Adaptor Proteins, Signal Transducing; Endothelium, Vascular/metabolism; Fibroblast Growth Factor 2/metabolism; Genes, ras; src Homology Domains; Animals; Becaplermin; Calcium-Calmodulin-Dependent Protein Kinases/drug effects; Calcium-Calmodulin-Dependent Protein Kinases/metabolism; Cell Adhesion Molecules/drug effects; Cell Adhesion Molecules/metabolism; Cell Differentiation/drug effects; Cell Differentiation/physiology; Cell Division/physiology; Cell Line; Endothelium, Vascular/cytology; Endothelium, Vascular/drug effects; Enzyme Inhibitors/pharmacology; Fibroblast Growth Factor 2/pharmacology; Flavonoids/pharmacology; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GRB2 Adaptor Protein; Indoles/pharmacology; Isoenzymes/drug effects; Isoenzymes/metabolism; Maleimides/pharmacology; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mice; Mice, Transgenic; Phospholipase C gamma; Phosphoproteins/genetics; Phosphoproteins/metabolism; Platelet-Derived Growth Factor/metabolism; Platelet-Derived Growth Factor/pharmacology; Protein Kinase C/antagonists & inhibitors; Protein Kinase C/drug effects; Protein Kinase C/metabolism; Protein-Tyrosine Kinases/drug effects; Protein-Tyrosine Kinases/metabolism; Proteins/genetics; Proteins/metabolism; Proto-Oncogene Proteins c-sis; Receptor Protein-Tyrosine Kinases/genetics; Receptor Protein-Tyrosine Kinases/metabolism; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor/genetics; Receptors, Fibroblast Growth Factor/metabolism; Recombinant Proteins/genetics; Recombinant Proteins/metabolism; Signal Transduction; Type C Phospholipases/drug effects; Type C Phospholipases/metabolism; ras Proteins/genetics