Regional oral absorption, hepatic first-pass effect, and non-linear disposition of salmon calcitonin in beagle dogs.

Hee Lee, Y; Leesman, G D; Makhey, V; Yu, H; Hu, P; Perry, B; Sutyak, J P; Wagner, E J; Falzone, L M; Stern, W; Sinko, P J

Hee Lee, Y; Leesman, G D; Makhey, V; Yu, H; Hu, P; Perry, B; Sutyak, J P; Wagner, E J; Falzone, L M; Stern, W; Sinko, P J.

Affiliation

Hee Lee Y; Department of Pharmaceutics, Rutgers University, College of Pharmacy, Piscataway, NJ 08854, USA.

Eur J Pharm Biopharm ; 50(2): 205-11, 2000 Sep.

Article in En | MEDLINE | ID: mdl-10962228

Subject(s)

Calcitonin/pharmacokinetics; Intestinal Absorption; Liver/metabolism; Administration, Oral; Animals; Dogs; Dose-Response Relationship, Drug; Male; Skin Absorption

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Collection: 01-internacional Database: MEDLINE Main subject: Calcitonin / Intestinal Absorption / Liver Type of study: Prognostic_studies Limits: Animals Language: En Journal: Eur J Pharm Biopharm Journal subject: FARMACIA / FARMACOLOGIA Year: 2000 Type: Article Affiliation country: United States

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