The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor.

Wu, Jiao-Hui; Peppel, Karsten; Nelson, Christopher D; Lin, Fang-Tsyr; Kohout, Trudy A; Miller, William E; Exum, Sabrina T; Freedman, Neil J

Wu, Jiao-Hui; Peppel, Karsten; Nelson, Christopher D; Lin, Fang-Tsyr; Kohout, Trudy A; Miller, William E; Exum, Sabrina T; Freedman, Neil J.

Affiliation

Wu JH; Department of Medicine (Cardiology), Duke University Medical Center, Durham, North Carolina 27710, USA.

J Biol Chem ; 278(45): 44238-45, 2003 Nov 07.

Article in En | MEDLINE | ID: mdl-12944399

Subject(s)

Arrestins/physiology; Endocytosis; Receptors, LDL/metabolism; Animals; Arrestins/deficiency; Arrestins/genetics; CHO Cells; Cell Line; Cholesterol/blood; Cholesterol, HDL/blood; Cholesterol, LDL/blood; Cloning, Molecular; Cricetinae; Dietary Fats/administration & dosage; Embryo, Mammalian; Fibroblasts; Gene Expression; Glutathione Transferase/genetics; Humans; Immunosorbent Techniques; Kidney; Lipoproteins/blood; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis; Receptors, LDL/genetics; Recombinant Fusion Proteins; Transfection; beta-Arrestins

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, LDL / Arrestins / Endocytosis Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2003 Type: Article Affiliation country: United States

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