Retroviral transduction of splice variant Brca1-Delta11 or mutant Brca1-W1777Stop causes mouse epithelial mammary atypical duct hyperplasia.

Bachelier, Richard; Vincent, Anne; Mathevet, Patrice; Magdinier, Frédérique; Lenoir, Gilbert M; Frappart, Lucien

Bachelier, Richard; Vincent, Anne; Mathevet, Patrice; Magdinier, Frédérique; Lenoir, Gilbert M; Frappart, Lucien.

Affiliation

Bachelier R; Laboratoire de génétique, UMR 5641 CNRS, Université Claude Bernard Lyon I, Faculté de Médecine, 8 avenue Rockefeller, 69373 Lyon cedex 08, France.

Virchows Arch ; 440(3): 261-6, 2002 Mar.

Article in En | MEDLINE | ID: mdl-11889595

Subject(s)

Alternative Splicing/genetics; BRCA1 Protein/genetics; Mammary Glands, Animal/pathology; Mammary Neoplasms, Experimental/genetics; Precancerous Conditions/genetics; Protein Isoforms/genetics; Transduction, Genetic; Animals; BRCA1 Protein/metabolism; DNA, Neoplasm/analysis; Epithelial Cells/pathology; Female; Hyperplasia; Mammary Glands, Animal/metabolism; Mammary Neoplasms, Experimental/metabolism; Mammary Neoplasms, Experimental/pathology; Mice; Mice, Inbred BALB C; Mutation; Polymerase Chain Reaction; Precancerous Conditions/metabolism; Precancerous Conditions/pathology; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Precancerous Conditions / Transduction, Genetic / Alternative Splicing / BRCA1 Protein / Protein Isoforms / Mammary Glands, Animal / Mammary Neoplasms, Experimental Type of study: Etiology_studies Limits: Animals Language: En Journal: Virchows Arch Journal subject: BIOLOGIA MOLECULAR / PATOLOGIA Year: 2002 Type: Article Affiliation country: France

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