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1.

Beta cell-specific CD8⁺ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes.

Abdelsamed, Hossam A; Zebley, Caitlin C; Nguyen, Hai; Rutishauser, Rachel L; Fan, Yiping; Ghoneim, Hazem E; Crawford, Jeremy Chase; Alfei, Francesca; Alli, Shanta; Ribeiro, Susan Pereira; Castellaw, Ashley H; McGargill, Maureen A; Jin, Hongjian; Boi, Shannon K; Speake, Cate; Serti, Elisavet; Turka, Laurence A; Busch, Michael E; Stone, Mars; Deeks, Steven G; Sekaly, Rafick-Pierre; Zehn, Dietmar; James, Eddie A; Nepom, Gerald T; Youngblood, Ben.

Nat Immunol ; 21(5): 578-587, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-32231298

2.

Maintenance of CD4 T cell fitness through regulation of Foxo1.

Newton, Ryan H; Shrestha, Sharad; Sullivan, Jenna M; Yates, Kathleen B; Compeer, Ewoud B; Ron-Harel, Noga; Blazar, Bruce R; Bensinger, Steven J; Haining, W Nicholas; Dustin, Michael L; Campbell, Daniel J; Chi, Hongbo; Turka, Laurence A.

Nat Immunol ; 19(8): 838-848, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-29988091

3.

Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function.

Papa, Antonella; Wan, Lixin; Bonora, Massimo; Salmena, Leonardo; Song, Min Sup; Hobbs, Robin M; Lunardi, Andrea; Webster, Kaitlyn; Ng, Christopher; Newton, Ryan H; Knoblauch, Nicholas; Guarnerio, Jlenia; Ito, Keisuke; Turka, Laurence A; Beck, Andy H; Pinton, Paolo; Bronson, Roderick T; Wei, Wenyi; Pandolfi, Pier Paolo.

Cell ; 157(3): 595-610, 2014 Apr 24.

Artículo en Inglés | MEDLINE | ID: mdl-24766807

4.

Immunometabolism of regulatory T cells.

Newton, Ryan; Priyadharshini, Bhavana; Turka, Laurence A.

Nat Immunol ; 17(6): 618-25, 2016 05 19.

Artículo en Inglés | MEDLINE | ID: mdl-27196520

5.

Foxp3 and Toll-like receptor signaling balance T_reg cell anabolic metabolism for suppression.

Gerriets, Valerie A; Kishton, Rigel J; Johnson, Marc O; Cohen, Sivan; Siska, Peter J; Nichols, Amanda G; Warmoes, Marc O; de Cubas, Aguirre A; MacIver, Nancie J; Locasale, Jason W; Turka, Laurence A; Wells, Andrew D; Rathmell, Jeffrey C.

Nat Immunol ; 17(12): 1459-1466, 2016 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-27695003

6.

Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability.

Huynh, Alexandria; DuPage, Michel; Priyadharshini, Bhavana; Sage, Peter T; Quiros, Jason; Borges, Christopher M; Townamchai, Natavudh; Gerriets, Valerie A; Rathmell, Jeffrey C; Sharpe, Arlene H; Bluestone, Jeffrey A; Turka, Laurence A.

Nat Immunol ; 16(2): 188-96, 2015 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-25559257

7.

Mitochondrial complex III is essential for suppressive function of regulatory T cells.

Weinberg, Samuel E; Singer, Benjamin D; Steinert, Elizabeth M; Martinez, Carlos A; Mehta, Manan M; Martínez-Reyes, Inmaculada; Gao, Peng; Helmin, Kathryn A; Abdala-Valencia, Hiam; Sena, Laura A; Schumacker, Paul T; Turka, Laurence A; Chandel, Navdeep S.

Nature ; 565(7740): 495-499, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-30626970

8.

Donor antigen-specific regulatory T cell administration to recipients of live donor kidneys: A ONE Study consortium pilot trial.

Guinan, Eva C; Contreras-Ruiz, Laura; Crisalli, Kerry; Rickert, Charles; Rosales, Ivy; Makar, Robert; Colvin, Robert; Geissler, Edward K; Sawitzki, Birgit; Harden, Paul; Tang, Qizhi; Blancho, Giles; Turka, Laurence A; Markmann, James F.

Am J Transplant ; 23(12): 1872-1881, 2023 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-37422112

9.

Ex vivo generation of regulatory T cells from liver transplant recipients using costimulation blockade.

Shimozawa, Katsuyoshi; Contreras-Ruiz, Laura; Sousa, Sofia; Zhang, Ruan; Bhatia, Urvashi; Crisalli, Kerry C; Brennan, Lisa L; Turka, Laurence A; Markmann, James F; Guinan, Eva C.

Am J Transplant ; 22(2): 504-518, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34528383

10.

A breath of fresh aire.

Zhang, Ruan; Turka, Laurence A.

Immunity ; 39(3): 427-9, 2013 Sep 19.

Artículo en Inglés | MEDLINE | ID: mdl-24054325

11.

Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.

Han, Daehee; Walsh, Matthew C; Cejas, Pedro J; Dang, Nicholas N; Kim, Youngmi F; Kim, Jihyun; Charrier-Hisamuddin, Laetitia; Chau, Lillian; Zhang, Qin; Bittinger, Kyle; Bushman, Frederic D; Turka, Laurence A; Shen, Hao; Reizis, Boris; Defranco, Anthony L; Wu, Gary D; Choi, Yongwon.

Immunity ; 38(6): 1211-22, 2013 Jun 27.

Artículo en Inglés | MEDLINE | ID: mdl-23791643

12.

Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.

Sawitzki, Birgit; Harden, Paul N; Reinke, Petra; Moreau, Aurélie; Hutchinson, James A; Game, David S; Tang, Qizhi; Guinan, Eva C; Battaglia, Manuela; Burlingham, William J; Roberts, Ian S D; Streitz, Mathias; Josien, Régis; Böger, Carsten A; Scottà, Cristiano; Markmann, James F; Hester, Joanna L; Juerchott, Karsten; Braudeau, Cecile; James, Ben; Contreras-Ruiz, Laura; van der Net, Jeroen B; Bergler, Tobias; Caldara, Rossana; Petchey, William; Edinger, Matthias; Dupas, Nathalie; Kapinsky, Michael; Mutzbauer, Ingrid; Otto, Natalie M; Öllinger, Robert; Hernandez-Fuentes, Maria P; Issa, Fadi; Ahrens, Norbert; Meyenberg, Christoph; Karitzky, Sandra; Kunzendorf, Ulrich; Knechtle, Stuart J; Grinyó, Josep; Morris, Peter J; Brent, Leslie; Bushell, Andrew; Turka, Laurence A; Bluestone, Jeffrey A; Lechler, Robert I; Schlitt, Hans J; Cuturi, Maria C; Schlickeiser, Stephan; Friend, Peter J; Miloud, Tewfik.

Lancet ; 395(10237): 1627-1639, 2020 05 23.

Artículo en Inglés | MEDLINE | ID: mdl-32446407

13.

Anti-tumor effects of RTX-240: an engineered red blood cell expressing 4-1BB ligand and interleukin-15.

McArdel, Shannon L; Dugast, Anne-Sophie; Hoover, Maegan E; Bollampalli, Arjun; Hong, Enping; Castano, Zafira; Leonard, Shannon Curtis; Pawar, Sneha; Mellen, Jennifer; Muriuki, Kelvin; McLaughlin, Douglas C; Bayhi, Nicholas; Carpenter, Christopher L; Turka, Laurence A; Wickham, Thomas J; Elloul, Sivan.

Cancer Immunol Immunother ; 70(9): 2701-2719, 2021 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-34244816

14.

Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus.

Levitsky, Josh; Burrell, Bryna E; Kanaparthi, Sai; Turka, Laurence A; Kurian, Sunil; Sanchez-Fueyo, Alberto; Lozano, Juan J; Demetris, Anthony; Lesniak, Andrew; Kirk, Allan D; Stempora, Linda; Yang, Guang-Yu; Mathew, James M.

Hepatology ; 72(2): 569-583, 2020 08.

Artículo en Inglés | MEDLINE | ID: mdl-31721246

15.

The cytokines interleukin 27 and interferon-Î³ promote distinct Treg cell populations required to limit infection-induced pathology.

Hall, Aisling O'Hara; Beiting, Daniel P; Tato, Cristina; John, Beena; Oldenhove, Guillaume; Lombana, Claudia Gonzalez; Pritchard, Gretchen Harms; Silver, Jonathan S; Bouladoux, Nicolas; Stumhofer, Jason S; Harris, Tajie H; Grainger, John; Wojno, Elia D Tait; Wagage, Sagie; Roos, David S; Scott, Philip; Turka, Laurence A; Cherry, Sara; Reiner, Steven L; Cua, Daniel; Belkaid, Yasmine; Elloso, M Merle; Hunter, Christopher A.

Immunity ; 37(3): 511-23, 2012 Sep 21.

Artículo en Inglés | MEDLINE | ID: mdl-22981537

16.

Abatacept Targets T Follicular Helper and Regulatory T Cells, Disrupting Molecular Pathways That Regulate Their Proliferation and Maintenance.

Glatigny, Simon; Höllbacher, Barbara; Motley, Samantha J; Tan, Cathy; Hundhausen, Christian; Buckner, Jane H; Smilek, Dawn; Khoury, Samia J; Ding, Linna; Qin, Tielin; Pardo, Jorge; Nepom, Gerald T; Turka, Laurence A; Harris, Kristina M; Campbell, Daniel J; Bettelli, Estelle.

J Immunol ; 202(5): 1373-1382, 2019 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-30683697

17.

Advances in targeting co-inhibitory and co-stimulatory pathways in transplantation settings: the Yin to the Yang of cancer immunotherapy.

Kean, Leslie S; Turka, Laurence A; Blazar, Bruce R.

Immunol Rev ; 276(1): 192-212, 2017 03.

Artículo en Inglés | MEDLINE | ID: mdl-28258702

18.

Cutting Edge: TGF-ß and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets.

Priyadharshini, Bhavana; Loschi, Michael; Newton, Ryan H; Zhang, Jian-Wen; Finn, Kelsey K; Gerriets, Valerie A; Huynh, Alexandria; Rathmell, Jeffery C; Blazar, Bruce R; Turka, Laurence A.

J Immunol ; 201(8): 2215-2219, 2018 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-30209190

19.

Tumor Tolerance-Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin.

Marangoni, Francesco; Zhang, Ruan; Mani, Vinidhra; Thelen, Martin; Ali Akbar, Noor J; Warner, Ross D; Äijö, Tarmo; Zappulli, Valentina; Martinez, Gustavo J; Turka, Laurence A; Mempel, Thorsten R.

J Immunol ; 200(10): 3647-3661, 2018 05 15.

Artículo en Inglés | MEDLINE | ID: mdl-29661826

20.

Targeting PI3KÎ´ function for amelioration of murine chronic graft-versus-host disease.

Paz, Katelyn; Flynn, Ryan; Du, Jing; Tannheimer, Stacey; Johnson, Amy J; Dong, Shuai; Stark, Anne-Katrien; Okkenhaug, Klaus; Panoskaltsis-Mortari, Angela; Sage, Peter T; Sharpe, Arlene H; Luznik, Leo; Ritz, Jerome; Soiffer, Robert J; Cutler, Corey S; Koreth, John; Antin, Joseph H; Miklos, David B; MacDonald, Kelli P; Hill, Geoffrey R; Maillard, Ivan; Serody, Jonathan S; Murphy, William J; Munn, David H; Feser, Colby; Zaiken, Michael; Vanhaesebroeck, Bart; Turka, Laurence A; Byrd, John C; Blazar, Bruce R.

Am J Transplant ; 19(6): 1820-1830, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30748099

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