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Clin Rheumatol ; 22(2): 143-5, 2003 May.
Artículo en Inglés | MEDLINE | ID: mdl-12740681

RESUMEN

A19-year-old woman presented with pain and tenderness in both calves associated with pyrexia and neutrophil leukocytosis. Gastrocnemius muscle biopsy showed a non-specific lymphocytic myositis and she was found to have positive c-ANCA, in the absence of other evidence of systemic vasculitis. Subsequent investigation of her gastrointestinal tract revealed extensive Crohn's disease. The myositis responded promptly to treatment with prednisolone 0.5 mg/kg. A review of the literature showed that localised calf pain in the setting of Crohn's disease can be caused by non-specific myositis, granulomatous myositis or vasculitis. It is proposed that the "gastrocnemius myalgia syndrome" be included in the typical - albeit rare - extraintestinal manifestations that may herald the appearance of inflammatory bowel disease.


Asunto(s)
Antiinflamatorios/uso terapéutico , Enfermedad de Crohn/complicaciones , Músculo Esquelético/patología , Miositis/tratamiento farmacológico , Miositis/etiología , Prednisolona/uso terapéutico , Adulto , Anticuerpos Anticitoplasma de Neutrófilos/inmunología , Enfermedad de Crohn/diagnóstico , Enfermedad de Crohn/inmunología , Femenino , Humanos , Miositis/inmunología
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