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1.
Combined oral 5-azacytidine and romidepsin are highly effective in patients with PTCL: a multicenter phase 2 study.
Blood
; 137(16): 2161-2170, 2021 04 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-33171487
2.
Oral 5-azacytidine and romidepsin exhibit marked activity in patients with PTCL: a multicenter phase 1 study.
Blood
; 134(17): 1395-1405, 2019 10 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31471376
3.
Characterization of newly established Pralatrexate-resistant cell lines and the mechanisms of resistance.
BMC Cancer
; 21(1): 879, 2021 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-34332580
4.
IL-22-Independent Protection from Colitis in the Absence of Nkx2.3 Transcription Factor in Mice.
J Immunol
; 202(6): 1833-1844, 2019 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30700585
5.
Generation of pralatrexate resistant T-cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers.
Genes Chromosomes Cancer
; 59(11): 639-651, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32614991
6.
Silencing c-Myc translation as a therapeutic strategy through targeting PI3Kδ and CK1ε in hematological malignancies.
Blood
; 129(1): 88-99, 2017 01 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27784673
7.
Epigenetic inactivation of TRAIL decoy receptors at 8p12-21.3 commonly deleted region confers sensitivity to Apo2L/trail-Cisplatin combination therapy in cervical cancer.
Genes Chromosomes Cancer
; 55(2): 177-89, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26542757
8.
The combination of hypomethylating agents and histone deacetylase inhibitors produce marked synergy in preclinical models of T-cell lymphoma.
Br J Haematol
; 171(2): 215-226, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26194163
9.
Sirtuin and pan-class I/II deacetylase (DAC) inhibition is synergistic in preclinical models and clinical studies of lymphoma.
Blood
; 122(12): 2104-13, 2013 Sep 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-23913470
10.
Cancer testis antigen expression across T-cell lymphoma subtypes.
Hematol Oncol
; 38(5): 827-830, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32744349
11.
PCDH10 promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis.
Genes Chromosomes Cancer
; 52(11): 1030-41, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23929756
12.
HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL.
Blood
; 118(20): 5506-16, 2011 Nov 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-21772049
13.
Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms.
Cancers (Basel)
; 15(20)2023 Oct 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37894327
14.
Targeting the T-Cell Lymphoma Epigenome Induces Cell Death, Cancer Testes Antigens, Immune-Modulatory Signaling Pathways.
Mol Cancer Ther
; 20(8): 1422-1430, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34108263
15.
R-Loop-Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin.
Mol Cancer Res
; 19(8): 1361-1374, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34050002
16.
The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies.
Blood
; 112(7): 2906-16, 2008 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18591385
17.
Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer.
Genes Chromosomes Cancer
; 48(11): 983-92, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19681120
18.
ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest.
Oncotarget
; 11(37): 3432-3442, 2020 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32973968
19.
The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma.
Oncotarget
; 11(18): 1576-1589, 2020 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32405334
20.
N-quinoline-benzenesulfonamide derivatives exert potent anti-lymphoma effect by targeting NF-κB.
iScience
; 23(12): 101884, 2020 Dec 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33354662