Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation.

Touil, N; Elhajouji, A; Thierens, H; Kirsch-Volders, M

Touil, N; Elhajouji, A; Thierens, H; Kirsch-Volders, M.

Affiliation

Touil N; Free University of Brussels, Laboratory for Cell Genetics, Pleinlaan 2, B-1050 Brussels, Belgium. ntouil@pop.vub.ac.be

Mutagenesis ; 15(1): 1-7, 2000 Jan.

Article in En | MEDLINE | ID: mdl-10640524

Subject(s)

Aneuploidy; Chromosome Segregation/radiation effects; Gamma Rays; Lymphocytes/radiation effects; Adult; Cell Division/physiology; Chromosomes, Human, Pair 1/radiation effects; Chromosomes, Human, Pair 17/radiation effects; Cytochalasin B/pharmacology; Female; Humans; In Situ Hybridization, Fluorescence; In Vitro Techniques; Lymphocytes/cytology; Lymphocytes/ultrastructure; Male; Micronuclei, Chromosome-Defective/radiation effects; Middle Aged; Nondisjunction, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Lymphocytes / Chromosome Segregation / Gamma Rays / Aneuploidy Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Mutagenesis Journal subject: GENETICA MEDICA / SAUDE AMBIENTAL Year: 2000 Type: Article Affiliation country: Belgium

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