A comparative study of cellular and molecular pharmacology of doxorubicin and MEN 10755, a disaccharide analogue.

Bigioni, M; Salvatore, C; Bullo, A; Bellarosa, D; Iafrate, E; Animati, F; Capranico, G; Goso, C; Maggi, C A; Pratesi, G; Zunino, F; Manzini, S

Bigioni, M; Salvatore, C; Bullo, A; Bellarosa, D; Iafrate, E; Animati, F; Capranico, G; Goso, C; Maggi, C A; Pratesi, G; Zunino, F; Manzini, S.

Affiliation

Bigioni M; Department of Pharmacology, Menarini Ricerche S.p.A., Pomezia, Rome, Italy.

Biochem Pharmacol ; 62(1): 63-70, 2001 Jul 01.

Article in En | MEDLINE | ID: mdl-11377397

Subject(s)

Antineoplastic Agents/pharmacology; Disaccharides/pharmacology; Doxorubicin/pharmacology; Apoptosis; Cell Cycle/drug effects; DNA Adducts/metabolism; DNA Damage/drug effects; DNA Topoisomerases, Type I/metabolism; DNA Topoisomerases, Type II/metabolism; Disaccharides/chemistry; Doxorubicin/analogs & derivatives; Humans; Subcellular Fractions; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Doxorubicin / Disaccharides / Antineoplastic Agents Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2001 Type: Article Affiliation country: Italy

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