Identification of threonine 66 as a functionally critical residue of the interleukin-1 receptor-associated kinase.

Ross, Kehinde; Yang, Lin; Dower, Steve; Volpe, Filippo; Guesdon, Francois

Ross, Kehinde; Yang, Lin; Dower, Steve; Volpe, Filippo; Guesdon, Francois.

Affiliation

Ross K; Division of Genomic Medicine, University of Sheffield, M Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom.

J Biol Chem ; 277(40): 37414-21, 2002 Oct 04.

Article in En | MEDLINE | ID: mdl-12138165

Subject(s)

Protein Kinases/chemistry; Threonine; 3T3 Cells; Amino Acid Sequence; Animals; COS Cells; Chlorocebus aethiops; Conserved Sequence; Green Fluorescent Proteins; Humans; Interleukin-1 Receptor-Associated Kinases; Luminescent Proteins/genetics; Mice; Microscopy, Confocal; Peptide Fragments/chemistry; Protein Kinases/genetics; Protein Kinases/physiology; Protein Structure, Secondary; Receptors, Interleukin-1/chemistry; Receptors, Interleukin-1/physiology; Recombinant Fusion Proteins/chemistry; Recombinant Fusion Proteins/metabolism; Sequence Homology, Amino Acid; Signal Transduction/physiology; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinases / Threonine Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2002 Type: Article Affiliation country: United kingdom

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