Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system.

Haskell, R E; Hughes, S M; Chiorini, J A; Alisky, J M; Davidson, B L

Haskell, R E; Hughes, S M; Chiorini, J A; Alisky, J M; Davidson, B L.

Affiliation

Haskell RE; Program in Gene Therapy, Department of Internal medicine, University of Iowa College of Medicine, Iowa City, IA 52252, USA.

Gene Ther ; 10(1): 34-42, 2003 Jan.

Article in En | MEDLINE | ID: mdl-12525835

Subject(s)

Central Nervous System/metabolism; Genetic Therapy/methods; Models, Animal; Neuronal Ceroid-Lipofuscinoses/therapy; Nucleotidases/genetics; Adenoviridae/genetics; Animals; Genetic Engineering; Genetic Vectors/administration & dosage; Humans; Immunohistochemistry/methods; Injections; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Transduction, Genetic/methods; Tripeptidyl-Peptidase 1

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Collection: 01-internacional Database: MEDLINE Main subject: Genetic Therapy / Central Nervous System / Models, Animal / Neuronal Ceroid-Lipofuscinoses / Nucleotidases Limits: Animals / Humans Language: En Journal: Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2003 Type: Article Affiliation country: United States

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