Segregation of B and T cell epitopes of Treponema pallidum repeat protein K to variable and conserved regions during experimental syphilis infection.

Morgan, Cecilia A; Molini, Barbara J; Lukehart, Sheila A; Van Voorhis, Wesley C

Morgan, Cecilia A; Molini, Barbara J; Lukehart, Sheila A; Van Voorhis, Wesley C.

Affiliation

Morgan CA; Department of Pathobiology, University of Washington, Seattle, WA 98195, USA.

J Immunol ; 169(2): 952-7, 2002 Jul 15.

Article in En | MEDLINE | ID: mdl-12097401

Subject(s)

Antigenic Variation/immunology; Bacterial Outer Membrane Proteins/immunology; Conserved Sequence/immunology; Epitopes, B-Lymphocyte/immunology; Epitopes, T-Lymphocyte/immunology; Peptide Fragments/immunology; Syphilis/immunology; Treponema pallidum/immunology; Amino Acid Sequence; Animals; Antibodies, Bacterial/biosynthesis; Bacterial Outer Membrane Proteins/metabolism; Epitopes, B-Lymphocyte/metabolism; Epitopes, T-Lymphocyte/metabolism; Lymphocyte Activation; Male; Molecular Sequence Data; Peptide Fragments/metabolism; Rabbits; Syphilis/microbiology; T-Lymphocyte Subsets/immunology; T-Lymphocyte Subsets/microbiology; Treponema pallidum/pathogenicity

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Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Bacterial Outer Membrane Proteins / Treponema pallidum / Antigenic Variation / Syphilis / Conserved Sequence / Epitopes, T-Lymphocyte / Epitopes, B-Lymphocyte Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2002 Type: Article Affiliation country: United States

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