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1.

Mutational profile of previously treated chronic lymphocytic leukemia patients progressing on acalabrutinib or ibrutinib.

Woyach, Jennifer A; Jones, Daniel; Jurczak, Wojciech; Robak, Tadeusz; Illes, Arpad; Kater, Arnon P; Ghia, Paolo; Byrd, John C; Seymour, John F; Long, Susan; Mohamed, Nehad; Benrashid, Samon; Lai, Tzung-Huei; De Jesus, Gary; Lai, Richard; de Bruin, Gerjan; Rule, Simon; Munugalavadla, Veerendra.

Blood ; 2024 May 16.

Artículo en Inglés | MEDLINE | ID: mdl-38754046

2.

Analysis of ventricular arrhythmias and sudden death from prospective, randomized clinical trials of acalabrutinib.

Sharman, Jeff P; Ghia, Paolo; Miranda, Paulo; Bajwa, Naghmana; Rule, Simon; Shaw, Bob; Seymour, John F.

Br J Haematol ; 2024 Apr 17.

Artículo en Inglés | MEDLINE | ID: mdl-38634256

3.

Ibrutinib, obinutuzumab, and venetoclax in relapsed and untreated patients with mantle cell lymphoma: a phase 1/2 trial.

Le Gouill, Steven; Morschhauser, Franck; Chiron, David; Bouabdallah, Krimo; Cartron, Guillaume; Casasnovas, Olivier; Bodet-Milin, Caroline; Ragot, Sylviane; Bossard, Céline; Nadal, Nathalie; Herbaux, Charles; Tessoulin, Benoit; Tchernonog, Emmanuelle; Rossi, Cédric; McCulloch, Rory; Gastinne, Thomas; Callanan, Mary B; Rule, Simon.

Blood ; 137(7): 877-887, 2021 02 18.

Artículo en Inglés | MEDLINE | ID: mdl-33181832

4.

Efficacy and safety assessment of prolonged maintenance with subcutaneous rituximab in patients with relapsed or refractory indolent non-Hodgkin lymphoma: results of the phase III MabCute study.

Rule, Simon; Barreto, Wolney Gois; Briones, Javier; Carella, Angelo M; Casasnovas, Olivier; Pocock, Chris; Wendtner, Clemens-Martin; Zaja, Francesco; Robson, Susan; MacGregor, Lachlan; Tschopp, Roger R; Nick, Sonja; Dreyling, Martin.

Haematologica ; 107(2): 500-509, 2022 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-34134469

5.

The 5-year follow-up of a real-world observational study of patients in the United Kingdom and Ireland receiving ibrutinib for relapsed/refractory mantle cell lymphoma.

Tucker, David; Morley, Nick; MacLean, Peter; Vandenberghe, Elisabeth; Booth, Stephen; Parisi, Lori; Rule, Simon.

Br J Haematol ; 192(6): 1035-1038, 2021 03.

Artículo en Inglés | MEDLINE | ID: mdl-32445482

6.

Ibrutinib for mantle cell lymphoma at first relapse: a United Kingdom real-world analysis of outcomes in 211 patients.

McCulloch, Rory; Lewis, David; Crosbie, Nicola; Eyre, Toby A; Bolam, Simon; Arasaretnam, Anita; Creasey, Thomas; Goradia, Harshita; McMillan, Annabel; Dawi, Safia; Harrison, Samuel; Miles, Oliver; Robinson, Andrew; Dutton, David; Wilson, Matthew R; McKay, Pam; Follows, George; Phillips, Neil; Patmore, Russell; Lambert, Jonathan; Bishton, Mark; Osborne, Wendy; Johnston, Rosalynd; Kirkwood, Amy A; Rule, Simon.

Br J Haematol ; 193(2): 290-298, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-33620106

7.

The UK NCRI study of chlorambucil, mitoxantrone and dexamethasone (CMD) versus fludarabine, mitoxantrone and dexamethasone (FMD) for untreated advanced stage follicular lymphoma: molecular response strongly predicts prolonged overall survival.

Bishton, Mark J; Rule, Simon; Wilson, William; Turner, Deborah; Patmore, Russell; Clifton-Hadley, Laura; McMillan, Andrew; Lush, Richard; Haynes, Andrew.

Br J Haematol ; 190(4): 545-554, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-32150649

8.

Efficacy of R-BAC in relapsed, refractory mantle cell lymphoma post BTK inhibitor therapy.

McCulloch, Rory; Visco, Carlo; Eyre, Toby A; Frewin, Rebecca; Phillips, Neil; Tucker, David L; Quaglia, Francesca M; McMillan, Annabel; Lambert, Jonathan; Crosbie, Nicola; Rule, Simon.

Br J Haematol ; 189(4): 684-688, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32011729

9.

Blastoid and pleomorphic mantle cell lymphoma: still a diagnostic and therapeutic challenge!

Dreyling, Martin; Klapper, Wolfram; Rule, Simon.

Blood ; 132(26): 2722-2729, 2018 12 27.

Artículo en Inglés | MEDLINE | ID: mdl-30385481

10.

Allogeneic stem cell transplantation as part of front line therapy for Mantle cell lymphoma.

Rule, Simon; Cook, Gordon; Russell, Nigel H; Hunter, Ann; Robinson, Stephen; Morley, Nick; Sureda, Anna; Patrick, Pip; Clifton-Hadley, Laura; Adedayo, Toyin; Kirkwood, Amy; Peggs, Karl S.

Br J Haematol ; 184(6): 999-1005, 2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30560573

11.

Incidence of and risk factors for major haemorrhage in patients treated with ibrutinib: An integrated analysis.

Brown, Jennifer R; Moslehi, Javid; Ewer, Michael S; O'Brien, Susan M; Ghia, Paolo; Cymbalista, Florence; Shanafelt, Tait D; Fraser, Graeme; Rule, Simon; Coutre, Steven E; Dilhuydy, Marie-Sarah; Cramer, Paula; Jaeger, Ulrich; Dreyling, Martin; Byrd, John C; Treon, Steven; Liu, Emily Y; Chang, Stephen; Bista, Amulya; Vempati, Rama; Boornazian, Lisa; Valentino, Rudolph; Reddy, Vijay; Mahler, Michelle; Yang, Huiying; Graef, Thorsten; Burger, Jan A.

Br J Haematol ; 184(4): 558-569, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30506764

12.

Acalabrutinib in relapsed or refractory mantle cell lymphoma (ACE-LY-004): a single-arm, multicentre, phase 2 trial.

Wang, Michael; Rule, Simon; Zinzani, Pier Luigi; Goy, Andre; Casasnovas, Olivier; Smith, Stephen D; Damaj, Gandhi; Doorduijn, Jeanette; Lamy, Thierry; Morschhauser, Franck; Panizo, Carlos; Shah, Bijal; Davies, Andrew; Eek, Richard; Dupuis, Jehan; Jacobsen, Eric; Kater, Arnon P; Le Gouill, Steven; Oberic, Lucie; Robak, Taduesz; Covey, Todd; Dua, Richa; Hamdy, Ahmed; Huang, Xin; Izumi, Raquel; Patel, Priti; Rothbaum, Wayne; Slatter, J Greg; Jurczak, Wojciech.

Lancet ; 391(10121): 659-667, 2018 02 17.

Artículo en Inglés | MEDLINE | ID: mdl-29241979

13.

Final results and overall survival data from a phase II study of acalabrutinib monotherapy in patients with relapsed/refractory mantle cell lymphoma, including those with poor prognostic factors.

Le Gouill, Steven; Dlugosz-Danecka, Monika; Rule, Simon; Zinzani, Pier Luigi; Goy, Andre; Smith, Stephen D; Doorduijn, Jeanette K; Panizo, Carlos; Shah, Bijal D; Davies, Andrew J; Eek, Richard; Jacobsen, Eric; Kater, Arnon P; Robak, Tadeusz; Jain, Preetesh; Calvo, Roser; Tao, Lin; Wang, Michael.

Haematologica ; 109(1): 343-350, 2024 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-37470152

14.

The modern approach to mantle cell lymphoma.

Rule, Simon.

Hematol Oncol ; 37 Suppl 1: 66-69, 2019 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-31187531

15.

A phase II study to assess the safety and efficacy of the dual mTORC1/2 inhibitor vistusertib in relapsed, refractory DLBCL.

Eyre, Toby A; Hildyard, Catherine; Hamblin, Angela; Ali, Ayesha S; Houlton, Aimee; Hopkins, Louise; Royston, Daniel; Linton, Kim M; Pettitt, Andrew; Rule, Simon; Cwynarski, Kate; Barrington, Sally F; Warbey, Victoria; Wrench, David; Barrans, Sharon; Hirst, Caroline S; Panchal, Anesh; Roudier, Martine P; Harrington, Elizabeth A; Davies, Andrew; Collins, Graham P.

Hematol Oncol ; 37(4): 352-359, 2019 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-31385336

16.

Systemic Exposure of Rituximab Increased by Ibrutinib: Pharmacokinetic Results and Modeling Based on the HELIOS Trial.

Lavezzi, Silvia Maria; de Jong, Jan; Neyens, Martine; Cramer, Paula; Demirkan, Fatih; Fraser, Graeme; Bartlett, Nancy; Dilhuydy, Marie-Sarah; Loscertales, Javier; Avigdor, Abraham; Rule, Simon; Samoilova, Olga; Goy, Andre; Ganguly, Siddhartha; Salman, Mariya; Howes, Angela; Mahler, Michelle; De Nicolao, Giuseppe; Poggesi, Italo.

Pharm Res ; 36(7): 93, 2019 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-31044267

17.

Prospective subgroup analyses of the randomized MCL-002 (SPRINT) study: lenalidomide versus investigator's choice in relapsed or refractory mantle cell lymphoma.

Arcaini, Luca; Lamy, Thierry; Walewski, Jan; Belada, David; Mayer, Jiri; Radford, John; Jurczak, Wojciech; Morschhauser, Franck; Alexeeva, Julia; Rule, Simon; Cabeçadas, José; Campo, Elias; Pileri, Stefano A; Biyukov, Tsvetan; Patturajan, Meera; Casadebaig Bravo, Marie-Laure; Trnený, Marek.

Br J Haematol ; 180(2): 224-235, 2018 01.

Artículo en Inglés | MEDLINE | ID: mdl-29193019

18.

A phase 1 clinical trial of the selective BTK inhibitor ONO/GS-4059 in relapsed and refractory mature B-cell malignancies.

Walter, Harriet S; Rule, Simon A; Dyer, Martin J S; Karlin, Lionel; Jones, Ceri; Cazin, Bruno; Quittet, Philippe; Shah, Nimish; Hutchinson, Claire V; Honda, Hideyuki; Duffy, Kevin; Birkett, Joseph; Jamieson, Virginia; Courtenay-Luck, Nigel; Yoshizawa, Toshio; Sharpe, John; Ohno, Tomoya; Abe, Shinichiro; Nishimura, Akihisa; Cartron, Guillaume; Morschhauser, Franck; Fegan, Christopher; Salles, Gilles.

Blood ; 127(4): 411-9, 2016 Jan 28.

Artículo en Inglés | MEDLINE | ID: mdl-26542378

19.

Postibrutinib outcomes in patients with mantle cell lymphoma.

Martin, Peter; Maddocks, Kami; Leonard, John P; Ruan, Jia; Goy, Andre; Wagner-Johnston, Nina; Rule, Simon; Advani, Ranjana; Iberri, David; Phillips, Tycel; Spurgeon, Stephen; Kozin, Eliana; Noto, Katherine; Chen, Zhengming; Jurczak, Wojciech; Auer, Rebecca; Chmielowska, Ewa; Stilgenbauer, Stephan; Bloehdorn, Johannes; Portell, Craig; Williams, Michael E; Dreyling, Martin; Barr, Paul M; Chen-Kiang, Selina; DiLiberto, Maurizio; Furman, Richard R; Blum, Kristie A.

Blood ; 127(12): 1559-63, 2016 Mar 24.

Artículo en Inglés | MEDLINE | ID: mdl-26764355

20.

Outcomes in 370 patients with mantle cell lymphoma treated with ibrutinib: a pooled analysis from three open-label studies.

Rule, Simon; Dreyling, Martin; Goy, Andre; Hess, Georg; Auer, Rebecca; Kahl, Brad; Cavazos, Nora; Liu, Black; Yang, Shiyi; Clow, Fong; Goldberg, Jenna D; Beaupre, Darrin; Vermeulen, Jessica; Wildgust, Mark; Wang, Michael.

Br J Haematol ; 179(3): 430-438, 2017 11.

Artículo en Inglés | MEDLINE | ID: mdl-28832957

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