Antibacterial activities and characterization of novel inhibitors of LpxC.

Clements, John M; Coignard, Fanny; Johnson, Ian; Chandler, Stephen; Palan, Shilpa; Waller, Andrew; Wijkmans, Jac; Hunter, Michael G

Clements, John M; Coignard, Fanny; Johnson, Ian; Chandler, Stephen; Palan, Shilpa; Waller, Andrew; Wijkmans, Jac; Hunter, Michael G.

Affiliation

Clements JM; British Biotech Pharmaceuticals Ltd., Oxford OX4 6LY, United Kingdom. clements@britbio.co.uk

Antimicrob Agents Chemother ; 46(6): 1793-9, 2002 Jun.

Article in En | MEDLINE | ID: mdl-12019092

Subject(s)

Amidohydrolases/antagonists & inhibitors; Anti-Bacterial Agents/pharmacology; Bacteria/drug effects; Enzyme Inhibitors/pharmacology; Naphthalenes/pharmacology; Sulfonamides/pharmacology; Amidohydrolases/genetics; Bacteria/enzymology; Bacteria/genetics; DNA, Recombinant/genetics; Drug Resistance, Microbial; Drug Synergism; Escherichia coli/genetics; Genotype; Hydro-Lyases/genetics; Microbial Sensitivity Tests; Mutation/genetics; Plasmids/genetics; Reverse Transcriptase Polymerase Chain Reaction; Time Factors

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sulfonamides / Bacteria / Enzyme Inhibitors / Amidohydrolases / Anti-Bacterial Agents / Naphthalenes Type of study: Prognostic_studies Language: En Journal: Antimicrob Agents Chemother Year: 2002 Type: Article Affiliation country: United kingdom

Fulltext

XML

PubMed Links

Search on Google