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1.
Rom J Intern Med ; 61(3): 167-174, 2023 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-37389671

RESUMEN

Carcinomatosis of the bone marrow is a rare clinical condition characterized by diffuse tumor infiltration of the bone marrow accompanied by hematological abnormalities, including thrombotic microangiopathy (TMA) and disseminated intravascular coagulation (DIC). In patients with gastric carcinoma, this association is infrequent. Below we present a case of a 19-year-old female patient with no known pathological history who presented with upper digestive tract bleeding. Upon examination, anemia and thrombocytopenia were documented, with schistocytes in the peripheral blood smear and prolonged coagulation times. Endoscopic studies indicated a lesion in the Borrmann IV gastric body, and the bone marrow biopsy showed the presence of signet ring cells. Because there was no possibility of systemic therapy, the patient died during hospitalization. This case contributes to the medical literature by describing an unusual presentation of a very frequent pathology.


Asunto(s)
Adenocarcinoma , Carcinoma , Coagulación Intravascular Diseminada , Neoplasias Gástricas , Microangiopatías Trombóticas , Femenino , Humanos , Adulto Joven , Adulto , Coagulación Intravascular Diseminada/etiología , Médula Ósea/patología , Adenocarcinoma/complicaciones , Microangiopatías Trombóticas/complicaciones , Microangiopatías Trombóticas/diagnóstico , Carcinoma/complicaciones , Carcinoma/tratamiento farmacológico , Carcinoma/patología , Neoplasias Gástricas/complicaciones
2.
Int J Surg Pathol ; 30(4): 419-421, 2022 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-34761696

RESUMEN

Objective. Reports of heterotopic tissue in the placenta are few and mainly include liver and adrenal cells. We report on adipose tissue found in the placenta. Case report. We present the case of a microscopic finding in a 25-year-old's placenta who suffered from hypertensive disorder in pregnancy. During routine microscopic study, we observed a heterotopic, benign, circumscribed and intervillous nodule of adipose tissue. Conclusion. To our knowledge, there is no other reported case of adipocytes among chorionic villi. Why foreign tissues show up in the placenta remains unknown; however, several new theories offer explanations.


Asunto(s)
Coristoma , Enfermedades Placentarias , Tejido Adiposo , Adulto , Femenino , Humanos , Hígado , Placenta , Embarazo
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