Kinases as therapeutic targets for heart failure.

Vlahos, Chris J; McDowell, Susan A; Clerk, Angela

Vlahos, Chris J; McDowell, Susan A; Clerk, Angela.

Affiliation

Vlahos CJ; Cardiovascular Research, Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA. Vlahos_Chris_J@Lilly.Com

Nat Rev Drug Discov ; 2(2): 99-113, 2003 Feb.

Article in En | MEDLINE | ID: mdl-12563301

Subject(s)

Enzyme Inhibitors/therapeutic use; Heart Failure/drug therapy; Phosphotransferases/antagonists & inhibitors; Phosphotransferases/physiology; Animals; Heart Failure/prevention & control; Humans; Isoenzymes/antagonists & inhibitors; Isoenzymes/metabolism; Mitogen-Activated Protein Kinases/antagonists & inhibitors; Mitogen-Activated Protein Kinases/metabolism; Myocardium/enzymology; Phosphatidylinositol 3-Kinases/metabolism; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C/antagonists & inhibitors; Protein Kinase C/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Phosphotransferases / Enzyme Inhibitors / Heart Failure Limits: Animals / Humans Language: En Journal: Nat Rev Drug Discov Journal subject: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2003 Type: Article Affiliation country: United States

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