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1.

Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.

Louphrasitthiphol, Pakavarin; Siddaway, Robert; Loffreda, Alessia; Pogenberg, Vivian; Friedrichsen, Hans; Schepsky, Alexander; Zeng, Zhiqiang; Lu, Min; Strub, Thomas; Freter, Rasmus; Lisle, Richard; Suer, Eda; Thomas, Benjamin; Schuster-Böckler, Benjamin; Filippakopoulos, Panagis; Middleton, Mark; Lu, Xin; Patton, E Elizabeth; Davidson, Irwin; Lambert, Jean-Philippe; Wilmanns, Matthias; Steingrímsson, Eiríkur; Mazza, Davide; Goding, Colin R.

Mol Cell ; 79(3): 472-487.e10, 2020 08 06.

Artículo en Inglés | MEDLINE | ID: mdl-32531202

2.

Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells.

Brunsdon, Hannah; Brombin, Alessandro; Peterson, Samuel; Postlethwait, John H; Patton, E Elizabeth.

Development ; 149(10)2022 05 15.

Artículo en Inglés | MEDLINE | ID: mdl-35485397

3.

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish.

Camargo-Sosa, Karen; Colanesi, Sarah; Müller, Jeanette; Schulte-Merker, Stefan; Stemple, Derek; Patton, E Elizabeth; Kelsh, Robert N.

PLoS Genet ; 15(2): e1007941, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30811380

4.

Spontaneously occurring melanoma in animals and their relevance to human melanoma.

van der Weyden, Louise; Brenn, Thomas; Patton, E Elizabeth; Wood, Geoffrey A; Adams, David J.

J Pathol ; 252(1): 4-21, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32652526

5.

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.

Ngeow, Kao Chin; Friedrichsen, Hans J; Li, Linxin; Zeng, Zhiqiang; Andrews, Sarah; Volpon, Laurent; Brunsdon, Hannah; Berridge, Georgina; Picaud, Sarah; Fischer, Roman; Lisle, Richard; Knapp, Stefan; Filippakopoulos, Panagis; Knowles, Helen; Steingrímsson, Eiríkur; Borden, Katherine L B; Patton, E Elizabeth; Goding, Colin R.

Proc Natl Acad Sci U S A ; 115(37): E8668-E8677, 2018 09 11.

Artículo en Inglés | MEDLINE | ID: mdl-30150413

6.

Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.

Scahill, Catherine M; Digby, Zsofia; Sealy, Ian M; Wojciechowska, Sonia; White, Richard J; Collins, John E; Stemple, Derek L; Bartke, Till; Mathers, Marie E; Patton, E Elizabeth; Busch-Nentwich, Elisabeth M.

PLoS Genet ; 13(8): e1006959, 2017 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-28806732

7.

The melanocyte lineage in development and disease.

Mort, Richard L; Jackson, Ian J; Patton, E Elizabeth.

Development ; 142(4): 620-32, 2015 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-25670789

8.

Cell signalling: Red alert about lipid's role in skin cancer.

Jackson, Ian J; Patton, E Elizabeth.

Nature ; 549(7672): 337-339, 2017 09 21.

Artículo en Inglés | MEDLINE | ID: mdl-28869972

9.

Cross-species models of human melanoma.

van der Weyden, Louise; Patton, E Elizabeth; Wood, Geoffrey A; Foote, Alastair K; Brenn, Thomas; Arends, Mark J; Adams, David J.

J Pathol ; 238(2): 152-65, 2016 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-26354726

10.

DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans.

Longman, Dasa; Hug, Nele; Keith, Marianne; Anastasaki, Corina; Patton, E Elizabeth; Grimes, Graeme; Cáceres, Javier F.

Nucleic Acids Res ; 41(17): 8319-31, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23828042

11.

Differentiated melanocyte cell division occurs in vivo and is promoted by mutations in Mitf.

Taylor, Kerrie L; Lister, James A; Zeng, Zhiqiang; Ishizaki, Hironori; Anderson, Caroline; Kelsh, Robert N; Jackson, Ian J; Patton, E Elizabeth.

Development ; 138(16): 3579-89, 2011 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-21771814

12.

Cancer: Trouble upstream.

Patton, E Elizabeth; Harrington, Lea.

Nature ; 495(7441): 320-1, 2013 Mar 21.

Artículo en Inglés | MEDLINE | ID: mdl-23518559

13.

The melanocyte lineage in development and disease.

Mort, Richard L; Jackson, Ian J; Patton, E Elizabeth.

Development ; 142(7): 1387, 2015 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-25804742

14.

Live imaging in zebrafish reveals neu(trophil) insight into the metastatic niche.

Patton, E Elizabeth.

J Pathol ; 227(4): 381-4, 2012 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-22611003

15.

Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish.

Anastasaki, Corina; Longman, Dasa; Capper, Amy; Patton, E Elizabeth; Cáceres, Javier F.

Nucleic Acids Res ; 39(9): 3686-94, 2011 May.

Artículo en Inglés | MEDLINE | ID: mdl-21227923

16.

Adult zebrafish as advanced models of human disease.

White, Richard M; Patton, E Elizabeth.

Dis Model Mech ; 16(8)2023 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-37522272

17.

Acetylation reprograms MITF target selectivity and residence time.

Louphrasitthiphol, Pakavarin; Loffreda, Alessia; Pogenberg, Vivian; Picaud, Sarah; Schepsky, Alexander; Friedrichsen, Hans; Zeng, Zhiqiang; Lashgari, Anahita; Thomas, Benjamin; Patton, E Elizabeth; Wilmanns, Matthias; Filippakopoulos, Panagis; Lambert, Jean-Philippe; Steingrímsson, Eiríkur; Mazza, Davide; Goding, Colin R.

Nat Commun ; 14(1): 6051, 2023 09 28.

Artículo en Inglés | MEDLINE | ID: mdl-37770430

18.

PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma.

Polubothu, Satyamaanasa; Bender, Nicole; Muthiah, Siobhan; Zecchin, Davide; Demetriou, Charalambos; Martin, Sara Barberan; Malhotra, Sony; Travnickova, Jana; Zeng, Zhiqiang; Böhm, Markus; Barbarot, Sebastien; Cottrell, Catherine; Davies, Olivia; Baselga, Eulalia; Burrows, Nigel P; Carmignac, Virginie; Diaz, Joey Santiago; Fink, Christine; Haenssle, Holger A; Happle, Rudolf; Harland, Mark; Majerowski, Jacquelyn; Vabres, Pierre; Vincent, Marie; Newton-Bishop, Julia A; Bishop, D Tim; Siegel, Dawn; Patton, E Elizabeth; Topf, Maya; Rajan, Neil; Drolet, Beth; Kinsler, Veronica A.

J Invest Dermatol ; 143(6): 1042-1051.e3, 2023 06.

Artículo en Inglés | MEDLINE | ID: mdl-36566878

19.

Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processes.

Shu, Xinhua; Zeng, Zhiqiang; Gautier, Philippe; Lennon, Alan; Gakovic, Milica; Patton, E Elizabeth; Wright, Alan F.

Hum Mol Genet ; 19(4): 657-70, 2010 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-19955120

20.

Long-term non-invasive drug treatments in adult zebrafish that lead to melanoma drug resistance.

Lu, Yuting; Patton, E Elizabeth.

Dis Model Mech ; 15(5)2022 05 01.

Artículo en Inglés | MEDLINE | ID: mdl-35394030

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Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution.

Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells.

Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish.

Spontaneously occurring melanoma in animals and their relevance to human melanoma.

BRAF/MAPK and GSK3 signaling converges to control MITF nuclear export.

Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish.

The melanocyte lineage in development and disease.

Cell signalling: Red alert about lipid's role in skin cancer.

Cross-species models of human melanoma.

DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans.

Differentiated melanocyte cell division occurs in vivo and is promoted by mutations in Mitf.

Cancer: Trouble upstream.

The melanocyte lineage in development and disease.

Live imaging in zebrafish reveals neu(trophil) insight into the metastatic niche.

Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish.

Adult zebrafish as advanced models of human disease.

Acetylation reprograms MITF target selectivity and residence time.

PTPN11 Mosaicism Causes a Spectrum of Pigmentary and Vascular Neurocutaneous Disorders and Predisposes to Melanoma.

Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processes.

Long-term non-invasive drug treatments in adult zebrafish that lead to melanoma drug resistance.