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1.

Identification of TIAM1 as a Potential Synthetic-Lethal-like Gene in a Defined Subset of Hepatocellular Carcinoma.

Permtermsin, Chalermsin; Lalchungnunga, H; Nakjang, Sirintra; Casement, John; Ogle, Laura Frances; Reeves, Helen L; Strathdee, Gordon; Shukla, Ruchi.

Int J Mol Sci ; 24(7)2023 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-37047360

2.

Genome wide DNA methylation analysis identifies novel molecular subgroups and predicts survival in neuroblastoma.

Lalchungnunga, H; Hao, Wen; Maris, John M; Asgharzadeh, Shahab; Henrich, Kai-Oliver; Westermann, Frank; Tweddle, Deborah A; Schwalbe, Edward C; Strathdee, Gordon.

Br J Cancer ; 127(11): 2006-2015, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-36175618

3.

Anti-cancer therapy is associated with long-term epigenomic changes in childhood cancer survivors.

Robinson, Natassia; Casement, John; Gunter, Marc J; Huybrechts, Inge; Agudo, Antonio; Barranco, Miguel Rodríguez; Eichelmann, Fabian; Johnson, Theron; Kaaks, Rudolf; Pala, Valeria; Panico, Salvatore; Sandanger, Torkjel M; Schultze, Matthias B; Travis, Ruth C; Tumino, Rosario; Vineis, Paolo; Weiderpass, Elisabete; Skinner, Roderick; Sharp, Linda; McKay, Jill A; Strathdee, Gordon.

Br J Cancer ; 127(2): 288-300, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35354948

4.

Epigenome-wide analysis reveals functional modulators of drug sensitivity and post-treatment survival in chronic lymphocytic leukaemia.

Barrow, Timothy M; Nakjang, Sirintra; Lafta, Fadhel; Bilotkach, Kateryna; Woodhouse, Laura; Junge, Gesa; Tudhope, Susan J; Wallis, Jonathan P; Marr, Helen; Marshall, Scott; Bown, Nick; Willmore, Elaine; Strathdee, Gordon.

Br J Cancer ; 124(2): 474-483, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33082556

5.

Analysis of retrotransposon subfamily DNA methylation reveals novel early epigenetic changes in chronic lymphocytic leukemia.

Barrow, Timothy M; Wong Doo, Nicole; Milne, Roger L; Giles, Graham G; Willmore, Elaine; Strathdee, Gordon; Byun, Hyang-Min.

Haematologica ; 106(1): 98-110, 2021 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-31919093

6.

Exploring a potential mechanistic role of DNA methylation in the relationship between in utero and post-natal environmental exposures and risk of childhood acute lymphoblastic leukaemia.

Timms, Jessica A; Relton, Caroline L; Sharp, Gemma C; Rankin, Judith; Strathdee, Gordon; McKay, Jill A.

Int J Cancer ; 145(11): 2933-2943, 2019 12 01.

Artículo en Inglés | MEDLINE | ID: mdl-30740682

7.

DNA methylation abnormalities at gene promoters are extensive and variable in the elderly and phenocopy cancer cells.

Gautrey, Hannah E; van Otterdijk, Sanne D; Cordell, Heather J; Mathers, John C; Strathdee, Gordon.

FASEB J ; 28(7): 3261-72, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24858281

8.

Acquisition of aberrant DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study.

Collerton, Joanna; Gautrey, Hannah E; van Otterdijk, Sanne D; Davies, Karen; Martin-Ruiz, Carmen; von Zglinicki, Thomas; Kirkwood, Thomas B L; Jagger, Carol; Mathers, John C; Strathdee, Gordon.

Biogerontology ; 15(4): 317-28, 2014 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-24770842

9.

Do age-related changes in DNA methylation play a role in the development of age-related diseases?

van Otterdijk, Sanne D; Mathers, John C; Strathdee, Gordon.

Biochem Soc Trans ; 41(3): 803-7, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23697941

10.

BCR-ABL1 tyrosine kinase sustained MECOM expression in chronic myeloid leukaemia.

Roy, Swagata; Jørgensen, Heather G; Roy, Poornima; Abed El Baky, Mohamed; Melo, Junia V; Strathdee, Gordon; Holyoake, Tessa L; Bartholomew, Chris.

Br J Haematol ; 157(4): 446-56, 2012 May.

Artículo en Inglés | MEDLINE | ID: mdl-22372463

11.

Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity.

Thathia, Shabnam H; Ferguson, Stuart; Gautrey, Hannah E; van Otterdijk, Sanne D; Hili, Michela; Rand, Vikki; Moorman, Anthony V; Meyer, Stefan; Brown, Robert; Strathdee, Gordon.

Haematologica ; 97(3): 371-8, 2012 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-22058208

12.

The dual role of HLXB9 in leukemia.

Ferguson, Stuart; Gautrey, Hannah E; Strathdee, Gordon.

Pediatr Blood Cancer ; 56(3): 349-52, 2011 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-21069786

13.

Integration of genome-level data to allow identification of subtype-specific vulnerability genes as novel therapeutic targets.

Schwalbe, Edward C; H, Lalchungnunga; Lafta, Fadhel; Barrow, Timothy M; Strathdee, Gordon.

Oncogene ; 40(33): 5213-5223, 2021 08.

Artículo en Inglés | MEDLINE | ID: mdl-34230614

14.

Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia.

Lin, Wei-Yu; Fordham, Sarah E; Sunter, Nicola; Elstob, Claire; Rahman, Thahira; Willmore, Elaine; Shepherd, Colin; Strathdee, Gordon; Mainou-Fowler, Tryfonia; Piddock, Rachel; Mearns, Hannah; Barrow, Timothy; Houlston, Richard S; Marr, Helen; Wallis, Jonathan; Summerfield, Geoffrey; Marshall, Scott; Pettitt, Andrew; Pepper, Christopher; Fegan, Christopher; Forconi, Francesco; Dyer, Martin J S; Jayne, Sandrine; Sellors, April; Schuh, Anna; Robbe, Pauline; Oscier, David; Bailey, James; Rais, Syed; Bentley, Alison; Cawkwell, Lynn; Evans, Paul; Hillmen, Peter; Pratt, Guy; Allsup, David J; Allan, James M.

Nat Commun ; 12(1): 665, 2021 01 28.

Artículo en Inglés | MEDLINE | ID: mdl-33510140

15.

Inactivation of HOXA genes by hypermethylation in myeloid and lymphoid malignancy is frequent and associated with poor prognosis.

Strathdee, Gordon; Holyoake, Tessa L; Sim, Alyson; Parker, Anton; Oscier, David G; Melo, Junia V; Meyer, Stefan; Eden, Tim; Dickinson, Anne M; Mountford, Joanne C; Jorgensen, Heather G; Soutar, Richard; Brown, Robert.

Clin Cancer Res ; 13(17): 5048-55, 2007 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-17785556

16.

Maternal Red Blood Cell Folate and Infant Vitamin B₁₂ Status Influence Methylation of Genes Associated with Childhood Acute Lymphoblastic Leukemia.

Potter, Catherine; Moorman, Anthony Vincent; Relton, Caroline Laura; Ford, Dianne; Mathers, John Cummings; Strathdee, Gordon; McKay, Jill Ann.

Mol Nutr Food Res ; 62(22): e1800411, 2018 11.

Artículo en Inglés | MEDLINE | ID: mdl-30192066

17.

Epigenetic markers and response to chemotherapy in cancer.

Strathdee, Gordon.

Dis Markers ; 23(1-2): 43-9, 2007.

Artículo en Inglés | MEDLINE | ID: mdl-17325425

18.

CpG island methylation of DNA damage response genes in advanced ovarian cancer.

Teodoridis, Jens M; Hall, Jacqueline; Marsh, Sharon; Kannall, Hilary D; Smyth, Catriona; Curto, Jorge; Siddiqui, Nadeem; Gabra, Hani; McLeod, Howard L; Strathdee, Gordon; Brown, Robert.

Cancer Res ; 65(19): 8961-7, 2005 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-16204069

19.

DNA methylation as a potential mediator of environmental risks in the development of childhood acute lymphoblastic leukemia.

Timms, Jessica A; Relton, Caroline L; Rankin, Judith; Strathdee, Gordon; McKay, Jill A.

Epigenomics ; 8(4): 519-36, 2016 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-27035209

20.

Epigenomics and epigenetic therapy of cancer.

Brown, Robert; Strathdee, Gordon.

Trends Mol Med ; 8(4 Suppl): S43-8, 2002.

Artículo en Inglés | MEDLINE | ID: mdl-11927287

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