[Assessment of psychological status and quality of life in patients with functional constipation].

OBJECTIVE: To investigate the states of psychological condition and the quality of life in patients with functional constipation (FC) by comparing with those of healthy controls. METHODS: Symptom Checklist-90 (SCL-90) and Patient Assessment Constipation-Quality of Life (PAC-QOL) were tested by self-report questionnaire in sixty patients with FC and thirty healthy controls with corresponding age and gender. RESULTS: (1) There was no difference in age, body mass index and sex ratio between the FC patients and healthy controls, but the scores of stool form and frequency of defecation were significantly different between the two groups. (2) The following items of SCL-90 i. e. total scores, total symptomatic index, the number of positive items and positive symptom distress level were obviously higher in the FC patients than in controls (P <0.05). The scores of the nine factors of SCL-90 except terror were also higher in the FC patients than in controls. (3) The average total score and scores of four sections (physical discomfort, psychological discomfort, anxiety, satisfaction) of PAC-QOL in FC patients were higher than those in basal level. (4) The average score of PAC-QOL was significantly correlated with the scores of SCL-90, especially in anxiety and depression. (5) The severity of symptoms in the FC patients was significantly correlated with the average score of PAC-QOL and the total score of SCL-90. CONCLUSIONS: FC patients have obviously psychological abnormality, which affects the quality of life significantly. The scores of quality of life is a better parameter to reflect the healthy status of the FC patients than the laboratory tests and the clinical symptoms.

[Features of obturator nerve by high-resolution CT at the same slice with multiplanar planar reconstruction techniques and clinic value thereof].

OBJECTIVE: To explore the features of obturator nerve (ON) by high-resolution CT (HRCT) at the same slice with multiplanar planar reconstruction techniques and clinic value thereof. METHODS: The normal lumbar vertebral bodies of 60 healthy adults and the abnormal lumbar vertebral bodies of 31 patients with ON disorders were scanned with 16-slice spiral CT, multiplanar reconstruction was conducted in the Workstation ADW4. 1, with UNIX system and DICOM form. The images at the same slice were studied. RESULTS: The shapes, thickness, direction, length, adjourning relationship, and tension could be shown at the same slice of oblique and coronal section or oblique and sagittal plane with rotation in external sides on the way from the starting point of dural sac to foramen obturatum in pelvis, meanwhile the manifestations of abnormal ON also could be shown. CONCLUSION: The anatomical features and abnormal manifestation of ON at the same slice with 16-slice spiral CT using the multiplanar reconstruction techniques can be fully shown from the starting point of dural sac to the foramen obturatum in pelvis. This technique is very important in diagnosis and treatment of diseases of obturator nerve.

[A study on HLA-DQB1 allele associated with genetic susceptibility to duodenal ulcer in Guangdong Hans].

OBJECTIVE: To study the genetic susceptibility of HLA-DQB1 alleles to duodenal ulcer in Chinese Hans from Guangdong area around. METHODS: Hundred and five patients with duodenal ulcer and hundred and five healthy controls were examined for HLA-DQB1 genotypes. HLA-DQB1 allele typing was carried out by polymerase chain reaction with sequence specific primers (PCR-SSP). RESULTS: The allele frequency of HLA-DQB1*0602 in patients with duodenal ulcer (64.8%) was significantly higher than that in healthy controls (14.3%). CONCLUSION: These findings suggest that HLA-DQB1*0602 is a susceptible gene to duodenal ulcer in Guangdong Hans of China. And at HLA-DQB1 site, there are immunogenetic differences between duodenal ulcer patients and healthy controls.

Radiology on Board the PLA(N) Peace Ark Hospital Ship During a Humanitarian Medical Relief Mission to the Philippines.

OBJECTIVE: From November 24 to December 10, 2013, the Chinese People's Liberation Army Navy [PLA(N)] hospital ship Peace Ark was deployed to the Leyte Gulf in the Philippines to provide humanitarian medical relief in Tacloban after Typhoon Haiyan. The purpose of this study was to assess the radiological services aboard the ship to provide guidance for future missions. METHODS: A retrospective review was performed on a cohort of 109 patients who underwent digital radiography (DR) and 59 patients who underwent computed tomography (CT) scans during a 16-day period during a humanitarian medical relief mission to the Philippines. Patient demographics, DR findings, and CT findings were analyzed. RESULTS: The mean age of the 109 DR patients was 39.7 years for the 64 males and 43.7 years for the 45 females. A total of 148 DR examinations were performed of the chest (n=109), extremities (n=35), and spine (n=4). The mean age of the 59 CT patients was 43.8 years for the 32 males and 49.1 years for the 27 females. A total of 72 CT scans were performed of the head and neck (n=36), thorax (n=24), abdomen (n=5), spine (n=4), and extremities (n=3). The imaging findings mainly included disaster-related and non-disaster-related fractures, pulmonary tuberculosis, pulmonary infection, acute brain infarction, intracranial hematoma, and occupying lesions. CONCLUSION: Analysis of radiological services during a humanitarian medical relief mission to the Philippines provided meaningful information for future humanitarian medical relief missions.

[Clinical, enteroscopic, and pathological characteristics of 796 cases of colorectal polyps].

OBJECTIVE: To study the age, clinical, enteroscopic and pathological characteristics of colorectal polyps and factors affected polyp-carcinoma. METHODS: We analyzed the clinical, enteroscopic and pathological characteristics of 7276 cases of colorectal polyps. RESULTS: The incidence of colorectal polyps was 10.94%, including 521 men and 275 women. The rate of colorectal polyp was 82.29% in 30-69 year olds. The adenomatous, inflammatory, hyperplastic and juvenile polyps were 43.84%, 42.09%, 11.06% and 1.51%, respectively. Polypoid lesions were located at cecum 3.29%, ascending 11.88%, transverse 4.89%, descending 11.58%, sigmoid 26.05%, and rectum 42.32%. Thirty-five cases (4.4%) were found to have polpous canceration. The canceration rates in villous, mixed and tubular adenomas were 29.73%, 11.11%, and 4.86%. The rate of canceration seemed to depend on its dimensions, being 1.3%, 7.4%, and 25.6% for the 0.6 - 1.0 cm, 1.1 - 1.9 cm, and > or = 2.0 cm in size, respectively. Conclusion The ages between 30-69 tend to suffer from colorectal polyps. The incidence in the male is higher than that in the female. Colorectal polyps are more likely to locate in left colon. The common pathological types were adenomatous and inflammatory polyps. There is a high canceration of polyps in the left colon, villous adenomas and > or = 2.0 cm polyps. The broader the pedicles and the larger the diameters of polyps are, the higher the canceration rate. All of the colon polyps should be excised and undergo the pathological examination. Enteroscopic polypectomy helps prevent colorectal polpous canceration.