Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1.

Bivona, Trever G; Pérez De Castro, Ignacio; Ahearn, Ian M; Grana, Theresa M; Chiu, Vi K; Lockyer, Peter J; Cullen, Peter J; Pellicer, Angel; Cox, Adrienne D; Philips, Mark R

Bivona, Trever G; Pérez De Castro, Ignacio; Ahearn, Ian M; Grana, Theresa M; Chiu, Vi K; Lockyer, Peter J; Cullen, Peter J; Pellicer, Angel; Cox, Adrienne D; Philips, Mark R.

Affiliation

Bivona TG; Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, New York 10016, USA.

Nature ; 424(6949): 694-8, 2003 Aug 07.

Article in En | MEDLINE | ID: mdl-12845332

Subject(s)

DNA-Binding Proteins/metabolism; Golgi Apparatus/metabolism; Guanine Nucleotide Exchange Factors; Type C Phospholipases/metabolism; ras Proteins/metabolism; Animals; COS Cells; Calcium/metabolism; Cell Differentiation; Cell Membrane/metabolism; Enzyme Activation; Fibroblasts; Humans; Intracellular Membranes/metabolism; Jurkat Cells; PC12 Cells; Phospholipase C gamma; Protein Transport; Proto-Oncogene Proteins pp60(c-src)/metabolism; Rats; Signal Transduction; ras GTPase-Activating Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Type C Phospholipases / Ras Proteins / Guanine Nucleotide Exchange Factors / DNA-Binding Proteins / Golgi Apparatus Limits: Animals / Humans Language: En Journal: Nature Year: 2003 Type: Article Affiliation country: United States

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