Búsqueda | Portal de Búsqueda de la BVS

1.

A Synergistic Interaction between Chk1- and MK2 Inhibitors in KRAS-Mutant Cancer.

Dietlein, Felix; Kalb, Bastian; Jokic, Mladen; Noll, Elisa M; Strong, Alexander; Tharun, Lars; Ozretic, Luka; Künstlinger, Helen; Kambartel, Kato; Randerath, Winfried J; Jüngst, Christian; Schmitt, Anna; Torgovnick, Alessandro; Richters, André; Rauh, Daniel; Siedek, Florian; Persigehl, Thorsten; Mauch, Cornelia; Bartkova, Jirina; Bradley, Allan; Sprick, Martin R; Trumpp, Andreas; Rad, Roland; Saur, Dieter; Bartek, Jiri; Wolf, Jürgen; Büttner, Reinhard; Thomas, Roman K; Reinhardt, H Christian.

Cell ; 162(1): 146-59, 2015 Jul 02.

Artículo en Inglés | MEDLINE | ID: mdl-26140595

2.

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.

Imielinski, Marcin; Berger, Alice H; Hammerman, Peter S; Hernandez, Bryan; Pugh, Trevor J; Hodis, Eran; Cho, Jeonghee; Suh, James; Capelletti, Marzia; Sivachenko, Andrey; Sougnez, Carrie; Auclair, Daniel; Lawrence, Michael S; Stojanov, Petar; Cibulskis, Kristian; Choi, Kyusam; de Waal, Luc; Sharifnia, Tanaz; Brooks, Angela; Greulich, Heidi; Banerji, Shantanu; Zander, Thomas; Seidel, Danila; Leenders, Frauke; Ansén, Sascha; Ludwig, Corinna; Engel-Riedel, Walburga; Stoelben, Erich; Wolf, Jürgen; Goparju, Chandra; Thompson, Kristin; Winckler, Wendy; Kwiatkowski, David; Johnson, Bruce E; Jänne, Pasi A; Miller, Vincent A; Pao, William; Travis, William D; Pass, Harvey I; Gabriel, Stacey B; Lander, Eric S; Thomas, Roman K; Garraway, Levi A; Getz, Gad; Meyerson, Matthew.

Cell ; 150(6): 1107-20, 2012 Sep 14.

Artículo en Inglés | MEDLINE | ID: mdl-22980975

3.

Retraction Notice to: Cytohesins Are Cytoplasmic ErbB Receptor Activators.

Bill, Anke; Schmitz, Anton; Albertoni, Barbara; Song, Jin-Na; Heukamp, Lukas C; Walrafen, David; Thorwirth, Franziska; Verveer, Peter J; Zimmer, Sebastian; Meffert, Lisa; Schreiber, Arne; Chatterjee, Sampurna; Thomas, Roman K; Ullrich, Roland T; Lang, Thorsten; Famulok, Michael.

Cell ; 165(5): 1293, 2016 May 19.

Artículo en Inglés | MEDLINE | ID: mdl-27203114

4.

Cytohesins are cytoplasmic ErbB receptor activators.

Bill, Anke; Schmitz, Anton; Albertoni, Barbara; Song, Jin-Na; Heukamp, Lukas C; Walrafen, David; Thorwirth, Franziska; Verveer, Peter J; Zimmer, Sebastian; Meffert, Lisa; Schreiber, Arne; Chatterjee, Sampurna; Thomas, Roman K; Ullrich, Roland T; Lang, Thorsten; Famulok, Michael.

Cell ; 143(2): 201-11, 2010 Oct 15.

Artículo en Inglés | MEDLINE | ID: mdl-20946980

5.

Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death.

Baumert, Hannah Maria; Metzger, Eric; Fahrner, Matthias; George, Julie; Thomas, Roman K; Schilling, Oliver; Schüle, Roland.

Cancer Cell Int ; 20: 52, 2020.

Artículo en Inglés | MEDLINE | ID: mdl-32095117

6.

AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.

Höpker, Katja; Hagmann, Henning; Khurshid, Safiya; Chen, Shuhua; Hasskamp, Pia; Seeger-Nukpezah, Tamina; Schilberg, Katharina; Heukamp, Lukas; Lamkemeyer, Tobias; Sos, Martin L; Thomas, Roman K; Lowery, Drew; Roels, Frederik; Fischer, Matthias; Liebau, Max C; Resch, Ulrike; Kisner, Tülay; Röther, Fabian; Bartram, Malte P; Müller, Roman Ulrich; Fabretti, Francesca; Kurschat, Peter; Schumacher, Björn; Gaestel, Matthias; Medema, René H; Yaffe, Michael B; Schermer, Bernhard; Reinhardt, H Christian; Benzing, Thomas.

EMBO J ; 31(20): 3961-75, 2012 Oct 17.

Artículo en Inglés | MEDLINE | ID: mdl-22909821

7.

High-throughput oncogene mutation profiling in human cancer.

Thomas, Roman K; Baker, Alissa C; Debiasi, Ralph M; Winckler, Wendy; Laframboise, Thomas; Lin, William M; Wang, Meng; Feng, Whei; Zander, Thomas; MacConaill, Laura; Macconnaill, Laura E; Lee, Jeffrey C; Nicoletti, Rick; Hatton, Charlie; Goyette, Mary; Girard, Luc; Majmudar, Kuntal; Ziaugra, Liuda; Wong, Kwok-Kin; Gabriel, Stacey; Beroukhim, Rameen; Peyton, Michael; Barretina, Jordi; Dutt, Amit; Emery, Caroline; Greulich, Heidi; Shah, Kinjal; Sasaki, Hidefumi; Gazdar, Adi; Minna, John; Armstrong, Scott A; Mellinghoff, Ingo K; Hodi, F Stephen; Dranoff, Glenn; Mischel, Paul S; Cloughesy, Tim F; Nelson, Stan F; Liau, Linda M; Mertz, Kirsten; Rubin, Mark A; Moch, Holger; Loda, Massimo; Catalona, William; Fletcher, Jonathan; Signoretti, Sabina; Kaye, Frederic; Anderson, Kenneth C; Demetri, George D; Dummer, Reinhard; Wagner, Stephan.

Nat Genet ; 39(3): 347-51, 2007 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-17293865

8.

CGARS: cancer genome analysis by rank sums.

Lu, Xin; Thomas, Roman K; Peifer, Martin.

Bioinformatics ; 30(9): 1295-6, 2014 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-24413525

9.

Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy.

Li, Danan; Shimamura, Takeshi; Ji, Hongbin; Chen, Liang; Haringsma, Henry J; McNamara, Kate; Liang, Mei-Chih; Perera, Samanthi A; Zaghlul, Sara; Borgman, Christa L; Kubo, Shigeto; Takahashi, Masaya; Sun, Yanping; Chirieac, Lucian R; Padera, Robert F; Lindeman, Neal I; Jänne, Pasi A; Thomas, Roman K; Meyerson, Matthew L; Eck, Michael J; Engelman, Jeffrey A; Shapiro, Geoffrey I; Wong, Kwok-Kin.

Cancer Cell ; 12(1): 81-93, 2007 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-17613438

10.

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.

Barbie, David A; Tamayo, Pablo; Boehm, Jesse S; Kim, So Young; Moody, Susan E; Dunn, Ian F; Schinzel, Anna C; Sandy, Peter; Meylan, Etienne; Scholl, Claudia; Fröhling, Stefan; Chan, Edmond M; Sos, Martin L; Michel, Kathrin; Mermel, Craig; Silver, Serena J; Weir, Barbara A; Reiling, Jan H; Sheng, Qing; Gupta, Piyush B; Wadlow, Raymond C; Le, Hanh; Hoersch, Sebastian; Wittner, Ben S; Ramaswamy, Sridhar; Livingston, David M; Sabatini, David M; Meyerson, Matthew; Thomas, Roman K; Lander, Eric S; Mesirov, Jill P; Root, David E; Gilliland, D Gary; Jacks, Tyler; Hahn, William C.

Nature ; 462(7269): 108-12, 2009 Nov 05.

Artículo en Inglés | MEDLINE | ID: mdl-19847166

11.

A framework for identification of actionable cancer genome dependencies in small cell lung cancer.

Sos, Martin L; Dietlein, Felix; Peifer, Martin; Schöttle, Jakob; Balke-Want, Hyatt; Müller, Christian; Koker, Mirjam; Richters, André; Heynck, Stefanie; Malchers, Florian; Heuckmann, Johannes M; Seidel, Danila; Eyers, Patrick A; Ullrich, Roland T; Antonchick, Andrey P; Vintonyak, Viktor V; Schneider, Peter M; Ninomiya, Takashi; Waldmann, Herbert; Büttner, Reinhard; Rauh, Daniel; Heukamp, Lukas C; Thomas, Roman K.

Proc Natl Acad Sci U S A ; 109(42): 17034-9, 2012 Oct 16.

Artículo en Inglés | MEDLINE | ID: mdl-23035247

12.

Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing.

Thomas, Roman K; Nickerson, Elizabeth; Simons, Jan F; Jänne, Pasi A; Tengs, Torstein; Yuza, Yuki; Garraway, Levi A; LaFramboise, Thomas; Lee, Jeffrey C; Shah, Kinjal; O'Neill, Keith; Sasaki, Hidefumi; Lindeman, Neal; Wong, Kwok-Kin; Borras, Ana M; Gutmann, Edward J; Dragnev, Konstantin H; DeBiasi, Ralph; Chen, Tzu-Hsiu; Glatt, Karen A; Greulich, Heidi; Desany, Brian; Lubeski, Christine K; Brockman, William; Alvarez, Pablo; Hutchison, Stephen K; Leamon, J H; Ronan, Michael T; Turenchalk, Gregory S; Egholm, Michael; Sellers, William R; Rothberg, Jonathan M; Meyerson, Matthew.

Nat Med ; 12(7): 852-5, 2006 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-16799556

13.

Characterizing the cancer genome in lung adenocarcinoma.

Weir, Barbara A; Woo, Michele S; Getz, Gad; Perner, Sven; Ding, Li; Beroukhim, Rameen; Lin, William M; Province, Michael A; Kraja, Aldi; Johnson, Laura A; Shah, Kinjal; Sato, Mitsuo; Thomas, Roman K; Barletta, Justine A; Borecki, Ingrid B; Broderick, Stephen; Chang, Andrew C; Chiang, Derek Y; Chirieac, Lucian R; Cho, Jeonghee; Fujii, Yoshitaka; Gazdar, Adi F; Giordano, Thomas; Greulich, Heidi; Hanna, Megan; Johnson, Bruce E; Kris, Mark G; Lash, Alex; Lin, Ling; Lindeman, Neal; Mardis, Elaine R; McPherson, John D; Minna, John D; Morgan, Margaret B; Nadel, Mark; Orringer, Mark B; Osborne, John R; Ozenberger, Brad; Ramos, Alex H; Robinson, James; Roth, Jack A; Rusch, Valerie; Sasaki, Hidefumi; Shepherd, Frances; Sougnez, Carrie; Spitz, Margaret R; Tsao, Ming-Sound; Twomey, David; Verhaak, Roel G W; Weinstock, George M.

Nature ; 450(7171): 893-8, 2007 Dec 06.

Artículo en Inglés | MEDLINE | ID: mdl-17982442

14.

Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.

Chmielecki, Juliann; Peifer, Martin; Viale, Agnes; Hutchinson, Katherine; Giltnane, Jennifer; Socci, Nicholas D; Hollis, Clayton J; Dean, Rebecca S; Yenamandra, Ashwini; Jagasia, Madan; Kim, Annette S; Davé, Utpal P; Thomas, Roman K; Pao, William.

Genes Chromosomes Cancer ; 51(1): 54-65, 2012 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-21938754

15.

Counteracting lineage-specific transcription factor network finely tunes lung adeno-to-squamous transdifferentiation through remodeling tumor immune microenvironment.

Tang, Shijie; Xue, Yun; Qin, Zhen; Fang, Zhaoyuan; Sun, Yihua; Yuan, Chongzhe; Pan, Yunjian; Zhao, Yue; Tong, Xinyuan; Zhang, Jian; Huang, Hsinyi; Chen, Yuting; Hu, Liang; Huang, Dasong; Wang, Ruiqi; Zou, Weiguo; Li, Yuan; Thomas, Roman K; Ventura, Andrea; Wong, Kwok-Kin; Chen, Haiquan; Chen, Luonan; Ji, Hongbin.

Natl Sci Rev ; 10(4): nwad028, 2023 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-37051524

16.

Characterizing Evolutionary Dynamics Reveals Strategies to Exhaust the Spectrum of Subclonal Resistance in EGFR-Mutant Lung Cancer.

Müller, Nina; Lorenz, Carina; Ostendorp, Jenny; Heisel, Felix S; Friese, Ulrich P; Cartolano, Maria; Plenker, Dennis; Tumbrink, Hannah; Heimsoeth, Alena; Baedeker, Philipp; Weiss, Jonathan; Ortiz-Cuaran, Sandra; Büttner, Reinhard; Peifer, Martin; Thomas, Roman K; Sos, Martin L; Berg, Johannes; Brägelmann, Johannes.

Cancer Res ; 83(15): 2471-2479, 2023 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-37289018

17.

Correction to: Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis.

Jin, Yujuan; Zhao, Qiqi; Zhu, Weikang; Feng, Yan; Xiao, Tian; Zhang, Peng; Jiang, Liyan; Hou, Yingyong; Guo, Chenchen; Huang, Hsinyi; Chen, Yabin; Tong, Xinyuan; Cao, Jiayu; Li, Fei; Zhu, Xueliang; Qin, Jun; Gao, Dong; Liu, Xin-Yuan; Zhang, Hua; Chen, Luonan; Thomas, Roman K; Wong, Kwok-Kin; Zhang, Lei; Wang, Yong; Hu, Liang; Ji, Hongbin.

Natl Sci Rev ; 10(12): nwac224, 2023 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-38155833

18.

Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies.

Flümann, Ruth; Hansen, Julia; Pelzer, Benedikt W; Nieper, Pascal; Lohmann, Tim; Kisis, Ilmars; Riet, Tobias; Kohlhas, Viktoria; Nguyen, Phuong-Hien; Peifer, Martin; Abedpour, Nima; Bosco, Graziella; Thomas, Roman K; Kochanek, Moritz; Knüfer, Jacqueline; Jonigkeit, Lorenz; Beleggia, Filippo; Holzem, Alessandra; Büttner, Reinhard; Lohneis, Philipp; Meinel, Jörn; Ortmann, Monika; Persigehl, Thorsten; Hallek, Michael; Calado, Dinis Pedro; Chmielewski, Markus; Klein, Sebastian; Göthert, Joachim R; Chapuy, Bjoern; Zevnik, Branko; Wunderlich, F Thomas; von Tresckow, Bastian; Jachimowicz, Ron D; Melnick, Ari M; Reinhardt, Hans Christian; Knittel, Gero.

Blood Cancer Discov ; 4(1): 78-97, 2023 01 06.

Artículo en Inglés | MEDLINE | ID: mdl-36346827

19.

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer.

Malchers, Florian; Nogova, Lucia; van Attekum, Martijn Ha; Maas, Lukas; Brägelmann, Johannes; Bartenhagen, Christoph; Girard, Luc; Bosco, Graziella; Dahmen, Ilona; Michels, Sebastian; Weeden, Clare E; Scheel, Andreas H; Meder, Lydia; Golfmann, Kristina; Schuldt, Philipp; Siemanowski, Janna; Rehker, Jan; Merkelbach-Bruse, Sabine; Menon, Roopika; Gautschi, Oliver; Heuckmann, Johannes M; Brambilla, Elisabeth; Asselin-Labat, Marie-Liesse; Persigehl, Thorsten; Minna, John D; Walczak, Henning; Ullrich, Roland T; Fischer, Matthias; Reinhardt, Hans Christian; Wolf, Jürgen; Büttner, Reinhard; Peifer, Martin; George, Julie; Thomas, Roman K.

J Clin Invest ; 133(21)2023 11 01.

Artículo en Inglés | MEDLINE | ID: mdl-37606995

20.

Overcoming drug resistance in ALK-rearranged lung cancer.

Thomas, Roman K.

N Engl J Med ; 370(13): 1250-1, 2014 Mar 27.

Artículo en Inglés | MEDLINE | ID: mdl-24670172

Portal de Búsqueda de la BVS

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar: