Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase.

Winzell, Maria Sörhede; Svensson, Håkan; Enerbäck, Sven; Ravnskjaer, Kim; Mandrup, Susanne; Esser, Victoria; Arner, Peter; Alves-Guerra, Marie-Clotilde; Miroux, Bruno; Sundler, Frank; Ahrén, Bo; Holm, Cecilia

Winzell, Maria Sörhede; Svensson, Håkan; Enerbäck, Sven; Ravnskjaer, Kim; Mandrup, Susanne; Esser, Victoria; Arner, Peter; Alves-Guerra, Marie-Clotilde; Miroux, Bruno; Sundler, Frank; Ahrén, Bo; Holm, Cecilia.

Affiliation

Winzell MS; Department of Cell and Molecular Biology, Lund University, Lund, Sweden. maria.sorhede_winzell@medkem.lu.se

Diabetes ; 52(8): 2057-65, 2003 Aug.

Article in En | MEDLINE | ID: mdl-12882923

Subject(s)

Islets of Langerhans/enzymology; Membrane Transport Proteins; Mitochondrial Proteins; Sterol Esterase/genetics; Sterol Esterase/metabolism; Triglycerides/metabolism; Animals; Blood Glucose/metabolism; Body Weight; Fatty Acids/metabolism; Female; Gene Expression Regulation, Enzymologic; Glucose Transporter Type 2; Immunohistochemistry; Ion Channels; Islets of Langerhans/chemistry; Islets of Langerhans/growth & development; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Monosaccharide Transport Proteins/analysis; Oxidation-Reduction; Phenotype; Proteins/metabolism; Rats; Uncoupling Protein 2; Up-Regulation

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Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Triglycerides / Sterol Esterase / Islets of Langerhans / Mitochondrial Proteins Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Diabetes Year: 2003 Type: Article Affiliation country: Sweden

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