Detalles de la búsqueda
1.
Pyrrolidinyl phenylurea derivatives as novel CCR3 antagonists.
Bioorg Med Chem Lett
; 22(22): 6876-81, 2012 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23046963
2.
Discovery and structure-activity relationships of urea derivatives as potent and novel CCR3 antagonists.
Bioorg Med Chem Lett
; 22(15): 4951-4, 2012 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22749826
3.
Synthesis and biological evaluation of (4H-1,2,4-triazol-4-yl)isoquinoline derivatives as selective glycine transporter 1 inhibitors.
Bioorg Med Chem
; 20(1): 34-41, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22177408
4.
Synthesis and pharmacological evaluation of 2-(1-alkylpiperidin-4-yl)-n-[(1r)-1-(4-fluorophenyl)-2-methylpropyl]acetamide Derivatives as Novel Antihypertensive Agents.
Chem Pharm Bull (Tokyo)
; 60(2): 223-34, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22293482
5.
Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.
Bioorg Med Chem
; 19(18): 5628-38, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21875808
6.
Synthesis and pharmacological evaluation of 1-isopropyl-1,2,3,4-tetrahydroisoquinoline derivatives as novel antihypertensive agents.
Chem Pharm Bull (Tokyo)
; 59(8): 1029-37, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21804249
7.
Synthesis and pharmacological evaluation of 1-alkyl-N-[(1R)-1-(4-fluorophenyl)-2-methylpropyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents.
Chem Pharm Bull (Tokyo)
; 59(11): 1376-85, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-22041074
8.
Synthesis and structure-activity relationships of amide derivatives of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetic acid as selective arginine vasopressin V2 receptor agonists.
Bioorg Med Chem
; 17(8): 3130-41, 2009 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19321349
9.
Synthesis, biological evaluation, and metabolic stability of acrylamide derivatives as novel CCR3 antagonists.
Bioorg Med Chem
; 17(16): 5989-6002, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19620010
10.
Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes.
Bioorg Med Chem
; 17(24): 8161-7, 2009 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19900813
11.
Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors.
Bioorg Med Chem
; 17(19): 6926-36, 2009 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19747833
12.
Synthesis and pharmacological evaluation of bis-3-(3,4-dichlorophenyl)acrylamide derivatives as glycogen phosphorylase inhibitors.
Bioorg Med Chem
; 16(18): 8627-34, 2008 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18723356
13.
Synthesis and structure-activity relationships of a series of benzazepine derivatives as 5-HT2C receptor agonists.
Bioorg Med Chem
; 16(6): 3309-20, 2008 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18083579
14.
Design and synthesis of 6-fluoro-2-naphthyl derivatives as novel CCR3 antagonists with reduced CYP2D6 inhibition.
Bioorg Med Chem
; 16(18): 8607-18, 2008 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18752960
15.
Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.
Bioorg Med Chem
; 16(23): 10001-12, 2008 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18952447
16.
Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors.
Bioorg Med Chem
; 16(13): 6509-21, 2008 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18534856
17.
Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a.
Bioorg Med Chem
; 16(10): 5452-64, 2008 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18434170
18.
Preparation of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetamide derivatives as novel arginine vasopressin V(2) receptor agonists.
Bioorg Med Chem
; 16(21): 9524-35, 2008 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18835174
19.
Synthesis and structure-activity relationships of N-{1-[(6-fluoro-2-naphthyl)methyl]piperidin-4-yl}benzamide derivatives as novel CCR3 antagonists.
Bioorg Med Chem
; 16(1): 144-56, 2008 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17951061
20.
Synthesis and structure-activity relationships of a series of substituted 2-(1H-furo[2,3-g]indazol-1-yl)ethylamine derivatives as 5-HT2C receptor agonists.
Bioorg Med Chem
; 16(4): 1966-82, 2008 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18035544