) participated in the study. Seventy-three point seven percent knew that the Ebola virus disease had high fatality rate, 51.9% of them knew that the primary method of infection was contact with the secretions of dead animals and humans, and 55.2% knew that it was transmitted via the blood of infected animals. The rate of knowing that there was no specific vaccination was 62.1%, while the knowledge that there was no specific treatment was 45.3%; 80.4% knew that all the people entering the patient's room had to wear gloves and liquid-resistant aprons, and 77.3% knew that the number of the staff caring for the patient must be reduced to the minimum level. Three knowledge points were calculated in the study: 'Knowledge Points on Ebola Virus Disease Factor Properties and the Methods of Infection,' 'Ebola Virus Disease Symptom Knowledge Points,' and 'Ebola Virus Disease Protection Knowledge Points.' In terms of these knowledge points, the knowledge levels of the students between the classes were significantly different.


Asunto(s)
Conocimientos, Actitudes y Práctica en Salud , Fiebre Hemorrágica Ebola , Estudiantes de Medicina/estadística & datos numéricos , Estudios Transversales , Femenino , Humanos , Masculino , Turquía/epidemiología
10.
J Trop Pediatr ; 61(3): 188-96, 2015 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25828832

RESUMEN

AIM: The present study aims to determine the knowledge, attitudes and views of mothers regarding infant feeding, breast milk, wet-nursing, milk kinship and human milk banks. METHODS: This descriptive cross-sectional study was composed of 1042 mothers who delivered at two different hospitals in Turkey. RESULTS: Almost half of the participating mothers, 49.9%, agreed with the establishment of alternative HMBs in Turkey. Only 7.7% of the mothers in this study expressed views in favour of the establishment of Western-style HMBs. Approximately half of the mothers (42.4%) indicated that they were against the establishment of any kind of HMBs in Turkey. Only 9.2% of the mothers in this study stated that they would volunteer to donate their breast milk to the Western-style HMBs, and only 6.9% of the mothers approved obtaining milk from this type of HMB. Finally, 44.2% of the mothers stated that they would donate their breast milk to the alternative HMBs, and 31.9% of the mothers approved obtaining milk from this type of HMB. CONCLUSION: This is the first study conducted among mothers in a Muslim community about issues such as infant feeding, breast milk, wet-nursing, milk kinship and HMBs. The majority of the mothers in this study are against the establishment of Western-style HMBs, whereas they have a more positive response to an alternative HMB when their religious concerns are relieved.


Asunto(s)
Lactancia Materna/etnología , Conocimientos, Actitudes y Práctica en Salud , Islamismo/psicología , Bancos de Leche Humana , Leche Humana , Madres/psicología , Adulto , Estudios Transversales , Femenino , Humanos , Bancos de Leche Humana/ética , Bancos de Leche Humana/organización & administración , Medio Social , Percepción Social , Factores Socioeconómicos , Encuestas y Cuestionarios , Turquía
11.
J Pediatr Gastroenterol Nutr ; 58(5): 608-12, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-24792628

RESUMEN

OBJECTIVES: There are limited data regarding the pattern of Helicobacter pylori (Hp) antibiotic resistance and virulence factors in children. Evaluation of prevalence of drug resistance and virulence-factor genotype in children with Hp gastritis and to investigate whether there is any relation between drug resistance and genotype were our aims in this study. METHODS: Ninety-eight children with polymerase chain reaction-positive Hp gastritis were included. Antimicrobial susceptibility was tested by disc diffusion method and polymerase chain reaction assays were used for the determination of virulence factors. RESULTS: The resistance rates to clarithromycin, metronidazole, and amoxicillin were 23.5%, 11.7%, and 3.9%, respectively. All strains carried vacA genotype, and 51%, 70.4%, 49%, 34.7%, and 25.5% were cagA-, cagE-, babA2-, iceA1-, and iceA2-positive, respectively. Of those 98 specimens, 81.6%, 19.4%, 38.8%, and 63.3% carried vacAs1, vacAs2, vacAm1, and vacAm2, respectively. Dominant vacA type was s1am2 (32.7%), followed by s1am1 (14.3%) and s2m2 (12.2%). Significant rates of clarithromycin resistance were observed in cagE-, iceA1-, babA2-, and vacAs1c-positive groups. In those with metronidazole resistance, vacAs1 and vacAs1c were more common (P < 0.05). CONCLUSIONS: The cagE-positive and vacA s1a/m2 genotypes, which are correlated with increased antibiotic resistance, were predominant in our population. In countries where Hp infection is prevalent, studies focusing on virulence factors and antibiotic susceptibility may provide anticipation of the prognosis and may be helpful to reduce morbidity and mortality.


Asunto(s)
Farmacorresistencia Bacteriana , Gastritis/microbiología , Infecciones por Helicobacter/tratamiento farmacológico , Helicobacter pylori , Factores de Virulencia/genética , Adolescente , Niño , Preescolar , ADN Bacteriano/análisis , Gastritis/tratamiento farmacológico , Genotipo , Humanos , Pruebas de Sensibilidad Microbiana , Reacción en Cadena de la Polimerasa , Factores de Virulencia/análisis
12.
Childs Nerv Syst ; 30(7): 1307-11, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-24442139

RESUMEN

PURPOSE: Choroid plexus papillomas (CPP) are rare benign neoplasms of the central nervous system that occur most often in children during the first decade of life. They occur most often in the lateral ventricle. It is extremely rare for a CPP to occur in the pineal region. We describe the case of a child with a CPP located in the pineal region, who was initially diagnosed with obstructive hydrocephalus by cranial computed tomography (CT). METHODS: A 9-year-old female patient presented with complaints of visual disturbance, nausea, and vomiting. Magnetic resonance imaging (MRI) showed a poor contrast-enhanced pineal-localized lesion. Anatomical variations within the patient caused her surgery to proceed using a supratentorial-occipital interhemispheric approach. RESULTS: The tumor was totally removed, and a histological examination revealed the tumor to be a typical CPP. The patient received follow-up neurological and ophthalmologic examinations at 3, 6, 9, 12, 24, and 36 months postoperatively, which demonstrated her progressive improvement. CONCLUSIONS: CPPs may have a wide range of locations and resulting symptoms. However, the pineal region is a rarely encountered location, particularly for pediatric patients. It is of great value to correctly differentiate neoplasms such as germ cell tumors, pineocytomas, meningiomas, and astrocytomas, so that patients receive the correct diagnosis and treatment approach.


Asunto(s)
Papiloma del Plexo Coroideo/patología , Pinealoma/patología , Derivaciones del Líquido Cefalorraquídeo , Niño , Comorbilidad , Femenino , Humanos , Hidrocefalia/epidemiología , Procedimientos Neuroquirúrgicos , Papiloma del Plexo Coroideo/epidemiología , Papiloma del Plexo Coroideo/cirugía , Pinealoma/epidemiología , Pinealoma/cirugía
13.
J Biomech Eng ; 136(5): 051007, 2014 May.
Artículo en Inglés | MEDLINE | ID: mdl-24599026

RESUMEN

Currently, rigid fixation systems are the gold standard for degenerative disk disease treatment. Dynamic fixation systems have been proposed as alternatives for the treatment of a variety of spinal disorders. These systems address the main drawbacks of traditional rigid fixation systems, such as adjacent segment degeneration and instrumentation failure. Pedicle-screw-based dynamic stabilization (PDS) is one type of these alternative systems. The aim of this study was to simulate the biomechanical effect of a novel posterior dynamic stabilization system, which is comprised of dynamic (hinged) screws interconnected with a coiled, spring-based dynamic rod (DSDR), and compare it to semirigid (DSRR and RSRR) and rigid stabilization (RSRR) systems. A validated finite element (FE) model of L1-S1 was used to quantify the biomechanical parameters of the spine, such as range of motion, intradiskal pressure, stresses and facet loads after single-level instrumentation with different posterior stabilization systems. The results obtained from in vitro experimental intact and instrumented spines were used to validate the FE model, and the validated model was then used to compare the biomechanical effects of different fixation and stabilization constructs with intact under a hybrid loading protocol. The segmental motion at L4-L5 increased by 9.5% and 16.3% in flexion and left rotation, respectively, in DSDR with respect to the intact spine, whereas it was reduced by 6.4% and 10.9% in extension and left-bending loads, respectively. After instrumentation-induced intradiskal pressure at adjacent segments, L3-L4 and L5-S1 became less than the intact in dynamic rod constructs (DSDR and RSDR) except in the RSDR model in extension where the motion was higher than intact by 9.7% at L3-L4 and 11.3% at L5-S1. The facet loads were insignificant, not exceeding 12N in any of the instrumented cases in flexion. In extension, the facet load in DSDR case was similar to that in intact spine. The dynamic rod constructions (DSDR and RSDR) led to a lesser peak stress at screws compared with rigid rod constructions (DSRR and RSRR) in all loading cases. A dynamic construct consisting of a dynamic rod and a dynamic screw did protect the adjacent level from excessive motion.


Asunto(s)
Tornillos Óseos , Análisis de Elementos Finitos , Fenómenos Mecánicos , Fenómenos Biomecánicos , Degeneración del Disco Intervertebral/cirugía , Vértebras Lumbares/lesiones , Vértebras Lumbares/fisiología , Dinámicas no Lineales , Rango del Movimiento Articular
14.
Pak J Med Sci ; 30(6): 1259-64, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-25674119

RESUMEN

OBJECTIVES: Hemodynamic status, cardiac enzymes, and imaging-based risk stratification are frequently used to evaluate a pulmonary embolism (PE). This study investigated the prognostic role of a simplified Pulmonary Embolism Severity Index (sPESI) score and the European Society of Cardiology (ESC) model. Methods : The study included 50 patients from the emergency and pulmonology department of one medical center between October 2005 and June 2006. The ability of the sPESI and ESC model to predict short-term (in-hospital) and long-term (6-month and 6-year) overall mortality was assessed, in addition to the accurancy of the sPESI and ESC model in predicting short-term adverse events, such as cardiopulmonary resuscitation, or major bleeding. Results : Of the 50 patients, the in-hospital and 6-year mortality rates were 14% and 46%, respectively. Fifteen (30%) of these experienced adverse events during hospitalization. Importantly, patients classified as low-risk according to the sPESI had no short-term adverse events as opposed to 4.8 % in the ESC low-risk group. They also had no in-hospital, 6-month, or 6-year mortality compared to 4.8%, %14.3, and %23.8, respectively, in the ESC low-risk group. CONCLUSIONS: The sPESI predicted short-term and long-term survival. The exclusion of short-term adverse events does not appear to require imaging and laboratory testing.

15.
Turk Neurosurg ; 34(2): 256-262, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38497178

RESUMEN

AIM: To evaluate the outcomes of dynamic stabilization in the multilevel degenerative spondylotic spine, and to compare the two dynamic systems (Dynesys® and Orthrus®) to reveal the increasing role of dynamic systems in the management of the degenerative spine. MATERIAL AND METHODS: A total of 74 patients who received dynamic stabilization for degenerative pathologies were retrospectively analyzed. Demographic details: preoperative data including neurological status, pain scores, and radiology; and intraoperative data including blood loss, duration of surgery, complications, and postoperative data including the neurologic status, duration of hospital stay, and pain scores were examined. RESULTS: Patients in both groups showed statistically significant improvements in their Visual Analog Scale and Oswestry Disability Index scores. Significant corrections of thoracic kyphosis (T2-T12), the sagittal vertical axis, and T10-L2 thoracolumbar kyphosis were obtained in our cohort (p < 0.05). A total of 4 patients received revision surgery due to screw loosening. Patients were discharged after 3-4 days and mobilized on the first postoperative day. CONCLUSION: We did not experience any serious issues in terms of stabilization in the cases in which we employed both systems. Our patients' clinical results were satisfactory in both systems. Existing systems can be used safely even in long-segment stabilization surgeries.


Asunto(s)
Cifosis , Fusión Vertebral , Humanos , Resultado del Tratamiento , Vértebras Lumbares/diagnóstico por imagen , Vértebras Lumbares/cirugía , Estudios Retrospectivos , Fusión Vertebral/métodos , Cifosis/diagnóstico por imagen , Cifosis/cirugía , Dolor , Vértebras Torácicas/diagnóstico por imagen , Vértebras Torácicas/cirugía
16.
Biomed Mater Eng ; 35(1): 39-52, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-37545207

RESUMEN

BACKGROUND: We compared the raw Ti-Al-V super alloy transpedicular implant screws with boronized and surface-hardened transpedicular implant screws. OBJECTIVE: To improve patients' postoperative prognosis with the production of harder and less fragile screws. METHODS: Surface hardening was achieved by applying green-body encapsulation of the specimen with elemental boron paste which is sintered at elevated temperatures to ensure the boron-metal diffusion. Boron transported into the Ti-Al-V super alloy matrix gradually while suppressing aluminum and a homogeneously boronized surface with a thickness of ∼15 microns was obtained. The uniform external shell was enriched with TiB2, which is one of the hardest ceramics. The Ti-Al-V core material, where boron penetration diminishes, shows cohesive transition and ensures intact core-surface structure. RESULTS: Scanning electron microscope images confirmed a complete homogeneous, uniform and non-laminating surface formation. Energy-dispersive X-ray monitored the elemental structural mapping and proved the replacement of the aluminum sites on the surface with boron ending up the TiB2. The procedure was 8.6 fold improved the hardness and the mechanical resistance of the tools. CONCLUSIONS: Surface-hardened, boronized pedicular screws can positively affect the prognosis. In vivo studies are needed to prove the safety of use.


Asunto(s)
Aluminio , Titanio , Humanos , Titanio/química , Boro , Aleaciones/química , Prótesis e Implantes , Propiedades de Superficie
17.
Neurochirurgie ; 70(4): 101555, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38520969

RESUMEN

Syringomyelia associated with extensive spinal adhesive arachnoiditis (SAA) can be defined as a rare but progressive disease with potentially devastating clinical consequences. Diagnosis can be challenging due to the absence of specific clinical findings, confusion with other pathologies, and late imaging modalities. The treatment strategy for syringomyelia associated with extensive SAA should include direct drainage of the syringomyelia, and dissection of the adhesive arachnoid with expansive duraplasty. Hence, several approaches have been reported for arachnoid dissection and decompression of the subarachnoid space. The high risk of recurrence after the operation is one of the most challenging situations. First two cases were operated previously, and the cyst walls were removed and anastomosed to the intact subarachnoid space at the upper and lower ends by each other. However, in both cases, the cyst recurred after a short time and they were anastomosed again in our clinic. A subarachnoid-subarachnoid shunt was placed with a multi-hole silicone tube extending to the proximal and distal intact subarachnoid spaces and passing through the cyst removal area. In our third case, the shunt system we described was applied directly, and satisfactory results were obtained in the clinical follow-up of the patient. It has been demonstrated that subarachnoido-subarachnoid shunt is a very satisfactory treatment option for this type of pathology, which is difficult to follow and treat.


Asunto(s)
Quistes Aracnoideos , Aracnoiditis , Espacio Subaracnoideo , Humanos , Quistes Aracnoideos/cirugía , Quistes Aracnoideos/complicaciones , Espacio Subaracnoideo/cirugía , Aracnoiditis/cirugía , Aracnoiditis/etiología , Masculino , Femenino , Siringomielia/cirugía , Siringomielia/etiología , Persona de Mediana Edad , Adulto , Derivaciones del Líquido Cefalorraquídeo/métodos , Recurrencia , Resultado del Tratamiento , Descompresión Quirúrgica/métodos , Imagen por Resonancia Magnética , Procedimientos Neuroquirúrgicos/métodos
18.
World Neurosurg ; 188: e567-e572, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38825312

RESUMEN

OBJECTIVE: To investigate the anatomical parameters of the ideal screw trajectory for percutaneous intralaminar screw fixation of a pars defect in lumbar spondylolysis using computed tomography scans. METHODS: Using advanced radiological software, the ideal intralaminar screw trajectory was determined. The anatomical parameters of this trajectory were analyzed using a total of 80 single-level lumbar tomography scans in patients with spondylolysis at the lumbar 4 vertebrae and lumbar 5 vertebrae levels. The ideal intralaminar screw trajectory started from the inferolateral edge of the lamina and was between the intralaminar region, pars defect, and defective pars neck and pedicle. Along this trajectory, the skin-lamina distance, intralaminar screw length, isthmic lamina length and width, defective pars neck width, lateral entry distance of the screw to the center of the spinous process, and sagittal and coronal screw application angles were analyzed. RESULTS: When comparing the lumbar 4 vertebrae and lumbar 5 vertebrae parameters, the mean skin-to-lamina distances were 11-9 cm (P = 0.000), intralaminar screw lengths 3.5-3.6 cm (P = 0.067), isthmic lamina lengths 2-2 cm (P = 0.698), mid-lamina widths 1-1 cm (P = 0.941), defective pars neck widths 1-1 cm (P = 0.674), screw lateral entry distances according to the spinous process 1-1.5 cm (P = 0.000), sagittal screw angles 45°-45° (P = 0.870), and coronal screw angles 10°-20° (P = 0.000), respectively. There were no differences based on age and gender (P < 0.05). CONCLUSIONS: Percutaneous intralaminar rigid screw fixation of a pars defect in spondylolysis provides minimally invasive, low-profile instrumentation. In spondylolysis, a screw length of 3-4 cm and a screw diameter of 4-5 mm may be sufficient for pars fixation with intralaminar screws.


Asunto(s)
Tornillos Óseos , Vértebras Lumbares , Espondilólisis , Humanos , Espondilólisis/cirugía , Espondilólisis/diagnóstico por imagen , Femenino , Masculino , Vértebras Lumbares/cirugía , Vértebras Lumbares/diagnóstico por imagen , Persona de Mediana Edad , Adulto , Anciano , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Tomografía Computarizada por Rayos X , Adulto Joven , Fusión Vertebral/métodos , Fusión Vertebral/instrumentación , Estudios Retrospectivos
19.
Diagnostics (Basel) ; 14(14)2024 Jul 12.
Artículo en Inglés | MEDLINE | ID: mdl-39061642

RESUMEN

BACKGROUND: Dynamic lumbar stabilization aims to preserve spinal movement, offering stability and controlled motion. However, screw loosening, especially in patients with osteopenia and osteoporosis, remains challenging. METHOD: Between 2018 and 2022, a retrospective analysis was conducted on a total of 119 patients diagnosed with osteopenia and osteoporosis who underwent spinal dynamic instrumentation surgery. These patients were categorized into two groups: single-stage surgery (n = 67) and two-stage surgery (n = 52). Over the 48-month follow-up period, the occurrence and percentage of screw loosening were examined at each surgical level per patient, as well as by screw location (pedicular, corpus, tip). Clinical outcomes were evaluated using Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) scores. RESULTS: Total screw loosening rates were significantly lower in the two-stage group (2.83%) compared to the single-stage group (14.63%, p < 0.001). Patient-based loosening occurred in 5 patients (9.6%) in the two-stage group and 16 patients (23.9%) in the single-stage group. Loosening rates were lower in the two-stage group at L2 (7.78%, p = 0.040), L3 (5.56%, p < 0.001), L4 (8.89%, p = 0.002), and L5 (10.00%, p = 0.006), but higher at S1 (21.11%, p = 0.964), T12 (15.56%, p = 0.031), and iliac levels (15.56%, p = 0.001). Pedicular section exhibited the highest loosening (37 cases). VAS and ODI scores improved significantly in both groups, with better outcomes in the two-stage group at the 48. months (p < 0.001). CONCLUSIONS: The two-stage surgical approach significantly reduces screw loosening in patients with osteopenia and osteoporosis undergoing dynamic stabilization surgery, offering enhanced stability and better clinical outcomes.

20.
Diagnostics (Basel) ; 14(16)2024 Aug 07.
Artículo en Inglés | MEDLINE | ID: mdl-39202200

RESUMEN

OBJECTIVE: In spine surgery, ensuring the safety of vital structures is crucial, and various instruments contribute to the surgeon's confidence. This study aims to present outcomes from spinal cases operated on using the freehand technique and neuronavigation with an O-arm in our clinic. Additionally, we investigate the impact of surgical experience on outcomes by comparing early and late cases operated on with neuronavigation. METHOD: We conducted a retrospective analysis of spinal patients operated on with the freehand technique and neuronavigation in our clinic between 2019 and 2020, with a minimum follow-up of 2 years. Cases operated on with neuronavigation using the O-arm were categorized into early and late groups. RESULTS: This study included 193 patients, with 110 undergoing the freehand technique and 83 operated on utilizing O-arm navigation. The first 40 cases with neuronavigation formed the early group, and the subsequent 43 cases comprised the late group. The mean clinical follow-up was 29.7 months. In the O-arm/navigation group, 796 (99%) of 805 pedicle screws were in an acceptable position, while the freehand group had 999 (89.5%) of 1117 pedicle screws without damage. This rate was 98% in the early neuronavigation group and 99.5% in the late neuronavigation group. CONCLUSIONS: The use of O-arm/navigation facilitates overcoming anatomical difficulties, leading to significant reductions in screw malposition and complication rates. Furthermore, increased experience correlates with decreased surgical failure rates.

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