Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice.

Dufresne, S D; Bjørbaek, C; El-Haschimi, K; Zhao, Y; Aschenbach, W G; Moller, D E; Goodyear, L J

Dufresne, S D; Bjørbaek, C; El-Haschimi, K; Zhao, Y; Aschenbach, W G; Moller, D E; Goodyear, L J.

Affiliation

Dufresne SD; Research Division, Joslin Diabetes Center, Boston, Massachusetts 02215, USA.

Mol Cell Biol ; 21(1): 81-7, 2001 Jan.

Article in En | MEDLINE | ID: mdl-11113183

Subject(s)

Gene Deletion; Glycogen/metabolism; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases/metabolism; Muscle, Skeletal/metabolism; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases/metabolism; Animals; Body Weight/genetics; Cognition/physiology; Disease Models, Animal; Enzyme Activation/drug effects; Feedback; Gene Expression Regulation, Enzymologic; Gene Targeting; Glycogen Synthase/metabolism; Insulin/pharmacology; MAP Kinase Signaling System/drug effects; Mice; Mice, Knockout; Muscle, Skeletal/drug effects; Muscle, Skeletal/enzymology; Phosphorylation/drug effects; Physical Conditioning, Animal/physiology; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases/deficiency; Ribosomal Protein S6 Kinases/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Serine-Threonine Kinases / Gene Deletion / Muscle, Skeletal / Ribosomal Protein S6 Kinases / Mitogen-Activated Protein Kinases / MAP Kinase Signaling System / Glycogen Limits: Animals Language: En Journal: Mol Cell Biol Year: 2001 Type: Article Affiliation country: United States

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