Epigenetic inactivation of 14-3-3 sigma in oral carcinoma: association with p16(INK4a) silencing and human papillomavirus negativity.

Gasco, Milena; Bell, Alexandra K; Heath, Victoria; Sullivan, Alex; Smith, Paul; Hiller, Louise; Yulug, Isik; Numico, Gianmauro; Merlano, Marco; Farrell, Paul J; Tavassoli, Mahvash; Gusterson, Barry; Crook, Tim

Gasco, Milena; Bell, Alexandra K; Heath, Victoria; Sullivan, Alex; Smith, Paul; Hiller, Louise; Yulug, Isik; Numico, Gianmauro; Merlano, Marco; Farrell, Paul J; Tavassoli, Mahvash; Gusterson, Barry; Crook, Tim.

Affiliation

Gasco M; UO Oncologia Medica, Azienda Ospedaliera S Croce e Carle, 12100 Cuneo, Italy.

Cancer Res ; 62(7): 2072-6, 2002 Apr 01.

Article in En | MEDLINE | ID: mdl-11929827

Subject(s)

Biomarkers, Tumor; Carcinoma, Squamous Cell/genetics; Cyclin-Dependent Kinase Inhibitor p16/genetics; Exonucleases; Mouth Neoplasms/genetics; Neoplasm Proteins; Papillomaviridae/genetics; Precancerous Conditions/genetics; Proteins/genetics; 14-3-3 Proteins; Carcinoma, Squamous Cell/metabolism; Carcinoma, Squamous Cell/virology; Cyclin-Dependent Kinase Inhibitor p16/biosynthesis; DNA Methylation; DNA, Viral/analysis; Exoribonucleases; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Loss of Heterozygosity; Mouth Neoplasms/metabolism; Mouth Neoplasms/virology; Mutation; Papillomavirus Infections/complications; Papillomavirus Infections/virology; Precancerous Conditions/metabolism; Precancerous Conditions/virology; Protein Biosynthesis; Tumor Suppressor Protein p53/genetics; Tumor Virus Infections/complications; Tumor Virus Infections/virology

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Collection: 01-internacional Database: MEDLINE Main subject: Papillomaviridae / Precancerous Conditions / Mouth Neoplasms / Carcinoma, Squamous Cell / Proteins / Biomarkers, Tumor / Cyclin-Dependent Kinase Inhibitor p16 / Exonucleases / Neoplasm Proteins Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Cancer Res Year: 2002 Type: Article Affiliation country: Italy

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