Manipulation of electronic transport in the Bi(111) surface state.

We demonstrate the controlled manipulation of the 2D-electronic transport in the surface state of Bi(111) through the deposition of small amounts of Bi to generate adatoms and 2D islands as additional scatterers. The corresponding increase in resistance is recorded in situ and in real time. Model calculations based on mean-field nucleation theory reveal a constant scattering efficiency of adatoms and of small 2D Bi islands, independent of their size. This finding is supported by a detailed scanning tunneling microscopy and spectroscopy study at 5 K which shows a highly anisotropic scattering pattern surrounding each surface protrusion.

Magnetic proximity effect in YBa2Cu3O7/La(2/3)Ca(1/3)MnO3 and YBa2Cu3O7/LaMnO(3+δ) superlattices.

Using neutron reflectometry and resonant x-ray techniques we studied the magnetic proximity effect (MPE) in superlattices composed of superconducting YBa2Cu3O7 and ferromagnetic-metallic La0.67Ca0.33MnO3 or ferromagnetic-insulating LaMnO(3+δ). We find that the MPE strongly depends on the electronic state of the manganite layers, being pronounced for the ferromagnetic-metallic La0.67Ca0.33MnO3 and almost absent for ferromagnetic-insulating LaMnO(3+δ). We also detail the change of the magnetic depth profile due to the MPE and provide evidence for its intrinsic nature.

PTCDA on Cu(111) partially covered with NaCl.

The organic molecule 3,4,9,10-perylene-tetracarboxylic dianhydride (PTCDA) was studied by means of scanning tunneling microscopy (STM) on thin insulating NaCl films grown on a Cu(111) single crystal. The deposition of approximately two monolayers (ML) of sodium chloride onto a Cu(111) substrate at a sample temperature of about 350 K causes a rather rough growth of (100)-oriented NaCl islands up to a local height of 4 ML. For submonolayer coverages (0.1 and 0.4 ML) of PTCDA on a Cu(111) surface partly covered with NaCl, two different rod structures of PTCDA were found on the copper surface, which are in contrast to previously published data for PTCDA on Cu(111) showing a herringbone-like arrangement. These findings can be explained by the formation of a Na(x)-PTCDA complex. On NaCl covered areas, single PTCDA molecules adsorb at vacancies of [010] and [001] oriented steps of the NaCl(100) islands. In this case, the electrostatic forces between the polar step edges and the PTCDA molecules are dominant. The terraces of the alkali halide surface are free of PTCDA molecules.

Three-year follow-up of a patient with early-onset Alzheimer's disease with presenilin-2 N141I mutation - case report and review of the literature.

Autosomal dominant early-onset Alzheimer disease (EOAD) is a heterogeneous condition that has been associated with mutations in 3 different genes: the amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2) genes. Most cases are due to mutations in the PSEN1 gene, whereas mutations in the APP and PSEN2 genes are rare. Mutation analysis of the APP, PSEN1 and PSEN2 genes was performed. We herein report the case of a German EOAD patient with a family history of dementia and a missense mutation at codon 141 (N141I) of the PSEN2 gene. To our knowledge, this is the first German EOAD patient without a Volga-German ancestry and a positive family history for dementia carries the mutation PSEN-2 N141I. The patient came to our clinic for the first time when she was 47 years old. During the following 3 years, her Mini-Mental State Examination (MMSE) score dropped from 28 to 0. Mild cognitive impairment (MCI) was an early symptom that was already present during the first consultation. The concentration in cerebrospinal fluid (CSF) of tau-protein (1151 pg/ml) was increased, whereas the concentration of beta-amyloid protein (Abeta1-42) was decreased (335 pg/ml). Magnetic resonance imaging (MRI) revealed only slight changes in the early stage of the disease and positron emission tomography with (18F) fluoro-2-deoxy-D-glucose (18F-FDG PET) demonstrated glucose reduction left parietal and in the precuneus region. Follow-up MRI and 18F-FDG PET studies showed progression of atrophy of the left entorhinal cortex with relative sparing of the hippocampus and progressive hypometabolism of both temporoparietal lobes and left frontal lobe.

Polarization-dependent differential reflectance spectroscopy for real-time monitoring of organic thin film growth.

By monitoring the reflectance of a sample surface during deposition of a thin organic film, one can obtain information with submonolayer resolution in real-time. A special kind of optical spectroscopy is Differential Reflectance Spectroscopy (DRS), which compares the reflectance before and during deposition of a thin film or any other change of the surface optical properties. In this work, we present an extended DRS setup that allows monitoring simultaneously both linear polarization states (s and p) of the reflected light. We implement polarization-dependent DRS to monitor the growth of perflouropentacene thin films on a Ag(110) single crystal. The setup allows us to deduce the optical anisotropy of the sample and, in particular, the preferred orientation of the molecules on the surface.

Four-qubit device with mixed couplings.

We present the first experimental results on a device with more than two superconducting qubits. The circuit consists of four three-junction flux qubits, with simultaneous ferro- and antiferromagnetic coupling implemented using shared Josephson junctions. Its response, which is dominated by the ground state, is characterized using low-frequency impedance measurement with a superconducting tank circuit coupled to the qubits. The results are found to be in excellent agreement with the quantum-mechanical predictions.

Continuous monitoring of Rabi oscillations in a Josephson flux qubit.

Under resonant irradiation, a quantum system can undergo coherent (Rabi) oscillations in time. We report evidence for such oscillations in a continuously observed three-Josephson-junction flux qubit, coupled to a high-quality tank circuit tuned to the Rabi frequency. In addition to simplicity, this method of Rabi spectroscopy enabled a long coherence time of about 2.5 micros, corresponding to an effective qubit quality factor approximately 7000.

Evidence for entangled states of two coupled flux qubits.

We have studied the low-frequency magnetic susceptibility of two inductively coupled flux qubits using the impedance measurement technique (IMT), through their influence on the resonant properties of a weakly coupled high-quality tank circuit. In a single qubit, an IMT dip in the tank's current-voltage phase angle at the level anticrossing yields the amplitude of coherent flux tunneling. For two qubits, the difference (IMT deficit) between the sum of single-qubit dips and the dip amplitude when both qubits are at degeneracy shows that the system is in a mixture of entangled states (a necessary condition for entanglement). The dependence on temperature and relative bias between the qubits allows one to determine all the parameters of the effective Hamiltonian and equilibrium density matrix, and confirms the formation of entangled eigenstates.