Diagnostic accuracy of lugol chromoendoscopy in the oesophagus in patients with head and neck cancer
Rev. esp. enferm. dig
; 105(2): 79-83, feb. 2013. tab, ilus
Article
in En
| IBECS
| ID: ibc-154272
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Background and aim: patients with head and neck squamous cell malignancies have a higher risk of oesophageal squamous cell carcinomas. Lugol chromoendoscopy in oesophagus is a simple technique with a high diagnostic yield in premalignant lesions. The objective was to analyze its diagnostic accuracy in dysplasia and carcinoma of the oesophagus in high-risk patients. Methods: prospective study from April/2008 to January/2012 using lugol chromoendoscopy with biopsies of suspicious lugol voiding areas ≥ 5 mm. Patients with head and neck malignancies were included, except the ones with iodine allergy, oesophageal varices and contra-indications to standard endoscopy. The reference method was histopathology. Results: 89 patients were enrolled (mean age 62.8 ± 13.3 years, 87 % men). Primary tumour was located in oropharynx in 37 (41.6 %), in oral cavity in 29 (32.6 %) and in the larynx in 23 (25.8 %) cases. 40.4 % patients had previous treatments and 87 % reported alcohol or tobacco addition. All exams performed without anaesthesia or complications. Nine suspicious lugol voiding areas were observed and biopsied. Histopathological analysis revealed high-grade dysplasia in 2 (2.2 %) and inflammation or normal findings in the others. The sensitivity and specificity for detecting high-grade dysplasia were 100 % and 92 % (95 % CI: 87-97), respectively. Diagnostic accuracy of the test was 92 % (95 % CI: 86-98). Conclusion: lugol staining of the oesophagus during endoscopy seems to be a feasible, safe and justified procedure in high-risk population as it enhances the detection of premalignant lesions (AU)
RESUMEN
No disponible
Full text:
1
Collection:
06-national
/
ES
Database:
IBECS
Main subject:
Esophageal Neoplasms
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Carcinoma, Squamous Cell
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Esophagoscopy
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Coloring Agents
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Head and Neck Neoplasms
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Iodides
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Neoplasms, Multiple Primary
Type of study:
Diagnostic_studies
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Evaluation_studies
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Observational_studies
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Risk_factors_studies
Limits:
Adult
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Female
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Humans
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Male
Language:
En
Journal:
Rev. esp. enferm. dig
Year:
2013
Type:
Article