The wt1-heterozygous mouse; a model to study the development of glomerular sclerosis.

Menke, Aswin L; IJpenberg, Annemieke; Fleming, Stewart; Ross, Allyson; Medine, Claire N; Patek, Charles E; Spraggon, Lee; Hughes, Jeremy; Clarke, Alan R; Hastie, Nicholas D

Menke, Aswin L; IJpenberg, Annemieke; Fleming, Stewart; Ross, Allyson; Medine, Claire N; Patek, Charles E; Spraggon, Lee; Hughes, Jeremy; Clarke, Alan R; Hastie, Nicholas D.

Affiliation

Menke AL; MRC Human Genetics Unit, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, Scotland, UK.

J Pathol ; 200(5): 667-74, 2003 Aug.

Article in En | MEDLINE | ID: mdl-12898605

Subject(s)

Disease Models, Animal; Glomerulosclerosis, Focal Segmental/genetics; WT1 Proteins/genetics; Albuminuria/genetics; Animals; Creatinine/blood; Female; Glomerulosclerosis, Focal Segmental/metabolism; Glomerulosclerosis, Focal Segmental/pathology; Heterozygote; Kidney/ultrastructure; Kidney Failure, Chronic/genetics; Male; Mice; Mice, Inbred Strains; Proteinuria/genetics; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Urea/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Glomerulosclerosis, Focal Segmental / WT1 Proteins / Disease Models, Animal Limits: Animals Language: En Journal: J Pathol Year: 2003 Type: Article Affiliation country: United kingdom

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