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1.

British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma.

Rushbrook, Simon M; Kendall, Timothy James; Zen, Yoh; Albazaz, Raneem; Manoharan, Prakash; Pereira, Stephen P; Sturgess, Richard; Davidson, Brian R; Malik, Hassan Z; Manas, Derek; Heaton, Nigel; Prasad, K Raj; Bridgewater, John; Valle, Juan W; Goody, Rebecca; Hawkins, Maria; Prentice, Wendy; Morement, Helen; Walmsley, Martine; Khan, Shahid A.

Gut ; 73(1): 16-46, 2023 Dec 07.

Artículo en Inglés | MEDLINE | ID: mdl-37770126

2.

The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis.

Barron-Millar, Ben; Ogle, Laura; Mells, George; Flack, Steven; Badrock, Jonathan; Sandford, Richard; Kirby, John; Palmer, Jeremy; Jopson, Laura; Brain, John; Smith, Graham R; Rushton, Steve; Hegade, Vinod S; Jones, Rebecca; Rushbrook, Simon; Thorburn, Douglas; Ryder, Steve; Hirschfield, Gideon; Dyson, Jessica K; Jones, David E J.

Hepatology ; 74(6): 3269-3283, 2021 12.

Artículo en Inglés | MEDLINE | ID: mdl-34129689

3.

Intestinal Microbiome-Macrophage Crosstalk Contributes to Cholestatic Liver Disease by Promoting Intestinal Permeability in Mice.

Isaacs-Ten, Anna; Echeandia, Marta; Moreno-Gonzalez, Mar; Brion, Arlaine; Goldson, Andrew; Philo, Mark; Patterson, Angela M; Parker, Aimee; Galduroz, Mikel; Baker, David; Rushbrook, Simon M; Hildebrand, Falk; Beraza, Naiara.

Hepatology ; 72(6): 2090-2108, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-32168395

4.

A randomized, placebo-controlled, phase II study of obeticholic acid for primary sclerosing cholangitis.

Kowdley, Kris V; Vuppalanchi, Raj; Levy, Cynthia; Floreani, Annarosa; Andreone, Pietro; LaRusso, Nicholas F; Shrestha, Roshan; Trotter, James; Goldberg, David; Rushbrook, Simon; Hirschfield, Gideon M; Schiano, Thomas; Jin, Yuying; Pencek, Richard; MacConell, Leigh; Shapiro, David; Bowlus, Christopher L.

J Hepatol ; 73(1): 94-101, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32165251

5.

The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS-9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis.

Trauner, Michael; Gulamhusein, Aliya; Hameed, Bilal; Caldwell, Stephen; Shiffman, Mitchell L; Landis, Charles; Eksteen, Bertus; Agarwal, Kosh; Muir, Andrew; Rushbrook, Simon; Lu, Xiaomin; Xu, Jun; Chuang, Jen-Chieh; Billin, Andrew N; Li, Georgia; Chung, Chuhan; Subramanian, G Mani; Myers, Robert P; Bowlus, Christopher L; Kowdley, Kris V.

Hepatology ; 70(3): 788-801, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-30661255

6.

Fine-Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease.

Blokker, Britt A; Maijo, Monica; Echeandia, Marta; Galduroz, Mikel; Patterson, Angela M; Ten, Anna; Philo, Mark; Schungel, Rebecca; Gutierrez-de Juan, Virginia; Halilbasic, Emina; Fuchs, Claudia; Le Gall, Gwenaelle; Milkiewicz, Malgorzata; Milkiewicz, Piotr; Banales, Jesus M; Rushbrook, Simon M; Mato, José M; Trauner, Michael; Müller, Michael; Martínez-Chantar, María Luz; Varela-Rey, Marta; Beraza, Naiara.

Hepatology ; 69(2): 699-716, 2019 02.

Artículo en Inglés | MEDLINE | ID: mdl-30229970

7.

Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System.

Goode, Elizabeth C; Clark, Allan B; Mells, George F; Srivastava, Brijesh; Spiess, Kelly; Gelson, William T H; Trivedi, Palak J; Lynch, Kate D; Castren, Edit; Vesterhus, Mette N; Karlsen, Tom H; Ji, Sun-Gou; Anderson, Carl A; Thorburn, Douglas; Hudson, Mark; Heneghan, Michael A; Aldersley, Mark A; Bathgate, Andrew; Sandford, Richard N; Alexander, Graeme J; Chapman, Roger W; Walmsley, Martine; Hirschfield, Gideon M; Rushbrook, Simon M.

Hepatology ; 69(5): 2120-2135, 2019 05.

Artículo en Inglés | MEDLINE | ID: mdl-30566748

8.

British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis.

Chapman, Michael Huw; Thorburn, Douglas; Hirschfield, Gideon M; Webster, George G J; Rushbrook, Simon M; Alexander, Graeme; Collier, Jane; Dyson, Jessica K; Jones, David Ej; Patanwala, Imran; Thain, Collette; Walmsley, Martine; Pereira, Stephen P.

Gut ; 68(8): 1356-1378, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-31154395

9.

n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD.

Vauzour, David; Rodriguez-Ramiro, Ildefonso; Rushbrook, Simon; Ipharraguerre, Ignacio R; Bevan, Damon; Davies, Susan; Tejera, Noemi; Mena, Pedro; de Pascual-Teresa, Sonia; Del Rio, Daniele; Gavrilovic, Jelena; Minihane, Anne Marie.

Biochim Biophys Acta Mol Basis Dis ; 1864(1): 69-78, 2018 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-28986308

10.

Reply.

Goode, Elizabeth C; Hirschfield, Gideon M; Rushbrook, Simon M.

Hepatology ; 71(1): 399-400, 2020 01.

Artículo en Inglés | MEDLINE | ID: mdl-31550385

11.

A Mechanistic Insight Into the Role of Gut Microbiota in the Pathogenesis of Primary Sclerosing Cholangitis.

Patel, Meha; Watson, Alastair J M; Rushbrook, Simon.

Gastroenterology ; 157(6): 1686-1688, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31614124

12.

Lansoprazole-induced acute lung and liver injury: a case report.

Atkins, Christopher; Maheswaran, Tina; Rushbrook, Simon; Kamath, Ajay.

Int J Clin Pharmacol Ther ; 52(12): 1102-4, 2014 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-25373140

13.

Î³-H2AX+CD8+ T lymphocytes cannot respond to IFN-α, IL-2 or IL-6 in chronic hepatitis C virus infection.

Hoare, Matthew; Shankar, Arun; Shah, Meera; Rushbrook, Simon; Gelson, William; Davies, Susan; Akbar, Arne; Alexander, Graeme J M.

J Hepatol ; 58(5): 868-74, 2013 May.

Artículo en Inglés | MEDLINE | ID: mdl-23257612

14.

Bacterial and metabolic phenotypes associated with inadequate response to ursodeoxycholic acid treatment in primary biliary cholangitis.

Martinez-Gili, Laura; Pechlivanis, Alexandros; McDonald, Julie A K; Begum, Sofina; Badrock, Jonathan; Dyson, Jessica K; Jones, Rebecca; Hirschfield, Gideon; Ryder, Stephen D; Sandford, Richard; Rushbrook, Simon; Thorburn, Douglas; Taylor-Robinson, Simon D; Crossey, Mary M E; Marchesi, Julian R; Mells, George; Holmes, Elaine; Jones, David.

Gut Microbes ; 15(1): 2208501, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37191344

15.

Regulation of immune responses in primary biliary cholangitis: a transcriptomic analysis of peripheral immune cells.

Mulcahy, Victoria; Liaskou, Evaggelia; Martin, Jose-Ezequiel; Kotagiri, Prasanti; Badrock, Jonathan; Jones, Rebecca L; Rushbrook, Simon M; Ryder, Stephen D; Thorburn, Douglas; Taylor-Robinson, Simon D; Clark, Graeme; Cordell, Heather J; Sandford, Richard N; Jones, David E; Hirschfield, Gideon M; Mells, George F.

Hepatol Commun ; 7(4)2023 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-37026715

16.

Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis.

Han, Younghun; Byun, Jinyoung; Zhu, Catherine; Sun, Ryan; Roh, Julia Y; Cordell, Heather J; Lee, Hyun-Sung; Shaw, Vikram R; Kang, Sung Wook; Razjouyan, Javad; Cooley, Matthew A; Hassan, Manal M; Siminovitch, Katherine A; Folseraas, Trine; Ellinghaus, David; Bergquist, Annika; Rushbrook, Simon M; Franke, Andre; Karlsen, Tom H; Lazaridis, Konstantinos N; McGlynn, Katherine A; Roberts, Lewis R; Amos, Christopher I.

Nat Commun ; 14(1): 1069, 2023 02 24.

Artículo en Inglés | MEDLINE | ID: mdl-36828809

17.

APOBEC mutagenesis is a common process in normal human small intestine.

Wang, Yichen; Robinson, Philip S; Coorens, Tim H H; Moore, Luiza; Lee-Six, Henry; Noorani, Ayesha; Sanders, Mathijs A; Jung, Hyunchul; Katainen, Riku; Heuschkel, Robert; Brunton-Sim, Roxanne; Weston, Robyn; Read, Debbie; Nobbs, Beverley; Fitzgerald, Rebecca C; Saeb-Parsy, Kourosh; Martincorena, Iñigo; Campbell, Peter J; Rushbrook, Simon; Zilbauer, Matthias; Buczacki, Simon James Alexander; Stratton, Michael R.

Nat Genet ; 55(2): 246-254, 2023 02.

Artículo en Inglés | MEDLINE | ID: mdl-36702998

18.

An Unexpected Cause of Pancreatitis.

Kok, Khoon-Sheng; Wharton, Richard; Rushbrook, Simon M.

Gastroenterology ; 150(7): e5-e6, 2016 06.

Artículo en Inglés | MEDLINE | ID: mdl-27143591

19.

Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis.

Srivastava, Brijesh; Mells, George F; Cordell, Heather J; Muriithi, Agnes; Brown, Matthew; Ellinghaus, Eva; Franke, Andre; Karlsen, Tom H; Sandford, Richard N; Alexander, Graeme J; Chapman, Roger W; Rushbrook, Simon M; Melum, Espen.

Scand J Gastroenterol ; 47(7): 820-6, 2012 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-22554193

20.

The Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease.

Thomas, John P; Modos, Dezso; Rushbrook, Simon M; Powell, Nick; Korcsmaros, Tamas.

Front Immunol ; 13: 829525, 2022.

Artículo en Inglés | MEDLINE | ID: mdl-35185922

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