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1.
Nanotechnology ; 34(16)2023 Feb 09.
Artículo en Inglés | MEDLINE | ID: mdl-36689765

RESUMEN

Three dimensional magnetic textures are a cornerstone in magnetism research. In this work, we analyze the stabilization and dynamic response of a magnetic hopfion hosted in a toroidal nanoring with intrinsic Dzyaloshinskii-Moriya interaction simulating FeGe. Our results evidence that unlike their planar counterparts, where perpendicular magnetic anisotropies are necessary to stabilize hopfions, the shape anisotropy originated on the torus symmetry naturally yields the nucleation of these topological textures. We also analyze the magnetization dynamical response by applying a magnetic field pulse to differentiate among several magnetic patterns. Finally, to understand the nature of spin wave modes, we analyze the spatial distributions of the resonant mode amplitudes and phases and describe the differences among bulk and surface modes. Importantly, hopfions lying in toroidal nanorings present a non-circularly symmetric poloidal resonant mode, which is not observed in other systems hosting hopfions.

2.
Nanotechnology ; 35(6)2023 Nov 24.
Artículo en Inglés | MEDLINE | ID: mdl-38009501

RESUMEN

In this work, we present a theoretical model for domain wall (DW) oscillations in a curved magnetic nanowire with a constant curvature under the action of a uniaxial magnetic field. Our results show that the DW dynamics can be described as that of the mechanical pendulum, and both the NW curvature and the external magnetic field influence its oscillatory frequency. A comparison between our theoretical approach and experimental data in the literature shows an excellent agreement. The results presented here can be used to design devices demanding the proper control of the DW oscillatory motion in NWs.

3.
Nanotechnology ; 32(17): 175702, 2021 Apr 23.
Artículo en Inglés | MEDLINE | ID: mdl-33370722

RESUMEN

Magnetic skyrmions are quasiparticle-like textures that are topologically different from a single domain magnetization state. Their topological protection, combined with the low current density needed to move them, make these objects relevant to be used as information storage structures. In such a context, the analysis of the interactions between skyrmions is interesting and relevant for future applications. In this work, through micromagnetic simulations and numerical calculations, we studied the interaction between two skyrmions living on different parallel ferromagnetic racetracks connected by an exchange-like interaction. The upper and lower racetracks are separated by a height offset and the interaction between the upper and the lower skyrmion is analyzed in terms of the magnetic and geometrical parameters. Three states are predicted, as a function of these parameters: scattered or free skyrmions, bound skymions, and annihilated skyrmions. Our results, presented in a phase diagram, demonstrate that even in the case here called free skyrmions, there is a small and brief interaction when both are close enough, but the skyrmion in the top layer does not drag the skyrmion in the bottom layer. For bound skyrmions, both keep linked during larger times. In the latter case, there are strong changes in the velocity of the skyrmions induced by the effect of a higher effective mass when both are coupled.

4.
Br J Dermatol ; 183(1): 146-154, 2020 07.
Artículo en Inglés | MEDLINE | ID: mdl-31605618

RESUMEN

BACKGROUND: Skin tears are acute wounds that are frequently misdiagnosed and under-reported. A standardized and globally adopted skin tear classification system with supporting evidence for diagnostic validity and reliability is required to allow assessment and reporting in a consistent way. OBJECTIVES: To measure the validity and reliability of the International Skin Tear Advisory Panel (ISTAP) Classification System internationally. METHODS: A multicountry study was set up to validate the content of the ISTAP Classification System through expert consultation in a two-round Delphi procedure involving 17 experts from 11 countries. An online survey including 24 skin tear photographs was conducted in a convenience sample of 1601 healthcare professionals from 44 countries to measure diagnostic accuracy, agreement, inter-rater reliability and intrarater reliability of the instrument. RESULTS: A definition for the concept of a 'skin flap' in the area of skin tears was developed and added to the initial ISTAP Classification System consisting of three skin tear types. The overall agreement with the reference standard was 0·79 [95% confidence interval (CI) 0·79-0·80] and sensitivity ranged from 0·74 (95% CI 0·73-0·75) to 0·88 (95% CI 0·87-0·88). The inter-rater reliability was 0·57 (95% CI 0·57-0·57). The Cohen's Kappa measuring intrarater reliability was 0·74 (95% CI 0·73-0·75). CONCLUSIONS: The ISTAP Classification System is supported by evidence for validity and reliability. The ISTAP Classification System should be used for systematic assessment and reporting of skin tears in clinical practice and research globally. What's already known about this topic? Skin tears are common acute wounds that are misdiagnosed and under-reported too often. A skin tear classification system is needed to standardize documentation and description for clinical practice, audit and research. What does this study add? The International Skin Tear Advisory Panel Classification System was psychometrically tested in 1601 healthcare professionals from 44 countries. Diagnostic accuracy was high when differentiating between type 1, 2 and 3 skin tears using a set of validated photographs.


Asunto(s)
Laceraciones , Traumatismos de los Tejidos Blandos , Humanos , Laceraciones/diagnóstico , Reproducibilidad de los Resultados , Piel/lesiones , Encuestas y Cuestionarios
5.
Microb Cell Fact ; 16(1): 155, 2017 Sep 19.
Artículo en Inglés | MEDLINE | ID: mdl-28927409

RESUMEN

BACKGROUND: Lactobacillus species produce biosurfactants that can contribute to the bacteria's ability to prevent microbial infections associated with urogenital and gastrointestinal tracts and the skin. Here, we described the biological and physicochemical properties of biosurfactants produced by Lactobacillus jensenii P6A and Lactobacillus gasseri P65. RESULTS: The biosurfactants produced by L. jensenii P6A and L. gasseri P65 reduced the water surface tension from 72 to 43.2 mN m-1 and 42.5 mN m-1 as their concentration increased up to the critical micelle concentration (CMC) values of 7.1 and 8.58 mg mL-1, respectively. Maximum emulsifying activity was obtained at concentrations of 1 and 5 mg mL-1 for the P6A and P65 strains, respectively. The Fourier transform infrared spectroscopy data revealed that the biomolecules consist of a mixture of carbohydrates, lipids and proteins. The gas chromatography-mass spectrum analysis of L. jensenii P6A biosurfactant showed a major peak for 14-methypentadecanoic acid, which was the main fatty acid present in the biomolecule; conversely, eicosanoic acid dominated the biosurfactant produced by L. gasseri P65. Although both biosurfactants contain different percentages of the sugars galactose, glucose and ribose; rhamnose was only detected in the biomolecule produced by L. jensenii P6A. Emulsifying activities were stable after a 60-min incubation at 100 °C, at pH 2-10, and after the addition of potassium chloride and sodium bicarbonate, but not in the presence of sodium chloride. The biomolecules showed antimicrobial activity against clinical isolates of Escherichia coli and Candida albicans, with MIC values of 16 µg mL-1, and against Staphylococcus saprophyticus, Enterobacter aerogenes and Klebsiella pneumoniae at 128 µg mL-1. The biosurfactants also disrupted preformed biofilms of microorganisms at varying concentrations, being more efficient against E. aerogenes (64%) (P6A biosurfactant), and E. coli (46.4%) and S. saprophyticus (39%) (P65 biosurfactant). Both strains of lactobacilli could also co-aggregate pathogens. CONCLUSIONS: This report presents the first characterization of biosurfactants produced by L. jensenii P6A and L. gasseri P65. The antimicrobial properties and stability of these biomolecules indicate their potential use as alternative antimicrobial agents in the medical field for applications against pathogens that are responsible for infections in the gastrointestinal and urogenital tracts and the skin.


Asunto(s)
Lactobacillus gasseri/metabolismo , Tensoactivos/química , Tensoactivos/metabolismo , Antiinfecciosos/química , Antiinfecciosos/metabolismo , Antiinfecciosos/farmacología , Bacterias/efectos de los fármacos , Adhesión Bacteriana/efectos de los fármacos , Infecciones Bacterianas/microbiología , Biopelículas/efectos de los fármacos , Candida albicans/efectos de los fármacos , Escherichia coli/efectos de los fármacos , Humanos , Lactobacillus/metabolismo , Espectroscopía Infrarroja por Transformada de Fourier , Tensoactivos/farmacología
6.
Genet Mol Res ; 16(1)2017 Feb 16.
Artículo en Inglés | MEDLINE | ID: mdl-28218783

RESUMEN

In the present study, we demonstrated the in vitro activity of endophytic phosphate-solubilizing bacteria (PSB). Fifty-five endophytic PSB that were isolated from sap, leaves, and roots of maize were tested for their ability to solubilize tricalcium phosphate and produce organic acid. Partial sequencing of the 16S rRNA-encoding gene showed that the isolates were from the genus Bacillus and different species of Enterobacteriaceae. The phosphate solubilization index on solid medium and phosphate solubilization in liquid medium varied significantly among the isolates. There was a statistically significant difference (P ≤ 0.05) for both, the values of phosphate-solubilizing activity and pH of the growth medium, among the isolates. Pearson correlation was statistically significant (P ≤ 0.05) between P-solubilization and pH (R = -0.38), and between the gluconic acid production and the lowering of the pH of the liquid medium at 6 (R = 0.28) and 9 days (R = 0.39). Gluconic acid production was prevalent in all the PSB studied, and Bacillus species were most efficient in solubilizing phosphate. This is the first report on the characterization of bacterial endophytes from maize and their use as potential biofertilizers. In addition, this may provide an alternative strategy for improving the phosphorus acquisition efficiency of crop plants in tropical soils.


Asunto(s)
Bacterias/clasificación , Endófitos/clasificación , Fosfatos/metabolismo , Zea mays/microbiología , Bacterias/genética , Bacterias/aislamiento & purificación , Bacterias/metabolismo , ADN Bacteriano/genética , ADN Ribosómico/genética , Endófitos/genética , Endófitos/aislamiento & purificación , Endófitos/metabolismo , Gluconatos/metabolismo , Filogenia , Hojas de la Planta/microbiología , Raíces de Plantas/microbiología , ARN Ribosómico 16S/genética , Análisis de Secuencia de ADN , Microbiología del Suelo
7.
Br Poult Sci ; 54(6): 780-8, 2013.
Artículo en Inglés | MEDLINE | ID: mdl-24397514

RESUMEN

1. This study evaluated the effects of diets with partial and total substitution of soya bean oil (SO) with flaxseed (linseed) oil (FO) on broiler chicken performance, carcass traits, meat chemical composition and blood serum metabolites. 2. A total of 448 one-d-old Cobb 500 broiler chicken were used. They were allotted among 4 treatments with 8 replications, using a completely randomised design, for 35 d. Four diets were compared: T1 = 100% SO (3%, 1-7 d; 4%, 8-21 d; and 5%, 22-35 d); T2 = 50% SO + 50% FO; T3 = 25% SO + 75% FO and T4 = 100% FO. 3. No significant differences were observed in body weight (BW), body weight gain (BWG), feed intake (FI), feed conversion ratio (FCR) and blood serum metabolites (total triglycerides, TRI; total cholesterol, CHO; high-density lipoprotein, HDL; low-density lipoprotein, LDL; glucose, GLU; albumin, ALB; globulin, GLO; and total proteins, TPs). Significant effects were observed for TRI, CHO, HDL, GLU, HDL, LDL, ALB and GLO with regard to the day of collection. 4. Carcass traits did not show significant differences for the treatments. No significant differences were observed for breast and drumstick chemical compositions, with the exception of drumstick fat concentration (quadratic effect). 5. In conclusion, the partial or total substitution of SO with FO did not affect growth performance, carcass traits, meat chemical composition or blood serum profile in broiler chicken. Therefore, FO can be an alternative to SO in the diet formulation for broiler chicken.


Asunto(s)
Pollos/fisiología , Aceite de Linaza/farmacología , Carne/análisis , Aumento de Peso/efectos de los fármacos , Alimentación Animal/análisis , Animales , Análisis Químico de la Sangre/veterinaria , Pollos/crecimiento & desarrollo , Dieta/veterinaria , Relación Dosis-Respuesta a Droga , Aceite de Linaza/administración & dosificación
8.
J Phys Condens Matter ; 33(26)2021 May 28.
Artículo en Inglés | MEDLINE | ID: mdl-33902016

RESUMEN

When the skyrmion dynamics beyond the particle-like description is considered, this topological structure can deform due to a self-induced field. In this work, we perform Monte Carlo simulations to characterize the skyrmion deformation during its steady movement. In the low-velocity regime, the deformation in the skyrmion shape is quantified by an effective inertial mass, which is related to the dissipative force. When skyrmions move faster, the large self-induced deformation triggers topological transitions. These transitions are characterized by the proliferation of skyrmions and a different total topological charge, which is obtained as a function of the skyrmion velocity. Our findings provide an alternative way to describe the dynamics of a skyrmion that accounts for the deformations of its structure. Furthermore, such motion-induced topological phase transitions make it possible to control the number of ferromagnetic skyrmions through velocity effects.

9.
Microsc Res Tech ; 80(8): 831-837, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28370895

RESUMEN

Piper solmsianum C.DC., which is popularly known as pariparoba, is a shrub that measures 1-3 m in height and it inhabits areas with wet tropical soils. The objective of this study was to analyze the leaf and stem anatomy using light microscopy, scanning electron micrographs, and energy-dispersive X-ray spectroscopy in order to provide information for species identification. The anatomical profile showed the following main microscopic markers: hypostomatic leaf; hypodermis layer on both sides; pearl glands; biconvex midrib shape; five collateral vascular bundles in open arc with the central bundle larger than the others; circular stem shape; collateral vascular bundles arranged in two rings; sinuous sclerenchymatic sheath in the pith; secretory idioblasts; and starch grains in the mesophyll, in the ground parenchyma of the midrib, petiole, and in the stem; and six morphotypes of calcium oxalate crystals (styloids, cuneiform, tabular crystal rosettes, cuneiform crystal rosettes, elongated square dipyramids, as well as very elongated square dipyramids).


Asunto(s)
Piper/ultraestructura , Hojas de la Planta/ultraestructura , Tallos de la Planta/ultraestructura , Microscopía Electrónica de Rastreo , Piper/química , Hojas de la Planta/química , Tallos de la Planta/química , Espectrometría por Rayos X
10.
Braz J Biol ; 76(4): 871-877, 2016.
Artículo en Inglés | MEDLINE | ID: mdl-27143069

RESUMEN

Concentrations of ten elements (Cd, Cr, Cu, Fe, Ni, Pb, Se, Sr, V and Zn) were determinate in muscle tissues of 13 fish species from Aratu Bay, Bahia, Brazil by inductively coupled plasma optical emission spectrometry. The accuracy and precision of our results were checked by using two certified reference materials: BCR-422 cod muscle and SRM 1566b oyster tissue. The average trace element concentrations in the fish species varied in the following ranges, in µg g-1: 0.03-0.8 for Cr; 2.0-33.7 for Cu, 2.4-135.1 for Fe, 1.6-25.6 for Se; 1.6-35.1 for Sr; and 2.8-40.5 for Zn. The Diaptereus rhombeus (carapeba) specie presented the highest concentrations of Se, Cu and Fe. Chromium and Se were present at levels above the limit of tolerance allowed by the National Agency of Sanitary Vigilance (ANVISA). The results were also evaluated using the multivariate analysis techniques: principal component analysis (PCA) and hierarchical cluster analysis (HCA).


Asunto(s)
Peces , Alimentos Marinos/análisis , Oligoelementos/análisis , Animales , Bahías , Brasil , Análisis por Conglomerados , Contaminación de Alimentos , Metales/análisis , Músculos/química , Análisis de Componente Principal
11.
Braz J Biol ; 76(1): 194-204, 2016 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-26909636

RESUMEN

In this study, concentrations of trace elements in tissues of shrimp species (Litopenaeus vannamei) from farming and zone natural coastal located in the northeastern Brazil were investigated. The elements determination was performed by optical emission spectrometry with inductively coupled plasma (ICP OES). The following ranges of concentrations in the tissues were obtained in µg g-1 dry weight: Al: 13.4-886.5, Cd: 0.93-1.80; Cu: 24.8-152; Fe: 3.2-410.9; Mn: 0.36-24.4; Se: 0.094-9.81 and Zn: 20.3-109.4. The shrimp muscle can be a good iron source (about 88.9 mg-1g dry weight). The distribution of Se concentration in tissues showed much variation between locations, and the concentration levels found in shrimp muscles of wild samples were high, where its levels in 67% of muscle and 50% of others tissues samples exceeded the ANVISA limit, indicating evidence of selenium bioaccumulation. Significant correlation was observed between the following pairs of elements: Fe-Zn (r= -0.70), Mn-Cu (r= -0.74), Se-Cu (r= -0.68), Se-Mn (r= 0.82) in the muscles; Fe-Al (r= 0.99), Mn-Al (r= 0.62), Mn-Fe (r= 0.62), Se-Al (r = 0.88), Se-Fe (r= 0.87), Se-Mn (r= 0.58) in the exoskeleton and Cu-Zn (r = 0.68), Al-Cu (r= 0.88), Fe-Cu (r= 0.95) and Fe-Al (r= 0.97) in the viscera.


Asunto(s)
Penaeidae/fisiología , Oligoelementos/metabolismo , Animales , Acuicultura , Brasil , Espectrofotometría Atómica , Distribución Tisular
12.
Arq. bras. med. vet. zootec. (Online) ; 73(5): 1187-1193, Sept.-Oct. 2021. tab
Artículo en Inglés | LILACS, VETINDEX | ID: biblio-1345279

RESUMEN

This research article aims to evaluate the effect of total replacement of corn by soybean meal and urea on intake and apparent digestibility of dry matter and its components, production and composition of milk and feeding behavior of lactating cows grazing, with intermittent stocking Mombaça grass (Megathyrsus maximus cv. Mombaça). Twelve milking cows were distributed in a triple 4 x 4 latin square. Experimental treatments consisted of four soybean meal replacement levels by corn more urea (0; 33; 66; 100%). The grass has an average content of crude protein and neutral detergent fiber of 19% and 59%, respectively. The replacement of soybean meal by corn and urea did not affect the intake and digestibility of nutrients. A linear reduction of milk production was observed, but there was no change in milk production corrected to 4.0% of fat. The milk components (g/kg) of fat, protein, lactose, and total solids were not altered, as well as feeding behavior. Under the conditions of this study, the replacement of the diets is suitable for crossbred dairy cows in lactation third medium, producing in average of 12.5 kg/day-1 when kept in quality pastures.(AU)


Este artigo de pesquisa tem como objetivo avaliar o efeito da substituição total do milho pelo farelo de soja e ureia sobre o consumo e a digestibilidade aparente da matéria seca e de seus componentes, a produção e a composição do leite e o comportamento alimentar de vacas em lactação mantidas em pastos capim-mombaça (Megathyrsus maximus cv. Mombaça) manejado sob lotação intermitente. Doze vacas em lactação foram distribuídas em um quadrado latino triplo 4 x 4. Os tratamentos experimentais consistiram de quatro níveis de substituição do farelo de soja pelo milho mais ureia (0; 33; 66; 100%). O capim-mombaça apresentou um teor médio de proteína bruta e de fibra em detergente neutro de 19% e 59%, respectivamente. A substituição do farelo de soja por milho e ureia não afetou o consumo e a digestibilidade dos nutrientes. Observou-se redução linear da produção de leite, mas não houve alteração na produção de leite corrigida para 4,0% de gordura. Os componentes do leite (g/kg): gordura, proteína, lactose e sólidos totais não foram alterados, assim como o comportamento ingestivo dos animais. Nas condições deste estudo, a substituição total do milho pelo farelo de soja e ureia nas dietas é adequada para vacas mestiças leiteiras em terço médio de lactação, produzindo, em média, 12,5 kg / dia-1 quando mantidas em pastagens de qualidade.(AU)


Asunto(s)
Animales , Femenino , Bovinos , Glycine max , Urea , Zea mays , Dieta/veterinaria , Alimentación Animal , Proteínas de la Leche/análisis
13.
Arq. bras. med. vet. zootec. (Online) ; 72(4): 1449-1457, July-Aug. 2020. tab
Artículo en Inglés | LILACS, VETINDEX | ID: biblio-1131489

RESUMEN

This study aimed to assess different prebiotic concentrations and principles, in addition to calcium butyrate, aiming to replace colistin as a growth promoter. The sample consisted of 120 piglets weaned at 22 days old with mean initial weight of 5.475 ± 0.719kg. The animals were assigned to random blocks in six treatments corresponding to the use of the following dietary additives: T1) colistin (40 ppm); T2) ß-glucan/mannan-oligosaccharides (0.2%); T3) calcium butyrate (0.1%); T4) ß-glucan/mannan-oligosaccharides (0.1%) + fructooligosaccharides (0.01%) + galactooligosaccharides (0.09%); T5) ß-glucan/mannan-oligosaccharides (0.1%) + fructooligosaccharides (0.03%) + galactooligosaccharides (0.07%); and T6) ß-glucan/mannan-oligosaccharides (0.1%) + fructooligosaccharides (0.05%) + galactooligosaccharides (0.05%). The results showed no difference among treatments for the performance parameters in any of the phases evaluated. For diarrhea incidence and intensity, the results indicated that the treatments with alternative additives had similar effects as the group treated with colistin. A significant difference was found for the profile of propionic acid (0.23% colistin and 0.32%, 0.36%, 0.37% additives) and total fatty acids (0.67% colistin and 0.97% additives) values in the caecum. The supplementation with different compositions and concentrations of prebiotics and butyric acid may viably replace colistin in controlling diarrhea and modulating volatile fatty acid production in the caecum.(AU)


O objetivo deste trabalho foi avaliar as diferentes concentrações e princípios de prebióticos e do butirato de sódio, visando substituir a colistina como promotor de crescimento. Foram utilizados 120 leitões, desmamados aos 22 dias de idade, com peso médio inicial de 5,475 ± 0,719kg. Os animais foram distribuídos em blocos ao acaso, em seis tratamentos, que corresponderam ao uso dos seguintes aditivos dietéticos: T1) colistina (40ppm); T2) ß-glucanos/mananoligossacarídeos (0,2%); T3) butirato de cálcio (0,1%); T4) ß-glucanos/mananoligossacarídeos (0,1%) + frutoligossacarídeos (0,01%) + galactoligossacarídeos (0,09%); T5) ß-glucanos/mananoligossacarídeos (0,1%) + frutoligossacarídeos (0,03%) + galactoligossacarídeos (0,07%); e T6) ß-glucanos/mananoligossacarídeos (0,1%) + frutoligossacarídeos (0,05%) + galactoligossacarídeos (0,05%). Os resultados mostraram que não houve diferença entre os tratamentos para nenhum dos parâmetros de desempenho em nenhuma das fases avaliadas. Para a incidência e a intensidade de diarreia, os resultados apontam que os tratamentos com os aditivos alternativos apresentaram efeitos semelhantes aos do grupo tratado com colistina. Foi encontrada diferença significativa para perfil dos ácidos graxos propiônicos (0,23% colistina e 0,32%, 0,36%, 0,37% aditivos) e ácidos totais (0,67% colistina e 0,97% aditivos) no ceco. A suplementação com diferentes composições e concentrações de prebióticos e do ácido butírico pode substituir a colistina de forma viável no controle da diarreia e na modulação da produção volátil de ácidos graxos no ceco.(AU)


Asunto(s)
Animales , Porcinos/crecimiento & desarrollo , Ácido Butírico/administración & dosificación , Prebióticos/administración & dosificación , Aumento de Peso , Aditivos Alimentarios/administración & dosificación
14.
Toxicon ; 37(4): 587-607, 1999 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-10082160

RESUMEN

Loxosceles spp. (brown spider) envenomation has been reported to provoke dermonecrosis and haemorrhage at the bite site (a hallmark of accidents) and, to a lesser extent, thrombocytopenia, hemolysis and disseminated intravascular coagulation in some cases. Using lectin-immunolabeling, lectin-affinity chromatography, glycosidase and proteinase K treatments we were able to identify several venom N-glycosylated proteins with high-mannose oligosaccharide structures, complex-type glycoconjugates such as fucosylated glycans, but no galactose or sialic acid residues as complex sugars or glycosaminoglycan residues. Working with enzymatically or chemically deglycosylated venom we found that platelet aggregation (thrombocytopenic activity) as well as the fibronectinolytic and fibrinogenolytic (haemorrhagic) effects of the venom were sugar-independent when compared to glycosylated venom. Nevertheless, zymograph analysis in co-polymerized gelatin gels showed that enzymatic N-deglycosylation of loxolysin-B, a high-mannose 32-35 kDa glycoprotein of the venom with gelatinolytic metalloproteinase activity, caused a reduction of approximately 2 kDa in its molecular weight and a reduction of the gelatinolytic effect to a residual activity of 28% when compared to the glycosylated molecule, indicating a post-translational glycosylation-dependent gelatinolytic effect. Analysis of the dermonecrotic effect of the chemically or enzymatically N-deglycosylated venom detected only residual activity when compared with the glycosylated control. Thus, the present report suggests that oligosaccharide moieties play a role in the destructive effects of brown spider venom and opens the possibility for a carbohydrate-based therapy.


Asunto(s)
Oligosacáridos/química , Enfermedades de la Piel/inducido químicamente , Venenos de Araña/química , Animales , Carbohidratos/farmacología , Cromatografía de Afinidad , Electroforesis , Fibrinógeno/efectos de los fármacos , Fibronectinas/efectos de los fármacos , Glicosilación , Humanos , Immunoblotting , Necrosis , Agregación Plaquetaria , Conejos , Enfermedades de la Piel/etiología , Venenos de Araña/metabolismo , Arañas
15.
Ostomy Wound Manage ; 47(12): 43-51, 2001 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-11889727

RESUMEN

Urinary incontinence is a social and hygienic problem that affects 15% to 35% of individuals aged 60 years or older, with an estimated annual cost in the United States of $16 billion. To better understand the effects of misinformation and underestimation of the problem, a study to identify knowledge and attitudes related to urinary incontinence was conducted among 400 community-dwelling residents (55 years of age or older). The instrument covered four knowledge/attitude subject areas: treatment and effects, causes, the relationship between aging and urinary incontinence, and physician/patient discussion regarding urinary incontinence. Interviews were conducted in waiting rooms, shopping centers, subways, and hospital/clinic waiting rooms. One hundred, forty-two people (43% women and 23% men) reported current or previous bladder problems. Only two of the 14 knowledge statements elicited a correct response from the majority (60%) of participants. The percentage of correct answers to the other 12 statements ranged from 23% to 43%. Most people believed that urinary incontinence is an inevitable consequence of aging, and the majority of treatment responses (58%) indicated a lack of knowledge about available treatments. Differences in the percentage of correct responses related to the treatment and causes of urinary incontinence were observed between respondents with varying educational levels (P = 0.001) and between Caucasian and African American respondents (P = 0.001). The results confirm that misinformation about urinary incontinence is common in the general population and that educational interventions are needed if the prevalence of uncontrolled urinary incontinence is to be solved.


Asunto(s)
Actitud Frente a la Salud/etnología , Conocimientos, Actitudes y Práctica en Salud , Incontinencia Urinaria/etnología , Distribución por Edad , Factores de Edad , Anciano , Anciano de 80 o más Años , Brasil/epidemiología , Escolaridad , Femenino , Humanos , Masculino , Persona de Mediana Edad , Evaluación de Necesidades , Prejuicio , Encuestas y Cuestionarios , Población Urbana , Incontinencia Urinaria/diagnóstico , Incontinencia Urinaria/etiología , Incontinencia Urinaria/terapia
16.
Ostomy Wound Manage ; 45(4): 46-50, 52-4, 56 passim, 1999 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-10347510

RESUMEN

The aim of this study is to identify the self-perceptions of patients at different postoperative phases and settings. The case study involves two ostomy patients: a young woman with a temporary ileostomy, and an older man with a permanent colostomy. Both patients were interviewed while still in the hospital on the third, fifth, and seventh postoperative days, and on the second day of the first and third months after discharge. Four major factors were identified after the patients were analyzed: social support, health and life expectations, physical suffering, and self-care. Family support predominated the social support category for both patients. The results showed that the patients' perceptions about having an ostomy were not influenced by the type of ostomy (i.e., whether the ostomy was temporary or permanent in the in-hospital phase). However, these results/perceptions, primarily those related to health and life expectancy and self-care, changed early in the study. We believe it is important for the healthcare team to know the perceptions patients have about their ostomies and themselves postoperatively. This, in turn, may contribute to systematic and personalized care based on specific patients' demands that vary at different stages of treatment and, most certainly, in different cultures.


Asunto(s)
Colostomía/psicología , Ileostomía/psicología , Cuidados Posoperatorios/psicología , Autoimagen , Adulto , Actitud Frente a la Salud , Colostomía/enfermería , Femenino , Humanos , Ileostomía/enfermería , Masculino , Persona de Mediana Edad , Evaluación en Enfermería , Alta del Paciente , Cuidados Posoperatorios/métodos , Cuidados Posoperatorios/enfermería , Autocuidado , Apoyo Social
17.
J Clin Pediatr Dent ; 17(4): 221-5, 1993.
Artículo en Inglés | MEDLINE | ID: mdl-8217886

RESUMEN

The aim of this study was to evaluate clinically a bonded space maintainer, which would reduce chair-side time and cost. Sixty appliances were fabricated from 0.7 mm stainless steel round wire and bonded using light-cured composite to the two teeth adjacent to the site of extraction of a posterior primary tooth. Twenty males and sixteen females (age range 5-9-years-old) were selected from the Pedodontic clinic of the State University of Rio de Janeiro. The sixty space maintainers were divided into two groups according to the site in which they were placed: a) absent first primary molar and b) absent second primary molar. Impressions and study models were obtained prior to and 6 months after bonding the appliances. During this period only 8.3% of failures were observed, most of them from occlusal or facial trauma. Student t-test did not show statistically significant alterations in the sizes of the maintained spaces during the trial period.


Asunto(s)
Recubrimiento Dental Adhesivo , Mantenimiento del Espacio en Ortodoncia/instrumentación , Niño , Preescolar , Estudios de Evaluación como Asunto , Femenino , Humanos , Masculino , Diente Molar/cirugía , Extracción Dental/efectos adversos , Migración del Diente/etiología , Migración del Diente/prevención & control , Diente Primario
18.
Rev Lat Am Enfermagem ; 6(3): 43-54, 1998 Jul.
Artículo en Portugués | MEDLINE | ID: mdl-9752254

RESUMEN

The authors show the trajectory of the Brazilian Stomal Therapy Courses since their beginning in 1990 until 1995. Firstly they point out the changes of their contents initially based on medical and biological fields. Nowadays they also involve issues in the other Enterostomal Therapy fields-wounds and incontinence-besides discussions and reflections on the principles of organization and creation of care programmes, services and protocols as well as on the Stomal Therapy as a specialty in Brazilian nursing, society and politics. The 75 students' expectations, perspectives and evaluation related to the courses are presented, showing positive tendencies. The author finishes the study considering the importance of the evaluation process towards the improvement of the course according to the new challenges and discussions about nursing specialties in our country.


Asunto(s)
Educación Continua en Enfermería/organización & administración , Incontinencia Fecal/enfermería , Estomía/enfermería , Especialidades de Enfermería/educación , Incontinencia Urinaria/enfermería , Heridas y Lesiones/enfermería , Adulto , Brasil , Curriculum , Femenino , Humanos , Masculino , Persona de Mediana Edad , Investigación en Educación de Enfermería , Evaluación de Programas y Proyectos de Salud , Estudiantes de Enfermería/psicología
19.
Rev Lat Am Enfermagem ; 8(3): 40-50, 2000 Jul.
Artículo en Portugués | MEDLINE | ID: mdl-11111688

RESUMEN

This study aimed at analyzing nurses (re)construction process regarding the meanings of ostomy, ostomized patients, nursing care and the professional role after they wore an ostomy appliance. This activity is a teaching strategy applied at the Enterostomal Therapy Nursing Education Program. Two major units were identified after the analysis of students speeches: "being an ostomized person" and "being a professional". When students wore the pouches they felt as ostomized patients experiencing a violation of their identity and quality of life that promotes profound changes in daily life. These symbolic contents cause a crisis regarding the meaning of being a professional as until this experience, nursing care seemed fragmented to them. Recognizing a previous care performed as a technical action mainly directed to the ostomy and the pouch, students were able to visualize a future care, that is holistic and considers the ostomized human being, enabling them to incorporate affective, symbolic and relational dimensions.


Asunto(s)
Educación en Enfermería/métodos , Estomía/psicología , Desempeño de Papel , Autoimagen , Estudiantes de Enfermería/psicología , Enseñanza/métodos , Actividades Cotidianas , Actitud del Personal de Salud , Humanos , Calidad de Vida
20.
Rev Esc Enferm USP ; 27(1): 87-93, 1993 Apr.
Artículo en Portugués | MEDLINE | ID: mdl-8165342

RESUMEN

The author approaches about historical aspects, concepts, etiology and treatment of digestive fistula. The skin care and drainage control are the basis of stomal therapy. So, the author discusses the specific nursing and ET care in this subject, including evaluation, procedures and resources.


Asunto(s)
Enfermedades del Sistema Digestivo/enfermería , Fístula/enfermería , Estomía/enfermería , Cuidados de la Piel/enfermería , Humanos , Cuidados de la Piel/métodos
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