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1.

Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity.

Kalafati, Lydia; Kourtzelis, Ioannis; Schulte-Schrepping, Jonas; Li, Xiaofei; Hatzioannou, Aikaterini; Grinenko, Tatyana; Hagag, Eman; Sinha, Anupam; Has, Canan; Dietz, Sevina; de Jesus Domingues, Antonio Miguel; Nati, Marina; Sormendi, Sundary; Neuwirth, Ales; Chatzigeorgiou, Antonios; Ziogas, Athanasios; Lesche, Mathias; Dahl, Andreas; Henry, Ian; Subramanian, Pallavi; Wielockx, Ben; Murray, Peter; Mirtschink, Peter; Chung, Kyoung-Jin; Schultze, Joachim L; Netea, Mihai G; Hajishengallis, George; Verginis, Panayotis; Mitroulis, Ioannis; Chavakis, Triantafyllos.

Cell ; 183(3): 771-785.e12, 2020 10 29.

Artículo en Inglés | MEDLINE | ID: mdl-33125892

2.

CD38 promotes hematopoietic stem cell dormancy.

Ibneeva, Liliia; Singh, Sumeet Pal; Sinha, Anupam; Eski, Sema Elif; Wehner, Rebekka; Rupp, Luise; Kovtun, Iryna; Pérez-Valencia, Juan Alberto; Gerbaulet, Alexander; Reinhardt, Susanne; Wobus, Manja; von Bonin, Malte; Sancho, Jaime; Lund, Frances; Dahl, Andreas; Schmitz, Marc; Bornhäuser, Martin; Chavakis, Triantafyllos; Wielockx, Ben; Grinenko, Tatyana.

PLoS Biol ; 22(2): e3002517, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38422172

3.

Epigenomic Profiling of Human CD4⁺ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development.

Durek, Pawel; Nordström, Karl; Gasparoni, Gilles; Salhab, Abdulrahman; Kressler, Christopher; de Almeida, Melanie; Bassler, Kevin; Ulas, Thomas; Schmidt, Florian; Xiong, Jieyi; Glazar, Petar; Klironomos, Filippos; Sinha, Anupam; Kinkley, Sarah; Yang, Xinyi; Arrigoni, Laura; Amirabad, Azim Dehghani; Ardakani, Fatemeh Behjati; Feuerbach, Lars; Gorka, Oliver; Ebert, Peter; Müller, Fabian; Li, Na; Frischbutter, Stefan; Schlickeiser, Stephan; Cendon, Carla; Fröhler, Sebastian; Felder, Bärbel; Gasparoni, Nina; Imbusch, Charles D; Hutter, Barbara; Zipprich, Gideon; Tauchmann, Yvonne; Reinke, Simon; Wassilew, Georgi; Hoffmann, Ute; Richter, Andreas S; Sieverling, Lina; Chang, Hyun-Dong; Syrbe, Uta; Kalus, Ulrich; Eils, Jürgen; Brors, Benedikt; Manke, Thomas; Ruland, Jürgen; Lengauer, Thomas; Rajewsky, Nikolaus; Chen, Wei; Dong, Jun; Sawitzki, Birgit.

Immunity ; 45(5): 1148-1161, 2016 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-27851915

4.

The RNA binding protein human antigen R is a gatekeeper of liver homeostasis.

Subramanian, Pallavi; Gargani, Sofia; Palladini, Alessandra; Chatzimike, Margarita; Grzybek, Michal; Peitzsch, Mirko; Papanastasiou, Anastasios D; Pyrina, Iryna; Ntafis, Vasileios; Gercken, Bettina; Lesche, Mathias; Petzold, Andreas; Sinha, Anupam; Nati, Marina; Thangapandi, Veera Raghavan; Kourtzelis, Ioannis; Andreadou, Margarita; Witt, Anke; Dahl, Andreas; Burkhardt, Ralph; Haase, Robert; Domingues, António Miguel de Jesus; Henry, Ian; Zamboni, Nicola; Mirtschink, Peter; Chung, Kyoung-Jin; Hampe, Jochen; Coskun, Ünal; Kontoyiannis, Dimitris L; Chavakis, Triantafyllos.

Hepatology ; 75(4): 881-897, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-34519101

5.

HIF2α is a direct regulator of neutrophil motility.

Sormendi, Sundary; Deygas, Mathieu; Sinha, Anupam; Bernard, Mathilde; Krüger, Anja; Kourtzelis, Ioannis; Le Lay, Gregoire; Sáez, Pablo J; Gerlach, Michael; Franke, Kristin; Meneses, Ana; Kräter, Martin; Palladini, Alessandra; Guck, Jochen; Coskun, Ünal; Chavakis, Triantafyllos; Vargas, Pablo; Wielockx, Ben.

Blood ; 137(24): 3416-3427, 2021 06 17.

Artículo en Inglés | MEDLINE | ID: mdl-33619535

6.

HIF1α is a direct regulator of steroidogenesis in the adrenal gland.

Watts, Deepika; Stein, Johanna; Meneses, Ana; Bechmann, Nicole; Neuwirth, Ales; Kaden, Denise; Krüger, Anja; Sinha, Anupam; Alexaki, Vasileia Ismini; Kircher, Stefan; Martinez, Antoine; Theodoropoulou, Marily; Eisenhofer, Graeme; Peitzsch, Mirko; El-Armouche, Ali; Chavakis, Triantafyllos; Wielockx, Ben.

Cell Mol Life Sci ; 78(7): 3577-3590, 2021 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-33464382

7.

Hematopoietic stem cell response to acute thrombocytopenia requires signaling through distinct receptor tyrosine kinases.

Ramasz, Beáta; Krüger, Anja; Reinhardt, Julia; Sinha, Anupam; Gerlach, Michael; Gerbaulet, Alexander; Reinhardt, Susanne; Dahl, Andreas; Chavakis, Triantafyllos; Wielockx, Ben; Grinenko, Tatyana.

Blood ; 134(13): 1046-1058, 2019 09 26.

Artículo en Inglés | MEDLINE | ID: mdl-31434705

8.

Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice.

Aden, Konrad; Bartsch, Kareen; Dahl, Joseph; Reijns, Martin A M; Esser, Daniela; Sheibani-Tezerji, Raheleh; Sinha, Anupam; Wottawa, Felix; Ito, Go; Mishra, Neha; Knittler, Katharina; Burkholder, Adam; Welz, Lina; van Es, Johan; Tran, Florian; Lipinski, Simone; Kakavand, Nassim; Boeger, Christine; Lucius, Ralph; von Schoenfels, Witigo; Schafmayer, Clemens; Lenk, Lennart; Chalaris, Athena; Clevers, Hans; Röcken, Christoph; Kaleta, Christoph; Rose-John, Stefan; Schreiber, Stefan; Kunkel, Thomas; Rabe, Björn; Rosenstiel, Philip.

Gastroenterology ; 156(1): 145-159.e19, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-30273559

9.

Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease.

Zeissig, Sebastian; Rosati, Elisa; Dowds, C Marie; Aden, Konrad; Bethge, Johannes; Schulte, Berenice; Pan, Wei Hung; Mishra, Neha; Zuhayra, Maaz; Marx, Marlies; Paulsen, Maren; Strigli, Anne; Conrad, Claudio; Schuldt, Dörthe; Sinha, Anupam; Ebsen, Henriette; Kornell, Sabin-Christin; Nikolaus, Susanna; Arlt, Alexander; Kabelitz, Dieter; Ellrichmann, Mark; Lützen, Ulf; Rosenstiel, Philip C; Franke, Andre; Schreiber, Stefan.

Gut ; 68(1): 25-39, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-29730603

10.

DNA Methylation and Transcription Patterns in Intestinal Epithelial Cells From Pediatric Patients With Inflammatory Bowel Diseases Differentiate Disease Subtypes and Associate With Outcome.

Howell, Kate Joanne; Kraiczy, Judith; Nayak, Komal M; Gasparetto, Marco; Ross, Alexander; Lee, Claire; Mak, Tim N; Koo, Bon-Kyoung; Kumar, Nitin; Lawley, Trevor; Sinha, Anupam; Rosenstiel, Philip; Heuschkel, Robert; Stegle, Oliver; Zilbauer, Matthias.

Gastroenterology ; 154(3): 585-598, 2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-29031501

11.

Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.

Schmidt, Florian; Gasparoni, Nina; Gasparoni, Gilles; Gianmoena, Kathrin; Cadenas, Cristina; Polansky, Julia K; Ebert, Peter; Nordström, Karl; Barann, Matthias; Sinha, Anupam; Fröhler, Sebastian; Xiong, Jieyi; Dehghani Amirabad, Azim; Behjati Ardakani, Fatemeh; Hutter, Barbara; Zipprich, Gideon; Felder, Bärbel; Eils, Jürgen; Brors, Benedikt; Chen, Wei; Hengstler, Jan G; Hamann, Alf; Lengauer, Thomas; Rosenstiel, Philip; Walter, Jörn; Schulz, Marcel H.

Nucleic Acids Res ; 45(1): 54-66, 2017 01 09.

Artículo en Inglés | MEDLINE | ID: mdl-27899623

12.

Strategies for Expanding Iohexol Supply During a Shortage.

Sinha, Anupam; Conliffe, Theodore.

Radiology ; 307(1): e221515, 2023 04.

Artículo en Inglés | MEDLINE | ID: mdl-36413133

13.

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease.

Häsler, Robert; Sheibani-Tezerji, Raheleh; Sinha, Anupam; Barann, Matthias; Rehman, Ateequr; Esser, Daniela; Aden, Konrad; Knecht, Carolin; Brandt, Berenice; Nikolaus, Susanna; Schäuble, Sascha; Kaleta, Christoph; Franke, Andre; Fretter, Christoph; Müller, Werner; Hütt, Marc-Thorsten; Krawczak, Michael; Schreiber, Stefan; Rosenstiel, Philip.

Gut ; 66(12): 2087-2097, 2017 12.

Artículo en Inglés | MEDLINE | ID: mdl-27694142

14.

Hip Injuries Following Steroid Injection.

Sinha, Anupam; Mehnert, Michael.

Radiology ; 294(2): 482-483, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31891325

15.

Novel mutations of the arylsulphatase B (ARSB) gene in Indian patients with mucopolysaccharidosis type VI.

Uttarilli, Anusha; Ranganath, Prajnya; Jain, S Jamal Md Nurul; Prasad, C Krishna; Sinha, Anupam; Verma, Ishwar C; Phadke, Shubha R; Puri, Ratna D; Danda, Sumita; Muranjan, Mamta N; Jevalikar, Ganesh; Nagarajaram, H A; Dalal, Ashwin B.

Indian J Med Res ; 142(4): 414-25, 2015 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-26609033

16.

Nodes occupying central positions in human tissue specific PPI networks are enriched with many splice variants.

Sinha, Anupam; Nagarajaram, Hampapathalu Adimurthy.

Proteomics ; 14(20): 2242-8, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-25092398

17.

Effect of alternative splicing on the degree centrality of nodes in protein-protein interaction networks of Homo sapiens.

Sinha, Anupam; Nagarajaram, Hampapathalu Adimurthy.

J Proteome Res ; 12(4): 1980-8, 2013 Apr 05.

Artículo en Inglés | MEDLINE | ID: mdl-23406498

18.

Succinate mediates inflammation-induced adrenocortical dysfunction.

Mateska, Ivona; Witt, Anke; Hagag, Eman; Sinha, Anupam; Yilmaz, Canelif; Thanou, Evangelia; Sun, Na; Kolliniati, Ourania; Patschin, Maria; Abdelmegeed, Heba; Henneicke, Holger; Kanczkowski, Waldemar; Wielockx, Ben; Tsatsanis, Christos; Dahl, Andreas; Walch, Axel Karl; Li, Ka Wan; Peitzsch, Mirko; Chavakis, Triantafyllos; Alexaki, Vasileia Ismini.

Elife ; 122023 07 14.

Artículo en Inglés | MEDLINE | ID: mdl-37449973

19.

Fatty acid desaturase 2 determines the lipidomic landscape and steroidogenic function of the adrenal gland.

Witt, Anke; Mateska, Ivona; Palladini, Alessandra; Sinha, Anupam; Wölk, Michele; Harauma, Akiko; Bechmann, Nicole; Pamporaki, Christina; Dahl, Andreas; Rothe, Michael; Kopaliani, Irakli; Adolf, Christian; Riester, Anna; Wielockx, Ben; Bornstein, Stefan R; Kroiss, Matthias; Peitzsch, Mirko; Moriguchi, Toru; Fedorova, Maria; Grzybek, Michal; Chavakis, Triantafyllos; Mirtschink, Peter; Alexaki, Vasileia Ismini.

Sci Adv ; 9(29): eadf6710, 2023 07 21.

Artículo en Inglés | MEDLINE | ID: mdl-37478183

20.

Alterations in the hepatocyte epigenetic landscape in steatosis.

Maji, Ranjan Kumar; Czepukojc, Beate; Scherer, Michael; Tierling, Sascha; Cadenas, Cristina; Gianmoena, Kathrin; Gasparoni, Nina; Nordström, Karl; Gasparoni, Gilles; Laggai, Stephan; Yang, Xinyi; Sinha, Anupam; Ebert, Peter; Falk-Paulsen, Maren; Kinkley, Sarah; Hoppstädter, Jessica; Chung, Ho-Ryun; Rosenstiel, Philip; Hengstler, Jan G; Walter, Jörn; Schulz, Marcel H; Kessler, Sonja M; Kiemer, Alexandra K.

Epigenetics Chromatin ; 16(1): 30, 2023 Jul 06.

Artículo en Inglés | MEDLINE | ID: mdl-37415213

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