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1.
Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer.
Cell
; 173(4): 864-878.e29, 2018 05 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29681454
2.
Polycomb Group (PcG) Proteins and Human Cancers: Multifaceted Functions and Therapeutic Implications.
Med Res Rev
; 35(6): 1220-67, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26227500
3.
Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice.
Gastroenterology
; 147(4): 893-902.e2, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25016295
4.
Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice.
Biomed Chromatogr
; 29(5): 654-63, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25294254
5.
Preclinical evaluation of anticancer efficacy and pharmacological properties of FBA-TPQ, a novel synthetic makaluvamine analog.
Mar Drugs
; 10(5): 1138-1155, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22822362
6.
Tumor-Activated Benzothiazole Inhibitors of Stearoyl-CoA Desaturase.
J Med Chem
; 63(17): 9773-9786, 2020 09 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32787093
7.
Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy.
Cancer Res
; 78(19): 5656-5667, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30217928
8.
Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair.
J Med Chem
; 60(9): 3979-4001, 2017 05 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-28398755
9.
Inulanolide A as a new dual inhibitor of NFAT1-MDM2 pathway for breast cancer therapy.
Oncotarget
; 7(22): 32566-78, 2016 May 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-27105525
10.
Identification of lineariifolianoid A as a novel dual NFAT1 and MDM2 inhibitor for human cancer therapy.
J Biomed Res
; 30(4): 322-33, 2016 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-27533941
11.
Inhibiting NFAT1 for breast cancer therapy: New insights into the mechanism of action of MDM2 inhibitor JapA.
Oncotarget
; 6(32): 33106-19, 2015 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26461225
12.
Identification of a new class of natural product MDM2 inhibitor: In vitro and in vivo anti-breast cancer activities and target validation.
Oncotarget
; 6(5): 2623-40, 2015 Feb 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-25739118
13.
RYBP predicts survival of patients with non-small cell lung cancer and regulates tumor cell growth and the response to chemotherapy.
Cancer Lett
; 369(2): 386-95, 2015 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26404750
14.
Development and validation of an HPLC-MS/MS analytical method for quantitative analysis of TCBA-TPQ, a novel anticancer makaluvamine analog, and application in a pharmacokinetic study in rats.
Chin J Nat Med
; 13(7): 554-60, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26233847
15.
Oral nano-delivery of anticancer ginsenoside 25-OCH3-PPD, a natural inhibitor of the MDM2 oncogene: Nanoparticle preparation, characterization, in vitro and in vivo anti-prostate cancer activity, and mechanisms of action.
Oncotarget
; 6(25): 21379-94, 2015 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26041888
16.
RYBP expression is associated with better survival of patients with hepatocellular carcinoma (HCC) and responsiveness to chemotherapy of HCC cells in vitro and in vivo.
Oncotarget
; 5(22): 11604-19, 2014 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-25344099
17.
The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models.
Nat Commun
; 5: 5086, 2014 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25271708
18.
miRNAs in cancer prevention and treatment and as molecular targets for natural product anticancer agents.
Curr Cancer Drug Targets
; 13(5): 519-41, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23597193
19.
Selective cytotoxicity, inhibition of cell cycle progression, and induction of apoptosis in human breast cancer cells by sesquiterpenoids from Inula lineariifolia Turcz.
Eur J Med Chem
; 68: 473-481, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24044895
20.
Natural product ginsenoside 25-OCH3-PPD inhibits breast cancer growth and metastasis through down-regulating MDM2.
PLoS One
; 7(7): e41586, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22911819
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