Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells.

Jiang, B H; Zheng, J Z; Aoki, M; Vogt, P K

Jiang, B H; Zheng, J Z; Aoki, M; Vogt, P K.

Affiliation

Jiang BH; The Scripps Research Institute, Department of Molecular Medicine, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Proc Natl Acad Sci U S A ; 97(4): 1749-53, 2000 Feb 15.

Article in En | MEDLINE | ID: mdl-10677529

Subject(s)

Endothelial Growth Factors/genetics; Endothelium, Vascular/embryology; Lymphokines/genetics; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases/genetics; Protein Serine-Threonine Kinases; Signal Transduction; Animals; Chick Embryo; Chorion/metabolism; Endothelial Growth Factors/metabolism; Fibroblasts; Gene Expression Regulation, Developmental; Genes, Tumor Suppressor; Immunohistochemistry; Lymphokines/metabolism; Oncogenes/genetics; Phosphatidylinositol 3-Kinases/metabolism; Plasmids; Proto-Oncogene Proteins/genetics; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-akt; RNA, Messenger/metabolism; Retroviridae/genetics; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endothelium, Vascular / Signal Transduction / Endothelial Growth Factors / Lymphokines / Protein Serine-Threonine Kinases / Neovascularization, Physiologic / Phosphatidylinositol 3-Kinases Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2000 Type: Article Affiliation country: United States

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