Overexpression of insulin-like growth factor II (IGFII) in ZR-75-1 human breast cancer cells: higher threshold levels of receptor (IGFIR) are required for a proliferative response than for effects on specific gene expression.

Abdul-Wahab, K; Corcoran, D; Perachiotti, A; Darbre, P D

Abdul-Wahab, K; Corcoran, D; Perachiotti, A; Darbre, P D.

Affiliation

Abdul-Wahab K; Division of Cell and Molecular Biology, School of Animal and Microbial Sciences, The University of Reading, UK.

Cell Prolif ; 32(5): 271-87, 1999 Oct.

Article in En | MEDLINE | ID: mdl-10619489

Subject(s)

Breast Neoplasms/genetics; Breast Neoplasms/metabolism; Insulin-Like Growth Factor II/genetics; Receptor, IGF Type 1/metabolism; Breast Neoplasms/pathology; Cell Division/drug effects; Estradiol/pharmacology; Female; Gene Expression; Humans; Insulin-Like Growth Factor II/metabolism; Insulin-Like Growth Factor II/pharmacology; Neoplasms, Hormone-Dependent/genetics; Neoplasms, Hormone-Dependent/metabolism; Neoplasms, Hormone-Dependent/pathology; Proprotein Convertase 2; RNA, Messenger/genetics; RNA, Messenger/metabolism; RNA, Neoplasm/genetics; RNA, Neoplasm/metabolism; Receptor, IGF Type 1/genetics; Subtilisins/genetics; Transfection; Tumor Cells, Cultured; Zinc/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Insulin-Like Growth Factor II / Receptor, IGF Type 1 Limits: Female / Humans Language: En Journal: Cell Prolif Year: 1999 Type: Article Affiliation country: United kingdom

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