Detection of APC mutations in fecal DNA from patients with colorectal tumors.

Traverso, Giovanni; Shuber, Anthony; Levin, Bernard; Johnson, Constance; Olsson, Louise; Schoetz, David J; Hamilton, Stanley R; Boynton, Kevin; Kinzler, Kenneth W; Vogelstein, Bert

Traverso, Giovanni; Shuber, Anthony; Levin, Bernard; Johnson, Constance; Olsson, Louise; Schoetz, David J; Hamilton, Stanley R; Boynton, Kevin; Kinzler, Kenneth W; Vogelstein, Bert.

Affiliation

Traverso G; Graduate Program in Human Genetics, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Johns Hopkins School of Medicine, Baltimore, USA.

N Engl J Med ; 346(5): 311-20, 2002 Jan 31.

Article in En | MEDLINE | ID: mdl-11821507

Subject(s)

Colorectal Neoplasms/diagnosis; Feces; Genes, APC; Mutation; Adenoma/diagnosis; Adenoma/genetics; Adenomatous Polyposis Coli Protein/analysis; Adult; Aged; Biomarkers, Tumor/analysis; Biomarkers, Tumor/genetics; Case-Control Studies; Colorectal Neoplasms/genetics; DNA Mutational Analysis/methods; Feasibility Studies; Female; Humans; Male; Middle Aged; Polymerase Chain Reaction/methods; Sensitivity and Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Genes, APC / Feces / Mutation Type of study: Diagnostic_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Screening_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: N Engl J Med Year: 2002 Type: Article Affiliation country: United States

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