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1.

Topical Application of ASN008, a Permanently Charged Sodium Channel Blocker, Shows Robust Efficacy, a Rapid Onset, and Long Duration of Action in a Mouse Model of Pruritus.

Ramachandran, Roshni; Thompson, Scott K; Malkmus, Shelle; Mieda, Tsutomu; Lin, Jun-Hsiang; Gupta, Sandeep; Yaksh, Tony L.

J Pharmacol Exp Ther ; 374(3): 521-528, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32616515

2.

Improving the developability profile of pyrrolidine progesterone receptor partial agonists.

Kallander, Lara S; Washburn, David G; Hoang, Tram H; Frazee, James S; Stoy, Patrick; Johnson, Latisha; Lu, Qing; Hammond, Marlys; Barton, Linda S; Patterson, Jaclyn R; Azzarano, Leonard M; Nagilla, Rakesh; Madauss, Kevin P; Williams, Shawn P; Stewart, Eugene L; Duraiswami, Chaya; Grygielko, Eugene T; Xu, Xiaoping; Laping, Nicholas J; Bray, Jeffrey D; Thompson, Scott K.

Bioorg Med Chem Lett ; 20(1): 371-4, 2010 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-19926282

3.

Synthesis and SAR of potent LXR agonists containing an indole pharmacophore.

Washburn, David G; Hoang, Tram H; Campobasso, Nino; Smallwood, Angela; Parks, Derek J; Webb, Christine L; Frank, Kelly A; Nord, Melanie; Duraiswami, Chaya; Evans, Christopher; Jaye, Michael; Thompson, Scott K.

Bioorg Med Chem Lett ; 19(4): 1097-100, 2009 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-19167885

4.

The discovery of tertiary-amine LXR agonists with potent cholesterol efflux activity in macrophages.

Marino, Joseph P; Kallander, Lara S; Ma, Chun; Oh, Hye-Ja; Lee, Dennis; Gaitanopoulos, Dimitri E; Krawiec, John A; Parks, Derek J; Webb, Christine L; Ziegler, Kelly; Jaye, Michael; Thompson, Scott K.

Bioorg Med Chem Lett ; 19(19): 5617-21, 2009 Oct 01.

Artículo en Inglés | MEDLINE | ID: mdl-19717304

5.

Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists.

Hammond, Marlys; Patterson, Jaclyn R; Manns, Sharada; Hoang, Tram H; Washburn, David G; Trizna, Walter; Glace, Lindsay; Grygielko, Eugene T; Nagilla, Rakesh; Nord, Melanie; Fries, Harvey E; Minick, Douglas J; Laping, Nicholas J; Bray, Jeffrey D; Thompson, Scott K.

Bioorg Med Chem Lett ; 19(10): 2637-41, 2009 May 15.

Artículo en Inglés | MEDLINE | ID: mdl-19376703

6.

2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.

Wang, Yonghui; Duraiswami, Chaya; Madauss, Kevin P; Tran, Thuy B; Williams, Shawn P; Deng, Su-Jun; Graybill, Todd L; Hammond, Marlys; Jones, David G; Grygielko, Eugene T; Bray, Jeffrey D; Thompson, Scott K.

Bioorg Med Chem Lett ; 19(17): 4916-9, 2009 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-19664922

7.

Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists.

Thompson, Scott K; Washburn, David G; Frazee, James S; Madauss, Kevin P; Hoang, Tram H; Lapinski, Leahann; Grygielko, Eugene T; Glace, Lindsay E; Trizna, Walter; Williams, Shawn P; Duraiswami, Chaya; Bray, Jeffrey D; Laping, Nicholas J.

Bioorg Med Chem Lett ; 19(16): 4777-80, 2009 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-19595590

8.

Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.

Hammond, Marlys; Washburn, David G; Hoang, H Tram; Manns, Sharada; Frazee, James S; Nakamura, Hiroko; Patterson, Jaclyn R; Trizna, Walter; Wu, Charlene; Azzarano, Leonard M; Nagilla, Rakesh; Nord, Melanie; Trejo, Rebecca; Head, Martha S; Zhao, Baoguang; Smallwood, Angela M; Hightower, Kendra; Laping, Nicholas J; Schnackenberg, Christine G; Thompson, Scott K.

Bioorg Med Chem Lett ; 19(15): 4441-5, 2009 Aug 01.

Artículo en Inglés | MEDLINE | ID: mdl-19497745

9.

Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists.

Washburn, David G; Hoang, Tram H; Frazee, James S; Johnson, Latisha; Hammond, Marlys; Manns, Sharada; Madauss, Kevin P; Williams, Shawn P; Duraiswami, Chaya; Tran, Thuy B; Stewart, Eugene L; Grygielko, Eugene T; Glace, Lindsay E; Trizna, Walter; Nagilla, Rakesh; Bray, Jeffrey D; Thompson, Scott K.

Bioorg Med Chem Lett ; 19(16): 4664-8, 2009 Aug 15.

Artículo en Inglés | MEDLINE | ID: mdl-19616429

10.

A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator.

Madauss, Kevin P; Grygielko, Eugene T; Deng, Su-Jun; Sulpizio, Anthony C; Stanley, Thomas B; Wu, Charlene; Short, Steve A; Thompson, Scott K; Stewart, Eugene L; Laping, Nicholas J; Williams, Shawn P; Bray, Jeffrey D.

Mol Endocrinol ; 21(5): 1066-81, 2007 May.

Artículo en Inglés | MEDLINE | ID: mdl-17356170

11.

Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore.

Marino, Joseph P; Fisher, Paul W; Hofmann, Glenn A; Kirkpatrick, Robert B; Janson, Cheryl A; Johnson, Randall K; Ma, Chun; Mattern, Michael; Meek, Thomas D; Ryan, M Dominic; Schulz, Christina; Smith, Ward W; Tew, David G; Tomazek, Thaddeus A; Veber, Daniel F; Xiong, Wenfang C; Yamamoto, Yuuichi; Yamashita, Keizo; Yang, Guang; Thompson, Scott K.

J Med Chem ; 50(16): 3777-85, 2007 Aug 09.

Artículo en Inglés | MEDLINE | ID: mdl-17636946

12.

Estrogen blockade reduces auditory feedback in CBA mice.

Thompson, Scott K; Zhu, Xiaoxia; Frisina, Robert D.

Otolaryngol Head Neck Surg ; 135(1): 100-5, 2006 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-16815192

13.

Microtia reconstruction.

Quatela, Vito C; Thompson, Scott K; Goldman, Neal D.

Facial Plast Surg Clin North Am ; 14(2): 117-27, vi, 2006 May.

Artículo en Inglés | MEDLINE | ID: mdl-16750769

14.

4-Aryl-1,2,3-triazole: a novel template for a reversible methionine aminopeptidase 2 inhibitor, optimized to inhibit angiogenesis in vivo.

Kallander, Lara S; Lu, Qing; Chen, Wenfang; Tomaszek, Thaddeus; Yang, Guang; Tew, David; Meek, Thomas D; Hofmann, Glenn A; Schulz-Pritchard, Christina K; Smith, Ward W; Janson, Cheryl A; Ryan, M Dominic; Zhang, Gui-Feng; Johanson, Kyung O; Kirkpatrick, Robert B; Ho, Thau F; Fisher, Paul W; Mattern, Michael R; Johnson, Randall K; Hansbury, Michael J; Winkler, James D; Ward, Keith W; Veber, Daniel F; Thompson, Scott K.

J Med Chem ; 48(18): 5644-7, 2005 Sep 08.

Artículo en Inglés | MEDLINE | ID: mdl-16134930

15.

Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.

Jaye, Michael C; Krawiec, John A; Campobasso, Nino; Smallwood, Angela; Qiu, Chunyan; Lu, Quinn; Kerrigan, John J; De Los Frailes Alvaro, Maite; Laffitte, Bryan; Liu, Wu-Schyong; Marino, Joseph P; Meyer, Craig R; Nichols, Jason A; Parks, Derek J; Perez, Paloma; Sarov-Blat, Lea; Seepersaud, Sheila D; Steplewski, Klaudia M; Thompson, Scott K; Wang, Ping; Watson, Mike A; Webb, Christine L; Haigh, David; Caravella, Justin A; Macphee, Colin H; Willson, Timothy M; Collins, Jon L.

J Med Chem ; 48(17): 5419-22, 2005 Aug 25.

Artículo en Inglés | MEDLINE | ID: mdl-16107141

16.

Infectious mononucleosis and corticosteroids: management practices and outcomes.

Thompson, Scott K; Doerr, Timothy D; Hengerer, Arthur S.

Arch Otolaryngol Head Neck Surg ; 131(10): 900-4, 2005 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-16230594

17.

External auditory canal foreign body removal: management practices and outcomes.

Thompson, Scott K; Wein, Richard O; Dutcher, Paul O.

Laryngoscope ; 113(11): 1912-5, 2003 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-14603046

18.

Submental rhytidoplasty following rhytidectomy and platysmaplasty.

Quatela, Vito; Thompson, Scott K; Congdon, David J.

Ear Nose Throat J ; 83(2): 94-5, 2004 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-15008442

19.

Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

Sherk, Andrea B; Frigo, Daniel E; Schnackenberg, Christine G; Bray, Jeffrey D; Laping, Nicholas J; Trizna, Walter; Hammond, Marlys; Patterson, Jaclyn R; Thompson, Scott K; Kazmin, Dmitri; Norris, John D; McDonnell, Donald P.

Cancer Res ; 68(18): 7475-83, 2008 Sep 15.

Artículo en Inglés | MEDLINE | ID: mdl-18794135

20.

Discovery of non-steroidal mifepristone mimetics: pyrazoline-based PR antagonists.

Jones, David G; Liang, Xi; Stewart, Eugene L; Noe, Robert A; Kallander, Lara S; Madauss, Kevin P; Williams, Shawn P; Thompson, Scott K; Gray, David W; Hoekstra, William J.

Bioorg Med Chem Lett ; 15(13): 3203-6, 2005 Jul 01.

Artículo en Inglés | MEDLINE | ID: mdl-15925510

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