Investigation of the lectin-like binding domains in pertussis toxin using synthetic peptide sequences. Identification of a sialic acid binding site in the S2 subunit of the toxin.

Heerze, L D; Chong, P C; Armstrong, G D

Heerze, L D; Chong, P C; Armstrong, G D.

Affiliation

Heerze LD; Department of Medical Microbiology and Infectious Disease, University of Alberta, Edmonton, Canada.

J Biol Chem ; 267(36): 25810-5, 1992 Dec 25.

Article in En | MEDLINE | ID: mdl-1281475

Subject(s)

Lectins/metabolism; Peptide Fragments/metabolism; Peptides/metabolism; Pertussis Toxin; Sialic Acids/metabolism; Virulence Factors, Bordetella/metabolism; Amino Acid Sequence; Binding Sites; Binding, Competitive; Enzyme-Linked Immunosorbent Assay; Kinetics; Macromolecular Substances; Molecular Sequence Data; N-Acetylneuraminic Acid; Peptide Fragments/chemical synthesis; Peptides/chemical synthesis; Virulence Factors, Bordetella/chemistry; alpha-Fetoproteins/metabolism

Search on Google

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Peptides / Sialic Acids / Virulence Factors, Bordetella / Pertussis Toxin / Lectins Type of study: Diagnostic_studies / Prognostic_studies Language: En Journal: J Biol Chem Year: 1992 Type: Article Affiliation country: Canada

Search on Google

XML

PubMed Links