Detalles de la búsqueda
1.
In Vivo Immune-Modulatory Activity of Lefamulin in an Influenza Virus A (H1N1) Infection Model in Mice.
Int J Mol Sci
; 25(10)2024 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38791439
2.
Tissue Distribution of [14C]-Lefamulin into the Urogenital Tract in Rats.
Antimicrob Agents Chemother
; 66(8): e0035522, 2022 08 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-35862748
3.
Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin Evaluation Against Pneumonia (LEAP 1) Trial.
Clin Infect Dis
; 69(11): 1856-1867, 2019 11 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30722059
4.
In vivo pharmacodynamics of lefamulin, the first systemic pleuromutilin for human use, in a neutropenic murine thigh infection model.
J Antimicrob Chemother
; 74(Suppl 3): iii5-iii10, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30949706
5.
Prediction of lefamulin epithelial lining fluid penetration after intravenous and oral administration using Phase 1 data and population pharmacokinetics methods.
J Antimicrob Chemother
; 74(Suppl 3): iii27-iii34, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30949708
6.
Pharmacokinetics/pharmacodynamics of lefamulin in a neutropenic murine pneumonia model with Staphylococcus aureus and Streptococcus pneumoniae.
J Antimicrob Chemother
; 74(Suppl 3): iii11-iii18, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30949707
7.
Pharmacokinetics and tolerability of lefamulin following intravenous and oral dosing.
J Antimicrob Chemother
; 74(Suppl 3): iii19-iii26, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30949704
8.
Pharmacokinetic/pharmacodynamic target attainment analyses to support intravenous and oral lefamulin dose selection for the treatment of patients with community-acquired bacterial pneumonia.
J Antimicrob Chemother
; 74(Suppl 3): iii35-iii41, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30949705
9.
Oral Lefamulin vs Moxifloxacin for Early Clinical Response Among Adults With Community-Acquired Bacterial Pneumonia: The LEAP 2 Randomized Clinical Trial.
JAMA
; 322(17): 1661-1671, 2019 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31560372
10.
Erratum to: Efficacy and Safety of Intravenous-to-oral Lefamulin, a Pleuromutilin Antibiotic, for the Treatment of Community-acquired Bacterial Pneumonia: The Phase III Lefamulin Evaluation Against Pneumonia (LEAP 1) Trial.
Clin Infect Dis
; 70(11): 2459, 2020 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31626688
11.
Safety and Pharmacokinetics Following Oral or Intravenous Lefamulin in Adults With Cystic Fibrosis.
Clin Ther
; 46(2): 96-103, 2024 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38195348
12.
Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections.
Front Pharmacol
; 13: 1035841, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36452226
13.
Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model.
PLoS One
; 16(9): e0237659, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34587166
14.
Pharmacokinetics and safety of lefamulin after single intravenous dose administration in subjects with impaired renal function and those requiring hemodialysis.
Pharmacotherapy
; 41(5): 451-456, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33797776
15.
Pharmacokinetics and safety of lefamulin after single intravenous dose administration in subjects with impaired-hepatic function.
Pharmacotherapy
; 41(5): 457-462, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33811377
Resultados
1 -
15
de 15
1
Próxima >
>>