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1.
Br J Haematol ; 200(3): 353-357, 2023 02.
Artículo en Inglés | MEDLINE | ID: mdl-36198407

RESUMEN

Intravenous Anti-Rhesus-D immunoglobulin (Anti-D) is a first-line treatment option for immune thrombocytopenia in non-splenectomised and RhD-positive patients. In this report, we retrospectively review our experience with intramuscular (IM) Anti-D treatment in 74 adult patients between 1990 and 2018. We found that 73% of patients showed a response; almost all of them had complete responses (68.9%), and 26% achieved complete responses sustained at least 6 months after treatment discontinuation. [Correction added on 02 December 2022, after first online publication: In the preceding sentence, '(68.89%)' has been corrected to '(68.9%)' in this version.] No significant side effects were observed with no cases of acute haemolysis or anaemia reported. We conclude from this study that IM Anti-D is an effective and safe treatment for immune thrombocytopenia.


Asunto(s)
Púrpura Trombocitopénica Idiopática , Trombocitopenia , Adulto , Humanos , Púrpura Trombocitopénica Idiopática/tratamiento farmacológico , Estudios Retrospectivos , Globulina Inmune rho(D) , Trombocitopenia/tratamiento farmacológico
4.
Rev. colomb. cancerol ; 25(1): 56-60, ene.-mar. 2021. tab, graf
Artículo en Español | LILACS | ID: biblio-1289199

RESUMEN

Resumen Los pacientes diagnosticados de adenocarcinoma gástrico pueden desarrollar metástasis hepáticas o carcinomatosis peritoneal, pero la presencia de metástasis musculares es extremadamente infrecuente, con muy pocos casos descritos. Presentamos a una paciente de 44 años con una tumoración dolorosa en miembro superior izquierdo. Fue tratada un año antes de un adenocarcinoma gástrico con cirugía y quimioterapia. Mediante pruebas de imagen y biopsia, se le diagnosticó metástasis muscular única de adenocarcinoma gástrico, siendo intervenida realizando exéresis quirúrgica.


Abstract Patients diagnosed with gastric adenocarcinoma may develop liver metastases or peritoneal carcinomatosis, but the presence of muscle metastases is extremely rare, with very few cases reported. We present a 44-year-old female patient with a painful tumor in her left upper limb. She was treated with surgery and chemotherapy for gastric adenocarcinoma a year before. By imaging tests and biopsy, she was diagnosed with a single muscle metastasis from gastric adenocarcinoma and underwent surgical exeresis.


Asunto(s)
Femenino , Adulto , Adenocarcinoma , Músculo Esquelético , Metástasis de la Neoplasia , Neoplasias Peritoneales , Informe de Investigación , Literatura
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