Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener, M S; Münchenhagen, P M; Berger, I; Morgan, N V; Roigas, J; Schwiertz, A; Jürgensen, J S; Gruber, G; Maxwell, P H; Löning, S A; Frei, U; Maher, E R; Gröne, H J; Eckardt, K U

Wiesener, M S; Münchenhagen, P M; Berger, I; Morgan, N V; Roigas, J; Schwiertz, A; Jürgensen, J S; Gruber, G; Maxwell, P H; Löning, S A; Frei, U; Maher, E R; Gröne, H J; Eckardt, K U.

Affiliation

Wiesener MS; Department of Nephrology and Medical Intensive Care, Charité, Humboldt University, 13353 Berlin, Germany.

Cancer Res ; 61(13): 5215-22, 2001 Jul 01.

Article in En | MEDLINE | ID: mdl-11431362

Subject(s)

Carcinoma, Renal Cell/genetics; DNA-Binding Proteins/genetics; Endothelial Growth Factors/genetics; Gene Expression Regulation, Neoplastic; Kidney Neoplasms/genetics; Ligases; Lymphokines/genetics; Monosaccharide Transport Proteins/genetics; Nuclear Proteins/genetics; Transcription Factors; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Adenocarcinoma, Clear Cell/genetics; Adenocarcinoma, Clear Cell/metabolism; Carcinoma, Renal Cell/metabolism; Cell Hypoxia/genetics; DNA Mutational Analysis; DNA-Binding Proteins/biosynthesis; Endothelial Growth Factors/biosynthesis; Glucose Transporter Type 1; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kidney Neoplasms/metabolism; Lymphokines/biosynthesis; Monosaccharide Transport Proteins/biosynthesis; Nuclear Proteins/biosynthesis; Proteins/genetics; RNA, Messenger/biosynthesis; RNA, Messenger/genetics; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Von Hippel-Lindau Tumor Suppressor Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Monosaccharide Transport Proteins / Nuclear Proteins / Carcinoma, Renal Cell / Gene Expression Regulation, Neoplastic / Endothelial Growth Factors / Lymphokines / Tumor Suppressor Proteins / Ubiquitin-Protein Ligases / DNA-Binding Proteins Limits: Humans Language: En Journal: Cancer Res Year: 2001 Type: Article Affiliation country: Germany

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