Detalles de la búsqueda
1.
Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer's disease.
Bioorg Med Chem
; 71: 116952, 2022 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35930852
2.
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases.
Neurochem Res
; 45(12): 3003-3020, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33079324
3.
Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease.
Molecules
; 25(14)2020 Jul 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32664425
4.
Curcumin and Heme Oxygenase: Neuroprotection and Beyond.
Int J Mol Sci
; 20(10)2019 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-31100781
5.
Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer's Disease.
Molecules
; 23(8)2018 Jul 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-30061534
6.
The Keap1/Nrf2-ARE Pathway as a Pharmacological Target for Chalcones.
Molecules
; 23(7)2018 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30037040
7.
Naturally Inspired Molecules as Multifunctional Agents for Alzheimer's Disease Treatment.
Molecules
; 21(5)2016 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-27196880
8.
Antioxidant and Anti-Melanogenesis Effects of Teucrium chamaedrys L. Cell Suspension Extract and Its Main Phenylethanoid Glycoside in B16-F10 Cells.
Plants (Basel)
; 13(6)2024 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38592786
9.
A novel arylpiperazine derivative (LQFM181) protects against neurotoxicity induced by 3- nitropropionic acid in in vitro and in vivo models.
Chem Biol Interact
; 395: 111026, 2024 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38679115
10.
Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions.
J Clin Med
; 12(3)2023 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36769818
11.
PROTAC-Induced Glycogen Synthase Kinase 3ß Degradation as a Potential Therapeutic Strategy for Alzheimer's Disease.
ACS Chem Neurosci
; 14(11): 1963-1970, 2023 06 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37218653
12.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.
Eur J Med Chem
; 252: 115297, 2023 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36996713
13.
Protective effects of chrysin against the neurotoxicity induced by aluminium: In vitro and in vivo studies.
Toxicology
; 465: 153033, 2022 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34774662
14.
Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
RSC Med Chem
; 13(5): 568-584, 2022 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-35694691
15.
Esculetin Provides Neuroprotection against Mutant Huntingtin-Induced Toxicity in Huntington's Disease Models.
Pharmaceuticals (Basel)
; 14(10)2021 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34681268
16.
Esculetin as a Bifunctional Antioxidant Prevents and Counteracts the Oxidative Stress and Neuronal Death Induced by Amyloid Protein in SH-SY5Y Cells.
Antioxidants (Basel)
; 9(6)2020 Jun 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-32630394
17.
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3ß Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease.
ACS Chem Neurosci
; 11(17): 2728-2740, 2020 09 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32663009
18.
Optimization of the Extraction from Spent Coffee Grounds Using the Desirability Approach.
Antioxidants (Basel)
; 9(5)2020 Apr 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-32365615
19.
Design and synthesis of H2S-donor hybrids: A new treatment for Alzheimer's disease?
Eur J Med Chem
; 184: 111745, 2019 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31585237
20.
PQM130, a Novel Feruloyl-Donepezil Hybrid Compound, Effectively Ameliorates the Cognitive Impairments and Pathology in a Mouse Model of Alzheimer's Disease.
Front Pharmacol
; 10: 658, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31244664