Changing homeodomain residues 2 and 3 of Hoxa1 alters its activity in a cell-type and enhancer dependent manner.

Remacle, Sophie; Shaw-Jackson, Chloë; Matis, Christelle; Lampe, Xavier; Picard, Jacques; Rezsöhazy, René

Remacle, Sophie; Shaw-Jackson, Chloë; Matis, Christelle; Lampe, Xavier; Picard, Jacques; Rezsöhazy, René.

Affiliation

Remacle S; Unité de Génétique du Développement, UCL 7382, Université Catholique de Louvain, B-1200 Bruxelles, Belgium.

Nucleic Acids Res ; 30(12): 2663-8, 2002 Jun 15.

Article in En | MEDLINE | ID: mdl-12060683

Subject(s)

Enhancer Elements, Genetic; Homeodomain Proteins/chemistry; Homeodomain Proteins/metabolism; Trans-Activators/chemistry; Trans-Activators/metabolism; Transcription Factors/chemistry; Transcription Factors/metabolism; Amino Acid Substitution; Animals; Cell Line; DNA-Binding Proteins/metabolism; Herpes Simplex Virus Protein Vmw65/genetics; Homeodomain Proteins/genetics; Humans; Pre-B-Cell Leukemia Transcription Factor 1; Protein Structure, Tertiary; Proto-Oncogene Proteins/metabolism; Recombinant Fusion Proteins/metabolism; Somatostatin/genetics; Structure-Activity Relationship; Trans-Activators/genetics; Transcription Factors/genetics; Transcriptional Activation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Trans-Activators / Enhancer Elements, Genetic / Homeodomain Proteins Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2002 Type: Article Affiliation country: Belgium

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