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1.

Improvements in Survival and Clinical Benefit With Gemcitabine as First-Line Therapy for Patients With Advanced Pancreas Cancer: A Randomized Trial.

Burris, H A; Moore, M J; Andersen, J; Green, M R; Rothenberg, M L; Modiano, M R; Cripps, M C; Portenoy, R K; Storniolo, A M; Tarassoff, P; Nelson, R; Dorr, F A; Stephens, C D; Von Hoff, D D.

J Clin Oncol ; 41(36): 5482-5492, 2023 12 20.

Artículo en Inglés | MEDLINE | ID: mdl-38100992

2.

Pragmatic randomized clinical trials: a proposal to enhance evaluation of new cancer therapies with early signs of exceptional activity.

Koehler, M; Donnelly, E T; Kalanovic, D; Dagher, R; Rothenberg, M L.

Ann Oncol ; 27(7): 1342-8, 2016 07.

Artículo en Inglés | MEDLINE | ID: mdl-27029709

3.

Multicenter phase II trial of adjuvant therapy for resected pancreatic cancer using cisplatin, 5-fluorouracil, and interferon-alfa-2b-based chemoradiation: ACOSOG Trial Z05031.

Picozzi, V J; Abrams, R A; Decker, P A; Traverso, W; O'Reilly, E M; Greeno, E; Martin, R C; Wilfong, L S; Rothenberg, M L; Posner, M C; Pisters, P W T.

Ann Oncol ; 22(2): 348-54, 2011 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-20670978

4.

Incidence and evolution of oxaliplatin-induced peripheral sensory neuropathy in diabetic patients with colorectal cancer: a pooled analysis of three phase III studies.

Ramanathan, R K; Rothenberg, M L; de Gramont, A; Tournigand, C; Goldberg, R M; Gupta, S; André, T.

Ann Oncol ; 21(4): 754-758, 2010 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-19887466

5.

Capecitabine plus oxaliplatin (XELOX) versus 5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX-4) as second-line therapy in metastatic colorectal cancer: a randomized phase III noninferiority study.

Rothenberg, M L; Cox, J V; Butts, C; Navarro, M; Bang, Y-J; Goel, R; Gollins, S; Siu, L L; Laguerre, S; Cunningham, D.

Ann Oncol ; 19(10): 1720-6, 2008 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-18550577

6.

Phase I trial of oral MAC-321 in subjects with advanced malignant solid tumors.

Lockhart, A C; Bukowski, R; Rothenberg, M L; Wang, K K; Cooper, W; Grover, J; Appleman, L; Mayer, P R; Shapiro, M; Zhu, A X.

Cancer Chemother Pharmacol ; 60(2): 203-9, 2007 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-17091249

7.

High-dose carboplatin with diethyldithiocarbamate chemoprotection in treatment of women with relapsed ovarian cancer.

Rothenberg, M L; Ostchega, Y; Steinberg, S M; Young, R C; Hummel, S; Ozols, R F.

J Natl Cancer Inst ; 80(18): 1488-92, 1988 Nov 16.

Artículo en Inglés | MEDLINE | ID: mdl-2846858

8.

Matrix metalloproteinases: biologic activity and clinical implications.

Nelson, A R; Fingleton, B; Rothenberg, M L; Matrisian, L M.

J Clin Oncol ; 18(5): 1135-49, 2000 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-10694567

9.

Dose-intensive induction therapy with cyclophosphamide, cisplatin, and consolidative abdominal radiation in advanced-stage epithelial ovarian cancer.

Rothenberg, M L; Ozols, R F; Glatstein, E; Steinberg, S M; Reed, E; Young, R C.

J Clin Oncol ; 10(5): 727-34, 1992 May.

Artículo en Inglés | MEDLINE | ID: mdl-1569445

10.

Mortality associated with irinotecan plus bolus fluorouracil/leucovorin: summary findings of an independent panel.

Rothenberg, M L; Meropol, N J; Poplin, E A; Van Cutsem, E; Wadler, S.

J Clin Oncol ; 19(18): 3801-7, 2001 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-11559717

11.

Commentary concerning demonstration of safety and efficacy of investigational anticancer agents in clinical trials.

O'Shaughnessy, J A; Wittes, R E; Burke, G; Friedman, M A; Johnson, J R; Niederhuber, J E; Rothenberg, M L; Woodcock, J; Chabner, B A; Temple, R.

J Clin Oncol ; 9(12): 2225-32, 1991 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-1960563

12.

Phase I and pharmacokinetic trial of weekly CPT-11.

Rothenberg, M L; Kuhn, J G; Burris, H A; Nelson, J; Eckardt, J R; Tristan-Morales, M; Hilsenbeck, S G; Weiss, G R; Smith, L S; Rodriguez, G I.

J Clin Oncol ; 11(11): 2194-204, 1993 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-8229134

13.

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.

Burris, H A; Moore, M J; Andersen, J; Green, M R; Rothenberg, M L; Modiano, M R; Cripps, M C; Portenoy, R K; Storniolo, A M; Tarassoff, P; Nelson, R; Dorr, F A; Stephens, C D; Von Hoff, D D.

J Clin Oncol ; 15(6): 2403-13, 1997 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-9196156

14.

Phase I and pharmacokinetic trial of oral irinotecan administered daily for 5 days every 3 weeks in patients with solid tumors.

Drengler, R L; Kuhn, J G; Schaaf, L J; Rodriguez, G I; Villalona-Calero, M A; Hammond, L A; Stephenson, J A; Hodges, S; Kraynak, M A; Staton, B A; Elfring, G L; Locker, P K; Miller, L L; Von Hoff, D D; Rothenberg, M L.

J Clin Oncol ; 17(2): 685-96, 1999 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-10080615

15.

Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer.

Rothenberg, M L; Eckardt, J R; Kuhn, J G; Burris, H A; Nelson, J; Hilsenbeck, S G; Rodriguez, G I; Thurman, A M; Smith, L S; Eckhardt, S G; Weiss, G R; Elfring, G L; Rinaldi, D A; Schaaf, L J; Von Hoff, D D.

J Clin Oncol ; 14(4): 1128-35, 1996 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-8648367

16.

A phase I and translational study of sequential administration of the topoisomerase I and II inhibitors topotecan and etoposide.

Hammond, L A; Eckardt, J R; Ganapathi, R; Burris, H A; Rodriguez, G A; Eckhardt, S G; Rothenberg, M L; Weiss, G R; Kuhn, J G; Hodges, S; Von Hoff, D D; Rowinsky, E K.

Clin Cancer Res ; 4(6): 1459-67, 1998 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-9626463

17.

Phase I and pharmacokinetic study of GI147211, a water-soluble camptothecin analogue, administered for five consecutive days every three weeks.

Eckhardt, S G; Baker, S D; Eckardt, J R; Burke, T G; Warner, D L; Kuhn, J G; Rodriguez, G; Fields, S; Thurman, A; Smith, L; Rothenberg, M L; White, L; Wissel, P; Kunka, R; DePee, S; Littlefield, D; Burris, H A; Von Hoff, D D; Rowinsky, E K.

Clin Cancer Res ; 4(3): 595-604, 1998 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-9533526

18.

The role of nonrandomized trials in the evaluation of oncology drugs.

Simon, R; Blumenthal, G M; Rothenberg, M L; Sommer, J; Roberts, S A; Armstrong, D K; LaVange, L M; Pazdur, R.

Clin Pharmacol Ther ; 97(5): 502-7, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25676488

19.

CPT-11: an original spectrum of clinical activity.

Rothenberg, M L.

Semin Oncol ; 23(1 Suppl 3): 21-6, 1996 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-8633249

20.

Efficacy and toxicity of irinotecan in patients with colorectal cancer.