Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 187
Filtrar
Más filtros

País/Región como asunto
Tipo del documento
Intervalo de año de publicación
1.
J Cutan Pathol ; 51(3): 251-257, 2024 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-38084825

RESUMEN

BACKGROUND: Apocrine cystadenoma is a rare, benign adenomatous cystic neoplasm, the pathogenesis of which is not fully understood. We sought to characterize the clinical, dermatoscopic, and histopathologic features of apocrine cystadenoma and its relationship to hidrocystoma. METHODS: We retrospectively analyzed cases of apocrine cystadenoma and hidrocystoma retrieved from the dermatopathology laboratory information system. RESULTS: Of the 350 cases apocrine cystic lesions, 13 cases of apocrine cystadenomas met the inclusion criteria. The age ranged from 20 to 84 years with an average of 64 years. They were long-standing (duration 3-15 years), slow-growing, large tumors usually found on the scalp. Dermatoscopy accentuated translucent light to dark blue color and prominent vessels that were present more at the periphery. All lesions were multilocular with columnar to cuboidal lining and decapitation secretion. A large portion of the lesion consisted of a simple nonproliferative epithelial lining, identical to that observed in apocrine hidrocystomas, while the proliferative adenomatous component made up a smaller portion with two patterns: (1) tubular proliferation, which either protruded into the cystic cavity or expanded outward peripherally, or (2) papillary projections, which were multiple layers thick with fibrovascular core, sometimes accompanied by tubular proliferation. Immunohistochemical stains showed strong staining for p40 and a sparse number of cells stained for Ki-67 and p53. CONCLUSIONS: The long duration of the lesion and the large areas of simple apocrine epithelial lining suggest that apocrine cystadenomas arise from long-standing apocrine hidrocystomas. However, the retrospective nature of the study from a single institution is a limitation.


Asunto(s)
Cistoadenoma , Hidrocistoma , Neoplasias de las Glándulas Sudoríparas , Humanos , Adulto Joven , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Hidrocistoma/patología , Estudios Retrospectivos , Neoplasias de las Glándulas Sudoríparas/patología , Glándulas Apocrinas/patología , Cistoadenoma/química , Cistoadenoma/patología , Proliferación Celular
2.
Am J Dermatopathol ; 46(7): 433-435, 2024 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-38648032

RESUMEN

ABSTRACT: Apocrine hidrocystomas are benign, cystic neoplastic lesions resulting from the apocrine secretory component of the sweat gland. They most commonly occur on the head and neck, with predilection to the periorbital area. Less frequent sites include the axilla, nipple, external auditory canal, foreskin, conjunctiva, lower lip, and fingers, among others. The authors report a unique case of a nail bed hidrocystoma in a 55-year-old woman, a site not previously described.


Asunto(s)
Hidrocistoma , Neoplasias de las Glándulas Sudoríparas , Humanos , Hidrocistoma/patología , Hidrocistoma/cirugía , Persona de Mediana Edad , Femenino , Neoplasias de las Glándulas Sudoríparas/patología , Neoplasias de las Glándulas Sudoríparas/cirugía , Enfermedades de la Uña/patología , Glándulas Apocrinas/patología , Inmunohistoquímica
3.
Am J Dermatopathol ; 45(5): 330-332, 2023 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-36939135

RESUMEN

ABSTRACT: Mucinous metaplasia (goblet cell type) is exceptionally rare in the skin. This is the second case of apocrine papillary hidrocystoma with mucinous metaplasia (goblet cell type) and a review of the literature exploring the significance and frequency of mucinous metaplasia with goblet cells in nongenital skin. The patient is an elderly man who presented with a blue-pigmented nodule on the scalp that was clinically suggestive of an atypical nevus. Histologically, the lesion was composed of a simple cyst of cuboidal cells with decapitation secretion and mucinous metaplasia with goblet cells. Papillary formation was identified in the cysts. Most cases of cutaneous mucinous metaplasia have been reported on genital skin, usually after chronic inflammation of the area. This type of mucinous metaplasia is categorized as benign mucinous metaplasia of the genitalia (BMM) and is believed to be unrelated to apocrine glands owing to the different histologic features and absence of apocrine differentiation by immunohistochemistry. Mucinous metaplasia (goblet cell type) has been previously reported in benign adnexal tumors (eccrine acrospiroma/hidroadenoma, mixed tumor, and syringocystadenoma papilliferum) and in malignant tumors (apocrine hidradenocarcinoma and squamous cell carcinoma). To date, mucinous metaplasia has not been identified in the histologically normal apocrine glands.


Asunto(s)
Acrospiroma , Adenoma de las Glándulas Sudoríparas , Hidrocistoma , Neoplasias Cutáneas , Neoplasias de las Glándulas Sudoríparas , Masculino , Humanos , Anciano , Hidrocistoma/patología , Células Caliciformes/metabolismo , Células Caliciformes/patología , Neoplasias de las Glándulas Sudoríparas/patología , Adenoma de las Glándulas Sudoríparas/patología , Neoplasias Cutáneas/patología , Acrospiroma/patología , Metaplasia/patología , Glándulas Apocrinas/patología
4.
Ophthalmic Plast Reconstr Surg ; 39(3): e96-e97, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-36806128

RESUMEN

A small ruptured cyst was excised from the left inner canthus of a 68-year-old woman. Histopathology displayed a cyst lined by a double layer of cuboidal epithelium and filled with amorphous material. The lining cells were strongly positive for cytokeratins 5/6 and 14, with weak reactivity with cytokeratin 7. These findings were identical to those in a single previous report of an eccrine cyst of the eyelid, making this the second example of a bona fide eccrine hidrocystoma of the eyelid.


Asunto(s)
Quistes , Hidrocistoma , Neoplasias de las Glándulas Sudoríparas , Femenino , Humanos , Anciano , Hidrocistoma/diagnóstico , Hidrocistoma/patología , Neoplasias de las Glándulas Sudoríparas/diagnóstico , Neoplasias de las Glándulas Sudoríparas/patología , Quistes/diagnóstico , Párpados/patología
5.
Ophthalmic Plast Reconstr Surg ; 39(5): e142-e145, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37010052

RESUMEN

An 83-year-old woman experienced the slow enlargement of a right lower eyelid mass. Histopathologic examination of the excised tissue showed a mucin-filled cystic tumor emanating from an apocrine bilayer that displayed bleb-like apocrine decapitation secretion. The outer flattened myoepithelial layer of the bilayer reacted with immunohistochemical stains for smooth muscle actin and calponin. In foci, the tumor exhibited a cribriform architecture with small pockets of mucin. Tumor cells were reactive for cytokeratin 7, Gross Cystic Disease Fluid Protein 15 (BRST-2), estrogen and progesterone receptors, androgen receptors, mammaglobin, epithelial membrane antigen, and GATA3. Ki67 showed a very low proliferation fraction. The lesion exemplifies the fourth instance of an eyelid apocrine cystadenoma in the literature.


Asunto(s)
Cistoadenoma , Hidrocistoma , Neoplasias de las Glándulas Sudoríparas , Femenino , Humanos , Anciano de 80 o más Años , Biomarcadores de Tumor , Neoplasias de las Glándulas Sudoríparas/diagnóstico , Neoplasias de las Glándulas Sudoríparas/patología , Hidrocistoma/patología , Párpados/patología , Cistoadenoma/patología , Mucinas , Glándulas Apocrinas/patología
6.
Am J Dermatopathol ; 44(8): e88-e93, 2022 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-35642954

RESUMEN

ABSTRACT: Moll gland is a modified tubular-shaped apocrine sweat gland, which is located on the margin of the eyelid. Moll glands are also known as ciliary glands. The function of these glands was not well known for a long time. However, based on the different studies, it was proved that Moll glands are active from birth and have local immunologic function producing immunoglobulin A. We present a case of Moll adenocarcinoma, a type of apocrine carcinoma, arising from the right upper eyelid of a 57-year-old man. Although Moll gland cysts are frequently seen, this type of adnexal malignancy is extremely uncommon. These tumors can have variable presentation and behavior from less invasive forms to highly malignant metastatic recurrent lesions.


Asunto(s)
Adenocarcinoma , Neoplasias de los Párpados , Hidrocistoma , Neoplasias Cutáneas , Neoplasias de las Glándulas Sudoríparas , Adenocarcinoma/patología , Adenocarcinoma/cirugía , Glándulas Apocrinas/patología , Neoplasias de los Párpados/patología , Neoplasias de los Párpados/cirugía , Párpados , Hidrocistoma/patología , Hidrocistoma/cirugía , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Cutáneas/patología , Neoplasias Cutáneas/cirugía , Neoplasias de las Glándulas Sudoríparas/patología , Neoplasias de las Glándulas Sudoríparas/cirugía
7.
Ophthalmic Plast Reconstr Surg ; 38(4): e112-e113, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-35797674

RESUMEN

Apocrine hidrocystomas are benign cystic tumors derived from apocrine sweat glands; they are most commonly located in the skin of the head and neck regions. Ophthalmic occurrences typically appear at the lash line and canthi of the eyelid, although rare instances have been described in the conjunctiva, caruncle, and orbit. The authors illustrate an exceptional instance of a mobile episcleral cyst in a 12-year-old girl that developed about 2 years following strabismus surgery. The cyst was located anterior to the insertion of the left medial rectus and was excised in response to the patient's complaints of irritation. Histopathology of the excised specimen displayed an empty cyst lined by a double layer of cuboidal epithelium with the inner layer exhibiting apical decapitation secretion. Confirmatory immunohistochemistry demonstrated reactivity of both layers with CK7 and the outer myoepithelial layer with D2-40. Postoperative and traumatic cysts formed after interruption of the bulbar conjunctiva are usually conjunctival cysts lined by stratified squamous nonkeratinizing epithelium.


Asunto(s)
Quistes , Hidrocistoma , Estrabismo , Neoplasias de las Glándulas Sudoríparas , Glándulas Apocrinas/patología , Niño , Quistes/diagnóstico , Quistes/etiología , Quistes/patología , Femenino , Hidrocistoma/diagnóstico , Hidrocistoma/patología , Humanos , Estrabismo/patología , Neoplasias de las Glándulas Sudoríparas/diagnóstico , Neoplasias de las Glándulas Sudoríparas/patología , Neoplasias de las Glándulas Sudoríparas/cirugía
8.
Medicina (Kaunas) ; 58(7)2022 Jun 22.
Artículo en Inglés | MEDLINE | ID: mdl-35888558

RESUMEN

Apocrine hidrocystomas are benign cystic tumors resulting from apocrine sweat glands' proliferation. They typically present as solitary, slow-growing nodules at the head and neck, especially in the periorbital cutaneous region. We present a case of periorbital apocrine hidrocystoma in a 22-year-old woman that was treated as chalazion previously. Besides the hallmark histopathological findings of apocrine hidrocystoma, IgG4 plasma cell infiltration of the cystic wall was also found. The ratio of IgG4-to-IgG-positive plasma cells was high, whereas serum IgG4 was within the standard limit. This is, to date, the only probable IgG4-related ophthalmic disease associated with apocrine hidrocystoma.


Asunto(s)
Chalazión , Hidrocistoma , Neoplasias de las Glándulas Sudoríparas , Adulto , Chalazión/diagnóstico , Femenino , Hidrocistoma/diagnóstico , Hidrocistoma/patología , Humanos , Inmunoglobulina G , Inflamación , Células Plasmáticas/patología , Neoplasias de las Glándulas Sudoríparas/diagnóstico , Neoplasias de las Glándulas Sudoríparas/patología , Adulto Joven
9.
Dermatol Online J ; 27(12)2021 Dec 15.
Artículo en Inglés | MEDLINE | ID: mdl-35499435

RESUMEN

Apocrine hidrocystoma (AH) is a benign cystic proliferation of apocrine sweat glands that classically presents as a slow-growing nodule on the face, especially in the periorbital region. Histopathological evaluation is required to definitively diagnose an apocrine hidrocystoma. Previous studies have described apocrine hidrocystomas in unusual locations. However, the authors have identified only two reported cases of apocrine hidrocystoma in the postauricular region. We present a third case of a postauricular hidrocystoma in a 26-year-old woman, as well as a brief review of the dermoscopic findings of apocrine hidrocystomas in the existing literature.


Asunto(s)
Hidrocistoma , Neoplasias de las Glándulas Sudoríparas , Adulto , Glándulas Apocrinas/patología , Dermoscopía , Femenino , Cabeza , Hidrocistoma/diagnóstico , Hidrocistoma/patología , Humanos , Neoplasias de las Glándulas Sudoríparas/diagnóstico por imagen , Neoplasias de las Glándulas Sudoríparas/patología
10.
Dermatol Online J ; 27(1)2021 01 15.
Artículo en Inglés | MEDLINE | ID: mdl-33560798

RESUMEN

Apocrine hidrocystoma is a benign, cystic proliferation of the apocrine sweat gland that may present commonly on sun-exposed areas of the head and neck. However, given its location and features, apocrine hidrocystomas may often be confused with malignant tumors such as basal cell carcinomas or primary cutaneous mucinous carcinomas. Herein, we present an unusual case of an apocrine hidrocystoma presenting in the postauricular region and highlight the importance of histopathological examination of cystic tumors on the periauricular area.


Asunto(s)
Neoplasias de Cabeza y Cuello/patología , Hidrocistoma/patología , Neoplasias de las Glándulas Sudoríparas/patología , Adenocarcinoma Mucinoso/diagnóstico , Carcinoma Basocelular/diagnóstico , Diagnóstico Diferencial , Quiste Epidérmico/diagnóstico , Femenino , Neoplasias de Cabeza y Cuello/terapia , Hidrocistoma/terapia , Humanos , Persona de Mediana Edad , Neoplasias Cutáneas/diagnóstico , Neoplasias de las Glándulas Sudoríparas/terapia
11.
Dermatol Online J ; 26(8)2020 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-32941723

RESUMEN

Hidrocystomas are benign cysts of sweat duct epithelium that can present as single or multiple lesions, with or without pigmentation. The size is typically 1-3mm in diameter. Although hidrocystomas commonly occur in most parts of the head and neck region, occurrence on the scalp is rare. Herein, we present a 29-year-old woman with a giant pigmented apocrine hidrocystoma of the scalp, which, to our knowledge, represents the largest of its kind reported to date.


Asunto(s)
Glándulas Apocrinas/patología , Neoplasias de Cabeza y Cuello/patología , Hidrocistoma/patología , Neoplasias de las Glándulas Sudoríparas/patología , Adulto , Femenino , Humanos , Pigmentación , Cuero Cabelludo/patología
12.
Ann Dermatol Venereol ; 147(5): 361-365, 2020 May.
Artículo en Francés | MEDLINE | ID: mdl-32164923

RESUMEN

BACKGROUND: Apocrine hidrocystomas are benign cystic tumors that develop from apocrine gland proliferation. In most cases, they are translucent solitary lesions of the face, generally found in the periorbital region, on the scalp or on the neck. More rarely, apocrine hidrocystomas may be multiple and appear on the ears, trunk, shoulders and genital area. They generally appear in adulthood, with only a few pediatric cases being reported, of which three in the genital area, with a solitary case of multiple hidrocystomas of the scrotum, although no cases of spontaneous involution of hidrocystomas have previously been reported. PATIENTS AND METHODS: Two boys aged 4 and 6 months were seen in consultation for small sub-millimeter size, subcutaneous, black lesions on the scrotum that appeared in the weeks following birth. Histological examination of these lesions resulted in a diagnosis of apocrine hidrocystoma. The children were seen again a few weeks later and the skin lesions had totally disappeared. We report two cases of multiple apocrine hidrocystomas on the scrotum with spontaneous involution diagnosed in a 4- and a 6-month-old boy. DISCUSSION: Apocrine hidrocystomas are rare benign adnexal tumors that develop from apocrine sweat glands. They are considered as cystic proliferations of the apocrine glands rather than simple retention cysts. The main differential diagnosis of the rare cases of multiple apocrine hidrocystomas are eccrine hidrocystomas. The treatment of such lesions is based on surgical excision if they are isolated, daily application of topical atropine 1%, or CO2 laser for multiple apocrine hidrocystomas.


Asunto(s)
Glándulas Apocrinas , Neoplasias de los Genitales Masculinos/patología , Hidrocistoma/patología , Escroto , Neoplasias de las Glándulas Sudoríparas/patología , Humanos , Lactante , Masculino
13.
Dermatol Online J ; 25(2)2019 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-30865415

RESUMEN

Eccrine hidrocystoma is a benign cystic tumor. Such benign cystic lesions may be a cosmetic concern, or when large, can cause eyelid malpositions. We report a patient with a peri-punctal hidrocystoma of the eyelid.


Asunto(s)
Neoplasias de los Párpados/cirugía , Hidrocistoma/cirugía , Neoplasias de las Glándulas Sudoríparas/cirugía , Adulto , Glándulas Ecrinas , Neoplasias de los Párpados/patología , Hidrocistoma/patología , Humanos , Aparato Lagrimal , Masculino , Neoplasias de las Glándulas Sudoríparas/patología
14.
Dermatol Online J ; 25(6)2019 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-31329389

RESUMEN

Apocrine hidrocystoma is a benign, cystic lesion often presenting in the periorbital region. Apocrine adenocarcinoma is the rare, malignant counterpart occurring mainly in the axilla and anogenital region. There is a paucity of literature on both entities and co-occurrence has been reported in only 5 cases. We present the case of a 48-year-old man with a history of total body irradiation for chronic myelocytic leukemia, diabetes mellitus, and obesity who presented with a calf mass of two years' duration. Epidermal inclusion cyst was presumed and excisional biopsy was carried out. Pathologic analysis revealed apocrine adenocarcinoma in the setting of a precursor apocrine hidrocystoma. Our patient's unique altered immunity and the direct effects of irradiation on the local microenvironment may have resulted in his rare presentation of co-occurrence of apocrine adenocarcinoma within an existing apocrine hidrocystoma. To our knowledge, our patient is the first reported patient with this presentation in the lower extremity.


Asunto(s)
Adenocarcinoma/patología , Hidrocistoma/patología , Pierna , Neoplasias de las Glándulas Sudoríparas/patología , Adenocarcinoma/complicaciones , Hidrocistoma/complicaciones , Humanos , Leucemia Mielógena Crónica BCR-ABL Positiva/radioterapia , Masculino , Persona de Mediana Edad , Neoplasias de las Glándulas Sudoríparas/complicaciones , Irradiación Corporal Total
15.
Pediatr Dermatol ; 35(4): e231-e232, 2018 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-29633329

RESUMEN

Apocrine hidrocystomas are mostly found on the cheeks and eyelids but also on the scalp and neck. The age distribution is from 30 to 70 years old. We report a case of an apocrine hidrocystoma on the genitalia of a 9-year-old girl.


Asunto(s)
Genitales/patología , Hidrocistoma/patología , Neoplasias de las Glándulas Sudoríparas/patología , Niño , Diagnóstico Diferencial , Femenino , Humanos
16.
Ophthalmic Plast Reconstr Surg ; 34(3): e83-e85, 2018.
Artículo en Inglés | MEDLINE | ID: mdl-29351118

RESUMEN

A 53-year-old man presented with smooth-domed, variegated cysts (polycystic disease) of all 4 eyelids, worse on the left side. Some of the cysts were clear, while others were creamy-white colored. In addition, multiple, very fine vesicopapules were noted along the eyelid margins. Histopathologic examination revealed a trichilemmal cyst, several pure apocrine hidrocystomas displaying multiple chambers, a hybrid cyst, and many small eccrine cysts of the deep dermis. The apocrine lesions, including the small ones at the eyelid margins, predominated. Smooth muscle actin sometimes positively stained outer myoepithelial cells in some of the apocrine cysts, which helped to distinguish them from eccrine cysts. Most noteworthy was the fact that the patient had been diagnosed with a prolactinoma 20 years earlier. There is only 1 previous report of multiple apocrine cysts and an antecedent prolactinoma in the dermatologic literature. This syndrome should be separated from that of Schöpf-Schulz-Passarge, which manifests multiple small eyelid apocrine cysts and other ectodermal dysplasias without any association with neoplasia, and from that of focal dermal hypoplasia (Goltz-Gorlin) syndrome with apocrine cysts but again without neoplasia.


Asunto(s)
Quiste Epidérmico/patología , Neoplasias de los Párpados/patología , Hidrocistoma/patología , Neoplasias Hipofisarias/complicaciones , Prolactinoma/complicaciones , Neoplasias de las Glándulas Sudoríparas/patología , Glándulas Apocrinas/patología , Glándulas Ecrinas/patología , Humanos , Masculino , Persona de Mediana Edad
17.
J Cutan Pathol ; 44(8): 698-702, 2017 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-28497640

RESUMEN

Polarizable calcium oxalate (CaOx) crystals have been well documented in breast biopsies, generally associated with benign apocrine metaplasia. In contrast, polarizable crystals are only rarely reported in skin adnexal neoplasms. We report 3 different cases of sweat gland tumors with polarizable crystals morphologically suggestive of CaOx: 1 apocrine hidrocystoma and 2 tubular apocrine adenomas. The histologic features were examined in 3 cases. Clinical presentation summary included 2 males and 1 female, ages 53 to 74 years, with lesions located on the left cheek, inferior vertex scalp and the left eyebrow. All 3 cases showed polarizable, geometric, plate-like and fractured, colorless crystals within the lumens of the neoplasm. Of note, these crystals were seen only on the toluidine blue-stained section of Case #1, but were not present on the corresponding permanent section. We hypothesize that polarizable crystals may be present in sweat gland neoplasms more often than previously documented, but that they may often dissolve with routine processing, accounting for their rare visibility. We highlight this rare finding, and suggest that it may be underreported. We only noted this finding in benign apocrine tumors; further investigation would be necessary to determine whether these crystals are also seen in other cutaneous adnexal neoplasms.


Asunto(s)
Adenoma , Glándulas Apocrinas , Oxalato de Calcio/metabolismo , Hidrocistoma , Neoplasias de las Glándulas Sudoríparas , Adenoma/metabolismo , Adenoma/patología , Anciano , Glándulas Apocrinas/metabolismo , Glándulas Apocrinas/patología , Femenino , Hidrocistoma/metabolismo , Hidrocistoma/patología , Humanos , Masculino , Persona de Mediana Edad , Neoplasias de las Glándulas Sudoríparas/metabolismo , Neoplasias de las Glándulas Sudoríparas/patología
18.
Hautarzt ; 68(5): 393-395, 2017 May.
Artículo en Alemán | MEDLINE | ID: mdl-27872944

RESUMEN

Multiple eccrine hidrocystomas are benign cystic skin lesions which originate from the sweat gland ducts and typically affect women's midfacial area. Sweating may lead to an increase in size of the translucent papules. In some cases hidrocystomas are associated with other diseases such as Parkinson's disease. Treatment options include laser, topical and systemic anticholinergic drugs (glycopyrrolate, clonidine, atropine, and oxybutynin), whereby therapeutic success is limited in most cases.


Asunto(s)
Hidrocistoma/patología , Hidrocistoma/terapia , Neoplasias Primarias Múltiples/patología , Neoplasias Primarias Múltiples/terapia , Neoplasias de las Glándulas Sudoríparas/patología , Neoplasias de las Glándulas Sudoríparas/terapia , Diagnóstico Diferencial , Humanos , Masculino , Persona de Mediana Edad
19.
Dermatol Online J ; 23(9)2017 Sep 15.
Artículo en Inglés | MEDLINE | ID: mdl-29469730

RESUMEN

Hidrocystomas are benign cysts that typically present as translucent, bluish dermal nodules on the face and are rarely > 1 cm in size. They are classically categorized as eccrine or apocrine based on histologic features. We present a rare case of a giant apocrine hidrocystoma of the trunk, demonstrating that, although a rare variant, apocrine hidrocystomas can present both off the head and neck, and can be significantly larger in size than previously reported.


Asunto(s)
Hidrocistoma/diagnóstico , Hidrocistoma/patología , Neoplasias de las Glándulas Sudoríparas/diagnóstico , Neoplasias de las Glándulas Sudoríparas/patología , Anciano , Glándulas Apocrinas , Humanos , Masculino
20.
Am J Dermatopathol ; 38(7): 549-52, 2016 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-26981739

RESUMEN

Adenomyoepithelioma (AME) is a biphasic neoplasm of epithelial and myoepithelial cells. It is most commonly found in the breast, although rare cases have been reported from the lung, salivary glands, and skin. There are 5 well-documented cases of cutaneous AME in the literature. We report a new case of cutaneous AME. Our case was commingled with apocrine hidrocystoma. This is the first report of cutaneous AME in a male patient and the first to describe SOX10 immunostaining in cutaneous AME. We review the literature on cutaneous AME and note the greater than chance colocalization with other adnexal tumors. We speculate that AME may represent localized overgrowth of myoepithelial cells within a pre-existent sweat gland tumor. Histopathologists should be aware of the potential of SOX10-positive myoepithelial neoplasms to mimic nodular melanocytic proliferations.


Asunto(s)
Adenomioepitelioma/patología , Glándulas Apocrinas/patología , Hidrocistoma/patología , Neoplasias Complejas y Mixtas/patología , Neoplasias Cutáneas/patología , Neoplasias de las Glándulas Sudoríparas/patología , Adenomioepitelioma/química , Adenomioepitelioma/cirugía , Adulto , Anciano de 80 o más Años , Glándulas Apocrinas/química , Glándulas Apocrinas/cirugía , Biomarcadores de Tumor/análisis , Biopsia , Femenino , Hidrocistoma/química , Hidrocistoma/cirugía , Humanos , Inmunohistoquímica , Masculino , Persona de Mediana Edad , Neoplasias Complejas y Mixtas/química , Neoplasias Complejas y Mixtas/cirugía , Factores de Transcripción SOXE/análisis , Neoplasias Cutáneas/química , Neoplasias Cutáneas/cirugía , Neoplasias de las Glándulas Sudoríparas/química , Neoplasias de las Glándulas Sudoríparas/cirugía , Resultado del Tratamiento
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA