Peptide nucleic acid antisense prolongs skin allograft survival by means of blockade of CXCR3 expression directing T cells into graft.

Jiankuo, Ming; Xingbing, Wang; Baojun, Huang; Xiongwin, Wu; Zhuoya, Li; Ping, Xiong; Yong, Xu; Anting, Liu; Chunsong, Hu; Feili, Gong; Jinquan, Tan

Jiankuo, Ming; Xingbing, Wang; Baojun, Huang; Xiongwin, Wu; Zhuoya, Li; Ping, Xiong; Yong, Xu; Anting, Liu; Chunsong, Hu; Feili, Gong; Jinquan, Tan.

Affiliation

Jiankuo M; Department of Immunology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.

J Immunol ; 170(3): 1556-65, 2003 Feb 01.

Article in En | MEDLINE | ID: mdl-12538721

Subject(s)

Chemotaxis, Leukocyte/immunology; Graft Survival/immunology; Oligonucleotides, Antisense/pharmacology; Peptide Nucleic Acids/pharmacology; Receptors, Chemokine/antagonists & inhibitors; Receptors, Chemokine/physiology; Skin Transplantation/immunology; T-Lymphocytes/immunology; Acute Disease; Animals; Chemotaxis, Leukocyte/genetics; Disease Progression; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligonucleotides, Antisense/therapeutic use; Peptide Nucleic Acids/therapeutic use; Receptors, CXCR3; Receptors, Chemokine/biosynthesis; Receptors, Chemokine/genetics; Skin Transplantation/pathology; T-Lymphocytes/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Chemotaxis, Leukocyte / Oligonucleotides, Antisense / Skin Transplantation / Receptors, Chemokine / Peptide Nucleic Acids / Graft Survival Limits: Animals Language: En Journal: J Immunol Year: 2003 Type: Article

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